ID A0A2B4RLH5_STYPI Unreviewed; 2854 AA.
AC A0A2B4RLH5;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Fibroleukin {ECO:0000313|EMBL:PFX18451.1};
DE Flags: Fragment;
GN Name=FGL2 {ECO:0000313|EMBL:PFX18451.1};
GN ORFNames=AWC38_SpisGene17174 {ECO:0000313|EMBL:PFX18451.1};
OS Stylophora pistillata (Smooth cauliflower coral).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC Astrocoeniina; Pocilloporidae; Stylophora.
OX NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX18451.1, ECO:0000313|Proteomes:UP000225706};
RN [1] {ECO:0000313|Proteomes:UP000225706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA Tambutte S., Allemand D., Aranda M.;
RT "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT digitifera provides evidence for extensive differences between species of
RT corals.";
RL bioRxiv 0:0-0(2017).
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01172}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFX18451.1}.
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DR EMBL; LSMT01000410; PFX18451.1; -; Genomic_DNA.
DR Proteomes; UP000225706; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR CDD; cd00057; FA58C; 1.
DR CDD; cd00063; FN3; 3.
DR CDD; cd00087; FReD; 1.
DR CDD; cd06263; MAM; 1.
DR Gene3D; 2.60.120.200; -; 7.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.90.215.10; Gamma Fibrinogen, chain A, domain 1; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR036056; Fibrinogen-like_C.
DR InterPro; IPR014716; Fibrinogen_a/b/g_C_1.
DR InterPro; IPR002181; Fibrinogen_a/b/g_C_dom.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR000998; MAM_dom.
DR InterPro; IPR001759; Pentraxin-related.
DR InterPro; IPR006571; TLDc_dom.
DR NCBIfam; NF040941; GGGWT_bact; 1.
DR PANTHER; PTHR19143; FIBRINOGEN/TENASCIN/ANGIOPOEITIN; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00754; F5_F8_type_C; 2.
DR Pfam; PF00147; Fibrinogen_C; 1.
DR Pfam; PF00041; fn3; 3.
DR Pfam; PF13385; Laminin_G_3; 5.
DR Pfam; PF00629; MAM; 1.
DR Pfam; PF07534; TLD; 2.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00231; FA58C; 2.
DR SMART; SM00186; FBG; 1.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00137; MAM; 1.
DR SMART; SM00159; PTX; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 7.
DR SUPFAM; SSF56496; Fibrinogen C-terminal domain-like; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 2.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS50022; FA58C_3; 2.
DR PROSITE; PS51406; FIBRINOGEN_C_2; 1.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS50060; MAM_2; 1.
DR PROSITE; PS51828; PTX_2; 3.
DR PROSITE; PS51886; TLDC; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Reference proteome {ECO:0000313|Proteomes:UP000225706};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022530}.
FT REPEAT 80..114
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 115..136
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 656..866
FT /note="Fibrinogen C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51406"
FT DOMAIN 1111..1271
FT /note="TLDc"
FT /evidence="ECO:0000259|PROSITE:PS51886"
FT DOMAIN 1289..1442
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT DOMAIN 1444..1603
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT DOMAIN 1728..1882
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT DOMAIN 2561..2658
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2660..2754
