ID   A0A2A9MFH5_9APIC        Unreviewed;       548 AA.
AC   A0A2A9MFH5;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Pre-mRNA-splicing factor cwc2 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BESB_048610 {ECO:0000313|EMBL:PFH36669.1};
OS   Besnoitia besnoiti.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Sarcocystidae; Besnoitia.
OX   NCBI_TaxID=94643 {ECO:0000313|EMBL:PFH36669.1, ECO:0000313|Proteomes:UP000224006};
RN   [1] {ECO:0000313|EMBL:PFH36669.1, ECO:0000313|Proteomes:UP000224006}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bb-Ger1 {ECO:0000313|EMBL:PFH36669.1,
RC   ECO:0000313|Proteomes:UP000224006};
RA   Schares G., Venepally P., Lorenzi H.A.;
RT   "Genome sequencing of Besnoitia besnoiti strain Bb-Ger1.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the RRM CWC2 family.
CC       {ECO:0000256|ARBA:ARBA00008024}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PFH36669.1}.
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DR   EMBL; NWUJ01000003; PFH36669.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2A9MFH5; -.
DR   STRING; 94643.A0A2A9MFH5; -.
DR   VEuPathDB; ToxoDB:BESB_048610; -.
DR   OrthoDB; 929875at2759; -.
DR   Proteomes; UP000224006; Chromosome iii.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.70.330; -; 1.
DR   InterPro; IPR039171; Cwc2/Slt11.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   InterPro; IPR032297; Torus.
DR   InterPro; IPR000571; Znf_CCCH.
DR   PANTHER; PTHR14089:SF2; PRE-MRNA-SPLICING FACTOR CWC2; 1.
DR   PANTHER; PTHR14089; PRE-MRNA-SPLICING FACTOR RBM22; 1.
DR   Pfam; PF16131; Torus; 1.
DR   SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR   PROSITE; PS50102; RRM; 1.
DR   PROSITE; PS50103; ZF_C3H1; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW   ProRule:PRU00723}; mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000224006};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW   ProRule:PRU00176};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00723}.
FT   DOMAIN          218..240
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50103"
FT   DOMAIN          278..360
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   ZN_FING         218..240
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT   REGION          1..67
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          363..391
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          482..504
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..37
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        363..384
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   548 AA;  60449 MW;  3FF745C6B241A423 CRC64;
     MASSTSSNPA EHMADGGNTG GGGSNSPTQT QELGCPTHRQ LSEAHDSVVR PVSNNPGEEV
     RSLRPTPSVL TSAAQGVQLD CANASLPTDV LLTENQYALY AAYYQWYYHA AQEARNSLLS
     DNMTNRTQLQ EHPPDSKRDI VKKWMKRPAR QQIDQNEASR YSHCEGGTEY NIWYGKYLTD
     RYNKPSYLDR ETAPYKCNPK RDAGYTRANT DASGEHFFCI YYAKGGCCLG KNCRFRHSVP
     TADDEGHLEW SYDIFGRERF STHKDDMDGV GSFNHDCKTL FVGGFCIDSE IPDGLKKMES
     FLLKEFSAWG DVTCIRVIPK KNIAFITYAY RVQAEFAKVA MADQNLGKQA PLLLVKWAHH
     DGNANKRRTD EEEEAKRKRQ KELTEIGPSM PSADGVHPGA FPFLPEGSAC RDAAGDAAAV
     SATLQGHYNT WQVLSADVPE KADSMSARFS QAAYLHGSFL QDWAALYDGC SEKDVDAAPR
     PLAEQMPKPN AESSGGGDPS ASPLISTDEA EEALGRMQHI LNRIDGLDAT AFEVPMHSLS
     APVYPQIS
//