ID   A0A2A9F3Y5_9VIBR        Unreviewed;       477 AA.
AC   A0A2A9F3Y5;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=AGCS family alanine or glycine:cation symporter {ECO:0000313|EMBL:PFG45210.1};
GN   ORFNames=ATG66_3487 {ECO:0000313|EMBL:PFG45210.1};
OS   Vibrio sp. ES.051.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=1761909 {ECO:0000313|EMBL:PFG45210.1, ECO:0000313|Proteomes:UP000223114};
RN   [1] {ECO:0000313|EMBL:PFG45210.1, ECO:0000313|Proteomes:UP000223114}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ES.051 {ECO:0000313|EMBL:PFG45210.1,
RC   ECO:0000313|Proteomes:UP000223114};
RA   Fredrickson J.;
RT   "Microbial Interactions in Extremophilic Mat Communities.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|RuleBase:RU363064}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PFG45210.1}.
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DR   EMBL; PDJL01000006; PFG45210.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A9F3Y5; -.
DR   OrthoDB; 9806926at2; -.
DR   Proteomes; UP000223114; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF1; AMINO-ACID CARRIER PROTEIN ALST; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
DR   PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane {ECO:0000256|RuleBase:RU363064};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        12..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        137..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        173..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        206..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        233..257
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        301..320
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        348..371
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        392..413
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        419..439
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   477 AA;  51191 MW;  8EC65A5597A53991 CRC64;
     MTDLINLIND LLWGSILVYL LVGVGIYFTV RLGFIQFRHF GHMFSVLKNS RKADKAGISS
     FQALCTSLAA RVGTGNMAGV AVALTAGGPG AIFWMWLIAM LGMATSFAES TLAQLYKTKD
     DDGNYRGGPA YYMEKGLGMR WMGVLFSIFL IIAFGLVFNA VQANSIANAM SAAFGWSDFY
     VGIAVVALSS IVIFGGIKRI AKVAELIVPV MALLYLALAL FVMFSNLEKL PDVLMLIIKS
     AFGLQEAAAG GLGYAIAQAM INGVKRGLFS NEAGMGSAPN AAASATPYPP HPASQGYVQM
     LGVFMDTIVI CSSTVAIILM SGEYVGQATE VTGIELTQRA LSSQVGDWGG IFVAIAIFFF
     AFTSIIANYS YAETNLIFLE HNHKAGLSIF RVIVLGMVMF GAMASLPVVW SLADVSMGLM
     AIVNLVAIIL LSGIVIKLAK DYNRQLDEGK VPTFDANDFP ELKSQLEEGI WYSDKKD
//