ID A0A2B4RE77_STYPI Unreviewed; 1247 AA.
AC A0A2B4RE77;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Neurogenic locus notch-like protein 2 {ECO:0000313|EMBL:PFX16674.1};
DE Flags: Fragment;
GN Name=NOTCH2 {ECO:0000313|EMBL:PFX16674.1};
GN ORFNames=AWC38_SpisGene19044 {ECO:0000313|EMBL:PFX16674.1};
OS Stylophora pistillata (Smooth cauliflower coral).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC Astrocoeniina; Pocilloporidae; Stylophora.
OX NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX16674.1, ECO:0000313|Proteomes:UP000225706};
RN [1] {ECO:0000313|Proteomes:UP000225706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA Tambutte S., Allemand D., Aranda M.;
RT "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT digitifera provides evidence for extensive differences between species of
RT corals.";
RL bioRxiv 0:0-0(2017).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFX16674.1}.
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DR EMBL; LSMT01000527; PFX16674.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2B4RE77; -.
DR STRING; 50429.A0A2B4RE77; -.
DR Proteomes; UP000225706; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0007399; P:nervous system development; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 11.
DR Gene3D; 2.10.25.10; Laminin; 13.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR PANTHER; PTHR12916; CYTOCHROME C OXIDASE POLYPEPTIDE VIC-2; 1.
DR PANTHER; PTHR12916:SF4; NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1-RELATED; 1.
DR Pfam; PF00008; EGF; 6.
DR Pfam; PF12661; hEGF; 4.
DR PRINTS; PR00010; EGFBLOOD.
DR SMART; SM00181; EGF; 13.
DR SMART; SM00179; EGF_CA; 11.
DR SUPFAM; SSF57196; EGF/Laminin; 4.
DR SUPFAM; SSF57184; Growth factor receptor domain; 2.
DR PROSITE; PS00010; ASX_HYDROXYL; 10.
DR PROSITE; PS00022; EGF_1; 11.
DR PROSITE; PS01186; EGF_2; 10.
DR PROSITE; PS50026; EGF_3; 11.
DR PROSITE; PS01187; EGF_CA; 4.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000225706};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 791..830
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 832..867
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 869..904
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 906..941
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 943..978
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1020..1056
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1058..1094
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1096..1132
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1134..1170
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1172..1208
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1210..1246
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 820..829
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 836..846
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 857..866
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 873..883
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 894..903
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 910..920
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 931..940
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 947..957
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 968..977
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1046..1055
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1084..1093
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1122..1131
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1160..1169
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1198..1207
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1236..1245
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1247
FT /evidence="ECO:0000313|EMBL:PFX16674.1"
SQ SEQUENCE 1247 AA; 136345 MW; 0AA3135B0588B835 CRC64;
MKYTRIVHFL LDEKRKDFPR EFSSDNINNP EIVVQDIPED NTVSVTLLCK VNILNGIASW
RNVTYKIEWF AEGKSLQVET ICGGIPPGSL NEKACPDGTL VSKLPGSKYK IGTWVYPRTT
LLQVQTCSLS IQTITLIPQI PARKNHNGLW PMVSFWLPKE IQLVDQKQCG VLLEGTKNVT
IAIKAACPDG KVTEGLKAIV PQMNIHSNVW NPKTGLPTIW VTVLKPKGDN IQTCTSVTDP
HITALGTNGY FHFMGLGDFI LYKNVERKFE VQTRQWACDG RPFPKGGHNG AGRISCNCGA
VLRDHNDVIE FSCCNDLMIR DKRTPITVRI RSKKCLSPGI SIKRVIPGVN GKYEVLFPSG
AKVVIRRNYW GLDVVIKTPR ATDTKQEGGL CMYPGPYNKY ITDAGFKERL EVGRSYFDTL
PVDVQDSDVT YSSACLCLKE GEGNGGPPSC KSVFKAAFPT LVKEDNMSTL KPQASPSSLC
DRNKRDIHFS DDITDEDIQV YKRTLHLHPR FKRSVANKQV PKENATRYCA TRISDTELGK
LCAKVGVNVQ QLVNTCSVDV ELTGDFSFAS GSVSLLVEQC GVLGAKNLSI PVNGSDERNP
AAEAFVEQVA ELLCPNDCTF NGKCVNGSCV CYKDYTASDC SMSIYQKPEI YRLQEDGLCD
RRKRSCKKGN SCIINGYCFA PNETNPLDWC YQCLPEISTS TWTKRQVNLP PKFSSTSDYF
VVSGETLELP IDVADPENMP VTPSLMQGSP TEASIVDNVL TWKATNEAST KFFLKATDAC
QATSYANITV SLVVCQCKNN GTCVPHPNYP RGSGFYTCNC LPGFTGDKCE TNIDECRSFP
CFRGRCIDRV NTYECDCDPG YVGRDCDTNY DHCSSSPCVN GNCTDYVGTY RCACDPGYSG
LNCTIDVDEC ESSPCAFGAC VDHVDKYTCA CDDGYTGYDC DVEIDECLSS PCIRGTCIDL
VNNYTCNCFA GFTGPNCDIK IENCTEDSCY SNVTCFKKSD RISCGPCPLG LTGDGKNCKD
INYCVSHECR NNGSCVDGIS NYTCNCLDGF AGDRCEIDID NCVNHTCANG GSCVDGVNNY
SCSCRAGFTG DRCGNDIDDC HNHTCQNGAS CVDGVNDYLC ACLVGFTGSK CETDIDDCVN
HTCTNGGTCE DGVNSYSCKC VAGFSGNHCQ NNIDDCRNHS CQNGASCVDG VNDYSCACVH
DFTGQSCETK IDDCVNHTCV NGGTCEDGVN SYSCKCVAGF NGNRCQN
//