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2758..2854
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT NON_TER 2854
FT /evidence="ECO:0000313|EMBL:PFX18451.1"
SQ SEQUENCE 2854 AA; 322015 MW; 23D2BD9DDAFD3C98 CRC64;
MAETTGEVDF DDIVCKGKEL WTALRNNPTD KQRVLELLRN GAKPNFRDPD NSQIIFQIKE
TLEVNLNPPN PVSALLEGYI NWTPLHFVVS DKEGDVELID MLLEHGAETN FGDSYNLTPL
HLAAEKGYLK TVEKLLTNPH SKADRTKRSI AGKETALDIV ERKLREPLAD VVDKEEEEAR
RKELEKVASY LRNYQTAVTV SHGGSSDVTI IPQQDHEFSL EFPSRQRSQL AYSTVRINGD
KDIDAFTICL WLKPSTLGSD LGLLRYFDEA GSNVYFALRL GDVGQLWISI HGEDRELDIM
PQIQYGVWHG LCVTWNKHGG HFMIYYDGRL IRSENGLKSG NSFPSNETFT LGIGAEEKFN
YTGMVGHVNI WPSVLEHSLL SVLSSKCGVE RGGLVSWPQF RKDLRGVDVH TKESCPFNEV
QITHEENHWK LDGDDKDLNP KYSAVFLEGR LDGHKAVYLD QTMSYIEAPR LSLGTAFSIT
CWVKLLYSTP VYRPILSVET NSTEKFSIGF NADSQLLLDK WSQGVYNITK SYASLPANQW
IHVAVTFAQE GVLSFFFDGM KNLSVAGVWQ GPRSGAFEIG RYKNVSEDKH RHFHGFLSDL
YVFSKNLTAE EIGRLMGRSY PCTLSEWSSD AKLTPHQTPR KKYRHKSCPG IGECKEVRKW
KPADCREVLL SGCKTSAKYT ISPLNNHEEF EVFCDQETQG GGWTVIQQRI NGSVSFNRTW
DEYKAGFGVM GVQLEMWLGN ERIHSLTTQK TEILIELTAF DGTKGFAYYS HFHVAGEDLW
YQLSVGGFSG NIPDKLVLHD TFNFSVTKCG AATSSSGWWF TPSCGEALLN SEYGHDTGSM
MWSDFPVAGA HKGKIKKSTM KIRRTEVRPP TVPRQMNLLR YVVQDGNFSM GLKPYGKEYK
IILSIWPSTR GFNKQVKYPS LDGSWRHVCT SWTNVDGRGA IYIDDTQTPF LGIGNGTKFT
GGGKVVIGST HVVEPPLLGL EITYMNLWDK VLSTVSIENL AHSCGAEAGN VLQWSLFAAM
SVGNVQVVPS SACRAKEMYY WNFNQSNSLE SFDGNKNHRA ELTGGKISPG QKYLVIEDQG
KFLAENLSSE LSGENGFTVS FSAGQTVLAS EILRNDFKSL EVLHRAFPDF IRDHATWKRC
YFADQSSWST AEFHTKCDYK GPTLTIVRVR EYVFGGFVEN SWGGKPSNIG HQIEGFLFSL
SNPFDLAPRI LPIQQGKASG RTNPHLGPSF GERDLELFED KHGRIMGYSR LGASFDLMSV
SLSSYEAWFY LAGSQHFYPD QVEVFYYHVP STPLGLENQI LPDNYLSNSS QLNSSSGPHL
ARLNEQRDSK AWCSAGPNEW LQVFLGKQYT LTHMALQSIG GGVDVTELKV QYEKTRDGIK
WKYYSKEIDG KEMLKVLRFN FPSAGFVKKE AFIPPFQAVK VRFLLTETRV QCIKMELYFY
DAGCSQPHGI ENRTVVPDEK LTASSTEVSD EYKQGYFWPN IGRLNHDKEG AHSWGPYKHP
VHLFKGIWFQ VDLKEETEVT CIATQGRPTN IQWPTKYQLA YSSEGNDWKY FEDINGVKKF
DANSDQHMAV TNWLVPSIYG RFFRVYITRC NIACRLRMEL YGRRDPTNNI YWSKNGLSFT
VRRGRYHIFF AKENHRWEIR HPLIVNQWFE ATIAWKLQDG LKFYVNGNLV ASDKIPVRRN
FFPAKEPFKL LIASMENGGG WSRAISIDDV AVWGKAMSKE EINRKSEVHF DFDDNSRDWE
SLVDGTNGWT LLQGCTKTSG TGPCDDVSRG GRYIYFDAAQ SKEKARFSTP SSIHSYNCLK
FHYHMAGTHT GRLNVYATDI RGKEQLLWRL FGEQKNTWRK ASIPVNDIHP QYQVVFEAVR
GPGYLGDIAL DQIAFTRESC VFSPSSAMPH NSHRSGVGQV GDNSSYDLQF WRKNSADIVK
SVLPTLTPNS SFTASLWLKT SVKSTLIVFS IGQIDSFLQL RLEPAGWLSL CSKDKCNTNN
GSISQVINDG CWHHVTVVWH SSSKSWTVFS DGVNRGKQTE EKWQKSTFSL SGTLFIGKEQ
IQGSSRFFSG RITQFNMWNH ELEEKDITVL ARNCANLSRT CTAVGQFTYQ SPCTGLSTNY
RADTKAFIFS LNYTSDGTLF KKEISKESSA LATYSSPYTG PTFGESPFDF QIGIDGDLKR
GTSQHSVSYK EEEDSSKSNL ETVLAGASSF NVNDVEVLYR AQGASLCSNR CPFYHYCDEI
TGICRCRNKN PALCQLVKFY EDSSHFWLLE SMDDIKDLRT PGWGQSKGGV SSFGDGLVTD
GVNGEVILNH EGDTCATKSA EAHCDDSGFT VSLSLKPSYK AGGERQTFFK SRGKFVVYQE
RQKKSLIIRV RRSAKYCLKE IAMPEKIWSH LAFTYQPSQP RTLTVYRNGR KIDKFIRDEG
CEVDGEPEFS STSMSLGSEG GLFAKAHYYL IAIWGQVLSE ERITQIYRGI QGSVPLRCRV
VARIKNQLWN EDLTSPETDP YRAMTNEIIS NVTRFYEGIR VTVTVNEFRN GSVIADFTII
YNVSDYKLIE RLQQNISSTG FLYNMPLEVE EFTAENVPEV APTNISVLRV EDTSIHIRWN
SLSLPPSISA IFQGYKVFIR SVGRADVIVT TVTVNDLVNF VTIKGLESLV TYNLTVAGYT
LSGVGRESES FSVTTPLDDP PEDISVERVT SNCVQIKWGG LPPEKLAAFD GYRVFYALFS
HPTFSLNTTV NSSTHRVEIC SLESSMKYKF YVQRILRKDV GNASDVKYFT TEIVMRLAPT
NVTCRNTSST SIEVHWAPPS VEVNSLEIIG YDLHFRPHGL ATELWSTLLA CNRTLSATIK
SLEKYTEYDI RVTIFITNGR GNFSEIVRCF TDED
//
