ID A0A2B4RCF4_STYPI Unreviewed; 399 AA.
AC A0A2B4RCF4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Plasma kallikrein {ECO:0000313|EMBL:PFX14473.1};
GN Name=Klkb1 {ECO:0000313|EMBL:PFX14473.1};
GN ORFNames=AWC38_SpisGene21368 {ECO:0000313|EMBL:PFX14473.1};
OS Stylophora pistillata (Smooth cauliflower coral).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC Astrocoeniina; Pocilloporidae; Stylophora.
OX NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX14473.1, ECO:0000313|Proteomes:UP000225706};
RN [1] {ECO:0000313|Proteomes:UP000225706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA Tambutte S., Allemand D., Aranda M.;
RT "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT digitifera provides evidence for extensive differences between species of
RT corals.";
RL bioRxiv 0:0-0(2017).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01005}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFX14473.1}.
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DR EMBL; LSMT01000776; PFX14473.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2B4RCF4; -.
DR STRING; 50429.A0A2B4RCF4; -.
DR EnsemblMetazoa; XM_022951998.1; XP_022807733.1; LOC111344747.
DR OrthoDB; 2909016at2759; -.
DR Proteomes; UP000225706; Unassembled WGS sequence.
DR GO; GO:0042151; C:nematocyst; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR GO; GO:0007596; P:blood coagulation; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00190; Tryp_SPc; 1.
DR Gene3D; 1.10.10.1870; ShTK domain-like; 2.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 1.
DR InterPro; IPR012224; Pept_S1A_FX.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR003582; ShKT_dom.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR InterPro; IPR033116; TRYPSIN_SER.
DR PANTHER; PTHR24252; ACROSIN-RELATED; 1.
DR PANTHER; PTHR24252:SF7; HYALIN; 1.
DR Pfam; PF01549; ShK; 2.
DR Pfam; PF00089; Trypsin; 1.
DR PIRSF; PIRSF001143; Factor_X; 1.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00254; ShKT; 2.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS51670; SHKT; 2.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
DR PROSITE; PS00135; TRYPSIN_SER; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU01005}; Hydrolase {ECO:0000256|RuleBase:RU363034};
KW Protease {ECO:0000256|RuleBase:RU363034};
KW Reference proteome {ECO:0000313|Proteomes:UP000225706};
KW Serine protease {ECO:0000256|RuleBase:RU363034};
KW Signal {ECO:0000256|SAM:SignalP}; Toxin {ECO:0000256|ARBA:ARBA00022656}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..399
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012451121"
FT DOMAIN 49..83
FT /note="ShKT"
FT /evidence="ECO:0000259|PROSITE:PS51670"
FT DOMAIN 87..121
FT /note="ShKT"
FT /evidence="ECO:0000259|PROSITE:PS51670"
FT DOMAIN 156..392
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
FT ACT_SITE 199
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR001143-1"
FT ACT_SITE 249
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR001143-1"
FT ACT_SITE 344
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR001143-1"
FT DISULFID 49..83
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01005"
FT DISULFID 87..121
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01005"
SQ SEQUENCE 399 AA; 44362 MW; CCCA5B9C165253FA CRC64;
MLISFSSLIF LIYCAYFSQE REMSLQEGIT AGLETLSDEN NSSTKRAACE DLNSYCNIYK
PYCKHIEYVD FVKVNCKKTC DLCPKACLDR VSYCHVIKNR CTDPVIGGSV RRFCAKTCGV
CVVTPPTIPP TTIPRTEQPI DQGSVECGRK AVGSRIVGGT NARPGAWPWQ VTMDYKGHSG
PHWCGGSIVT PHYILTAAHC FGSGDDPKDY SIVAGEHDLN TVDGFEQNTT IQEIIIHPKY
NRIANHDYDV ALVKLKNPIR YNNHVRPVCL AKSDFDSGTN CYVTGWGYTS EDGSIAQILQ
QAIVPLVSRE KCQEGYNDLG YKISTRMRCA GYSEGKIDAC QGDSGGPLVC VRNDKWYLMG
VISWGQGCAR KGRYGVYADM MDLKFWVQQT INKGYQSKI
//
