ID A0A2B4RIP1_STYPI Unreviewed; 978 AA.
AC A0A2B4RIP1;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Lethal(3)malignant brain tumor-like protein 1 {ECO:0000313|EMBL:PFX16679.1};
GN Name=L3MBTL1 {ECO:0000313|EMBL:PFX16679.1};
GN ORFNames=AWC38_SpisGene19030 {ECO:0000313|EMBL:PFX16679.1};
OS Stylophora pistillata (Smooth cauliflower coral).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC Astrocoeniina; Pocilloporidae; Stylophora.
OX NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX16679.1, ECO:0000313|Proteomes:UP000225706};
RN [1] {ECO:0000313|Proteomes:UP000225706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA Tambutte S., Allemand D., Aranda M.;
RT "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT digitifera provides evidence for extensive differences between species of
RT corals.";
RL bioRxiv 0:0-0(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFX16679.1}.
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DR EMBL; LSMT01000526; PFX16679.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2B4RIP1; -.
DR STRING; 50429.A0A2B4RIP1; -.
DR EnsemblMetazoa; XM_022948943.1; XP_022804678.1; LOC111341897.
DR OrthoDB; 2905251at2759; -.
DR Proteomes; UP000225706; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd20101; MBT_L3MBTL1-like_rpt1; 1.
DR CDD; cd20102; MBT_L3MBTL1-like_rpt2; 1.
DR CDD; cd20103; MBT_L3MBTL1-like_rpt3; 1.
DR Gene3D; 2.30.30.140; -; 3.
DR Gene3D; 3.30.60.160; -; 1.
DR Gene3D; 4.10.320.30; -; 2.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR004092; Mbt.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR002515; Znf_C2H2C.
DR InterPro; IPR036060; Znf_C2H2C_sf.
DR InterPro; IPR038603; Znf_FCS_sf.
DR PANTHER; PTHR12247:SF131; LD05287P; 1.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR Pfam; PF02820; MBT; 3.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF01530; zf-C2HC; 2.
DR SMART; SM00561; MBT; 3.
DR SUPFAM; SSF103637; CCHHC domain; 2.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 3.
DR PROSITE; PS51079; MBT; 3.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS51802; ZF_CCHHC; 2.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000225706};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT REPEAT 365..469
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 477..574
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 582..677
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT DOMAIN 918..978
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 106..143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 185..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 286..312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 808..840
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..143
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 195..221
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 808..832
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 978 AA; 109021 MW; 1681A51CDB7F4D69 CRC64;
MNGPEAVAVG VTYAKSENFE PQAKKQRLDN DGEQEIDFET SLASKSLRDQ NEISNLCDGK
EQVTAVTHDQ IEPSNESTAI AGSEKKSLIK IMEESISEGN KSIVNGKQQL SNNMGDRKTQ
VFSDSKDMPT MKKEKPSFEE DDPFSALDWK DGIATLPGSN LKFKLTEFGT LEIISTVETE
KGEIQWSTPT ELRKTGSEKT NEKLRDGTRP DDEKDSGIPK KAKTAKNSSP NATDVLCCEV
CGKHGLLQEF SASGRFCGLS CVGVYTGRRN KGREFVRKVK TADGKIVKKK KKGKGKKIGT
AEKPPVAAGA HDSITSVQDA PLMGKFKLKG KGEKHKMKAA KQPISLEPSN LTNGEDVPYD
STKPFVWSEY LAACGAKAVP NIVFKQENPS LDVFPKPNHS FKKDYKLECI DPKHPSYVCV
CTIVKVKGAR LRLHFDGWSE SYDFWTNVDS PFIYPMHWCE RIGQVLHPPR SFTKQEFKWE
KYLKKCGARA APENLFREVQ PTLHGFKIGM KLEAVDRKNP DLICVATVTN VIGNYFLVHF
DEWDDSYDYW CQDDCPYIHP VGWCAENGKK LNPPNDDEVY TFQWEEYLRE TRTVAAPPDL
FKKRPKPSFK PGERMEAVDK RNPSLVRAAR VAALEEYRVK VHFDGWDDIY DDWFDADSTD
LHPVGWCEKT GHPLETPLTT REKISSAACP TPGCKGIGHV KGAKYSTHHS TFGCPYSLQN
LNKDSCLVDR LSNNSMTEES DWSYASKQKT TGFKEVKPEI PSSPIVEGVC PTPGCDGLGH
VTGHWKTHYT LSGCPNNEAN QGKIFSKHTS KSPVNKKNPH LSPTSNSPPP VISGTKAPVG
GSIISTRSSA RKVFVKEEKH QGIRQKYADK AVQHVTPFSF PWPLGSQFSM MGLSELKAAI
SLENESVASN ERQRIIKWTV DDVMSHVRSL GCLEQAKIFG DELIDGEAFL LVTQNDIVNI
LKIKLGPALK IFNTIPKH
//
