ID A0A2B4RE46_STYPI Unreviewed; 727 AA.
AC A0A2B4RE46;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 22-FEB-2023, entry version 15.
DE SubName: Full=SLIT-ROBO Rho GTPase-activating protein 1 {ECO:0000313|EMBL:PFX15089.1};
GN Name=SRGAP1 {ECO:0000313|EMBL:PFX15089.1};
GN ORFNames=AWC38_SpisGene20706 {ECO:0000313|EMBL:PFX15089.1};
OS Stylophora pistillata (Smooth cauliflower coral).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC Astrocoeniina; Pocilloporidae; Stylophora.
OX NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX15089.1, ECO:0000313|Proteomes:UP000225706};
RN [1] {ECO:0000313|Proteomes:UP000225706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA Tambutte S., Allemand D., Aranda M.;
RT "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT digitifera provides evidence for extensive differences between species of
RT corals.";
RL bioRxiv 0:0-0(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFX15089.1}.
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DR EMBL; LSMT01000687; PFX15089.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2B4RE46; -.
DR STRING; 50429.A0A2B4RE46; -.
DR Proteomes; UP000225706; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR14166:SF17; RHO-GAP DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR14166; SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000225706}.
FT DOMAIN 72..336
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 516..704
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 45..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 707..727
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 220..264
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 47..70
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 727 AA; 83292 MW; CA2766E835F69756 CRC64;
MEQKKILIRS ALLHAATVLT KISFVYRAKK VCLCHHHYAG NPVEGHKFPA SEEKLQERRG
EKRAGEREKS KSQVRQILIE QLKCFDNRTE GKLLFLADMQ EFFRRLSEIE MEYSRNLERL
SKMYLDKLHR HRTQRKEKGT TMDLWQQVLI ETKNKSKMHQ GLSENVSSNI VNRFMIISDD
CQRISKQCRE TATTLQEELV RSVQELSRKV HRYHAIALES KTAEQKLQKM EDSRRKNEKM
AKQVEKHQQK STECKKRCVK AKNEYVLSLE STNRFLENYY NGFLKTLVDT FDYNYHDSFT
RGIEAYVTAE AYAAGSIIQS VDGVREAKLS VEATKDKQLF FDDNAGTLVL PFTFAFLPYN
DEELYQVSPQ QIDVIEHHYR VFERLQKAKA ETEEIGKSAE ATSDALCEMH RQWDNEMMKL
DNGEVEPAAG TASCQSIKNS SEDLELYYIA KMRELILTSS LKVRVEAEND MLTKTLGEVT
ADIVGARLKR PALDMSSKEA SAILDSVHKK TKVFGCNLEN YVKITGREIP EVVESCVKFI
KKFGLEHQGI FRLSGSTTEI NDMKQLFENG RDPLAGLNHW KDINAVAGLL RVYFRELEDP
LFPSSHYQEF IKASLSASVE DGIKEIVTAL NSLPESVVRV MEYLFSFLSL VSEHSDSNKM
DAHNLAVVFG PTLLRIPSEQ DMIAYQSQVN GMIELFIKHC DEIFPGSGEP LPAPLSETEE
SESEEGE
//
