ID   A0A2B4RB22_STYPI        Unreviewed;      1463 AA.
AC   A0A2B4RB22;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=NACHT, LRR and PYD domains-containing protein 3 {ECO:0000313|EMBL:PFX14009.1};
GN   Name=NLRP3 {ECO:0000313|EMBL:PFX14009.1};
GN   ORFNames=AWC38_SpisGene21872 {ECO:0000313|EMBL:PFX14009.1};
OS   Stylophora pistillata (Smooth cauliflower coral).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC   Astrocoeniina; Pocilloporidae; Stylophora.
OX   NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX14009.1, ECO:0000313|Proteomes:UP000225706};
RN   [1] {ECO:0000313|Proteomes:UP000225706}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA   Tambutte S., Allemand D., Aranda M.;
RT   "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT   digitifera provides evidence for extensive differences between species of
RT   corals.";
RL   bioRxiv 0:0-0(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PFX14009.1}.
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DR   EMBL; LSMT01000855; PFX14009.1; -; Genomic_DNA.
DR   STRING; 50429.A0A2B4RB22; -.
DR   Proteomes; UP000225706; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd03801; GT4_PimA-like; 1.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR049341; TRADD-like_N.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   Pfam; PF20706; GT4-conflict; 1.
DR   Pfam; PF13516; LRR_6; 4.
DR   Pfam; PF20694; TRADD-like_N; 1.
DR   SMART; SM00368; LRR_RI; 7.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000225706};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          731..787
FT                   /note="TRADD-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF20694"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          904..925
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          966..1046
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1463 AA;  165198 MW;  1F94AB30B3EA2F42 CRC64;
     MASSSALTAA SGEEENKEQR PTDVMFLCDE WKSSKGGIST FNREFAINLA ETTTGSMKIH
     CYVSKSDDQD REDAKQHGVN LITARSVPGS SDPFERLKFP PSELPNPQLV IGHGRKLGIP
     AYFLVKSTKC KWIQFVHVYC EDVGKYKKTT MAATDTIEEN EKKHKEEIDL CKVADAVVAV
     GSRLQQKYGR SLLNVKVEII TPGIVGKFFN ESKLAVDRSV VKNFNVFMFG RATYEDRSLK
     GYDIIAKAID SLGKNFDLTF VGSSPGEYEE VEQWFLDNSG IKRNQLTIRG YCSEQEELKM
     MFFQADLVAQ PSRTEGFGLV SLEAISAGIP VLVSGQSGIA EALQKVEGGN AVIVGSDEDA
     YEWAQRIREI SEQSVEEREA NALKLRENYG KLYSWREECE KFKGMIERVM KNMFQLNTSK
     RKLFEEEKQF EETHEAKRLL LDDREQALET SKQLMNTALD EKENELYSLH AGFEKIKALA
     ESTKKESSAV TQQNELLKSM ISTLGLDFKQ FSKSKWEQNN TSAATKPTTR HRRRKETQKA
     LKFIHGGSSG SFYGAWDYIV ANAPKELVGE FITAYKRGKY IQEVFEKAMK EHQASPEALK
     QAIATKYQNF LSRRKFNVVC KTQTSYFNAE ANYCTHFCNF LSLIINQKLN IKVDVEQLKL
     ADHDACSTAS VSAVEPAGCQ KASTTSGICR KRRFDAEKED FQSLEKKVLC LIAMNYLNTT
     PPQSRDEHNE FREYLQEMKV LISSVSMGSL LITVKCDSLE SLEELWEDYL CGLLDKMVRD
     CFVTEKILKE LNLAELKLKT TMDVEEYNAC KLYFKKDALR GTSPLTVIPT TGHGKQLKEP
     TGRIGTSLST MLPTAGHGKE LEGRLKTMKL QEEKRILSLP GPSTFDPEEE LEELCRVLQL
     GEDTSPSTVL STSGHKKGLR KTEKVRHKIV KPQGKKGMLP LHGTSTHNPE KGVEELGSLP
     SPPLSTTDLE EKLEEVCVKL KRLRMEGSLP AHQSSTSHVE VKLAELQMEL KRLRMEGTRP
     PPELFTDLLE RELEKLRVQI TRKRQKGSSP LPDCTLDEEI REILEKLQQK RIEELENTMY
     PTIISGLAKF DVSLPEELQS YSSYLLNESA KLGLRRKVSQ RPSAVQKLRE AMDKYELKTF
     LTIHIREGAW QVVLLFTDEL RSRKLPSDWC ETKWDWHEKM LISSIYSSAS GILKAWPTEC
     DPDLVTLCKA ITNRDWKVTR LFFSRCRLSN EGLKNLSTAL VQGELYSLAM YDNALQAQGL
     KHLCEALMRS DSNLISLSII RNWLGVEGIM HLCHVLTSVN CKLTSLNVCR NLFGSEGLKH
     LCDALISANC TLTSLNLRYN KLGNEGIKPL FTILTSSNCT LTSLDVSFNR LGDRVLKDLA
     KTLTNTDCTL TSLVIRSNLI GDEGIKYLCK ALTDVKCKLR SLDLQENRKV TDVGKQCLSE
     AITGTDWKVR RGLKLSRTTN SEA
//