ID   A0A2B4RDN7_STYPI        Unreviewed;       996 AA.
AC   A0A2B4RDN7;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase {ECO:0000313|EMBL:PFX14478.1};
GN   Name=lpxA {ECO:0000313|EMBL:PFX14478.1};
GN   ORFNames=AWC38_SpisGene21358 {ECO:0000313|EMBL:PFX14478.1};
OS   Stylophora pistillata (Smooth cauliflower coral).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC   Astrocoeniina; Pocilloporidae; Stylophora.
OX   NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX14478.1, ECO:0000313|Proteomes:UP000225706};
RN   [1] {ECO:0000313|Proteomes:UP000225706}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA   Tambutte S., Allemand D., Aranda M.;
RT   "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT   digitifera provides evidence for extensive differences between species of
RT   corals.";
RL   bioRxiv 0:0-0(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PFX14478.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LSMT01000774; PFX14478.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2B4RDN7; -.
DR   STRING; 50429.A0A2B4RDN7; -.
DR   Proteomes; UP000225706; Unassembled WGS sequence.
DR   GO; GO:0008780; F:acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009245; P:lipid A biosynthetic process; IEA:UniProtKB-KW.
DR   CDD; cd01288; FabZ; 1.
DR   CDD; cd09604; M1_APN_like; 1.
DR   Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR   Gene3D; 3.10.129.10; Hotdog Thioesterase; 1.
DR   Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR   InterPro; IPR013114; FabA_FabZ.
DR   InterPro; IPR001451; Hexapep.
DR   InterPro; IPR029069; HotDog_dom_sf.
DR   InterPro; IPR010137; Lipid_A_LpxA.
DR   InterPro; IPR014782; Peptidase_M1_dom.
DR   InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR   InterPro; IPR011004; Trimer_LpxA-like_sf.
DR   PANTHER; PTHR43480; ACYL-[ACYL-CARRIER-PROTEIN]--UDP-N-ACETYLGLUCOSAMINE O-ACYLTRANSFERASE; 1.
DR   PANTHER; PTHR43480:SF1; ACYL-[ACYL-CARRIER-PROTEIN]--UDP-N-ACETYLGLUCOSAMINE O-ACYLTRANSFERASE, MITOCHONDRIAL-RELATED; 1.
DR   Pfam; PF07977; FabA; 1.
DR   Pfam; PF00132; Hexapep; 1.
DR   Pfam; PF01433; Peptidase_M1; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
DR   SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 1.
DR   SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
PE   4: Predicted;
KW   Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW   ECO:0000313|EMBL:PFX14478.1};
KW   Lipid A biosynthesis {ECO:0000256|ARBA:ARBA00022556};
KW   Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000225706};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:PFX14478.1}.
FT   DOMAIN          626..820
FT                   /note="Peptidase M1 membrane alanine aminopeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF01433"
SQ   SEQUENCE   996 AA;  114239 MW;  6D858463C3145290 CRC64;
     MPFLEVLERA KIETQKTPLE IYKVKEVMNF TDADTGSEIT LLPAEDYQIT TMIDYDKEGH
     FPGSPVMPGV LQIEAMAQCG GILVLSTVPD PENYLTYFMK IDGVKFKQKV VPGDTLIFKA
     DLINPIRRGS VIGGIPQDLK FEGEETTVHI GNDTTIRECV TVNRATRASG KTVVGKNCTL
     MACSHVAHDC VVGDNVILVN GVLLGGHVKV DDYAIIGGHS AIHQFVHIGK YTMLMGGALV
     SKDVPPYVKG AKFPLSYMGI NSIGFFSTAQ QKTKQGHTNQ NKFKQLKDEF ATPNEFRTAS
     GAPGYAYTQQ QVDYKMDIVL DDETQKITGK EVITYHNNSK DVLEYFWIQL DQNRRSKNSK
     SDDIEVDNNM MYAGVKSFAN MITAPKGGFN ITAVKGKNDD DLDYTINRTM MRLDLPTPLK
     PGEKFVFKIH WWYYINEYLK EKSSGRSGFE HFEKDGNNLY VIAQFFPRLC VYDNVEGWQN
     MQFWGRSEFA LEFGNYTVNI TTPKDHILNA TGVLMNPEEV LTQKQFKRWQ KAKTTFKKPM
     FIVTEKEARK AEKKKAKQTK TWQFYAENVR DFGFASSRKF IWDAMAVDIN GKTVMAYSLY
     PKEGNPLWEA YSTKVVAHSL KTYSKYTFDY PYHKAISVHA RSQGMEYPQI CWNYGRPRKD
     GTYSERTKHG MIGVITHEVG HNFFPMIVNS DERQWTWMDE GLNSYMDALT QLEFNEKFGE
     KIDPRSAPKD IVPYMSGDQS QLAPIMTQGD NVYRFGPNAY TKPAAGLFLL RNTILGPKLF
     DKAFSTYAKR WMFKHPTPED FFRTMEDASG TDLDWFWRGW FYTTDVTDIG IKAVHKLYAT
     EKPSDEFVQM LRKRGFDEKR IKEILKDKRI YFTKKDRSKK QATAYKKSKM LKKYSTLGKM
     KTPAYFYELT FEKPGGLVMP IIVEFTYADG TKSRKTYPAQ IWRKNDKEVT KIFPSEKEIK
     SIAIDPDLET ADVDTSNNHW PPKKENLFDL KKRQLN
//