ID A0A2B4RMM7_STYPI Unreviewed; 425 AA.
AC A0A2B4RMM7;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Homer protein-like 2 {ECO:0000313|EMBL:PFX17492.1};
GN Name=Homer2 {ECO:0000313|EMBL:PFX17492.1};
GN ORFNames=AWC38_SpisGene18174 {ECO:0000313|EMBL:PFX17492.1};
OS Stylophora pistillata (Smooth cauliflower coral).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC Astrocoeniina; Pocilloporidae; Stylophora.
OX NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX17492.1, ECO:0000313|Proteomes:UP000225706};
RN [1] {ECO:0000313|Proteomes:UP000225706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA Tambutte S., Allemand D., Aranda M.;
RT "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT digitifera provides evidence for extensive differences between species of
RT corals.";
RL bioRxiv 0:0-0(2017).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Postsynaptic density {ECO:0000256|ARBA:ARBA00034105}. Synapse
CC {ECO:0000256|ARBA:ARBA00034103}.
CC -!- SIMILARITY: Belongs to the Homer family.
CC {ECO:0000256|ARBA:ARBA00023606}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFX17492.1}.
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DR EMBL; LSMT01000469; PFX17492.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2B4RMM7; -.
DR EnsemblMetazoa; XM_022947658.1; XP_022803393.1; LOC111340765.
DR OrthoDB; 5490527at2759; -.
DR Proteomes; UP000225706; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.
DR GO; GO:0035256; F:G protein-coupled glutamate receptor binding; IEA:InterPro.
DR GO; GO:0007216; P:G protein-coupled glutamate receptor signaling pathway; IEA:InterPro.
DR CDD; cd01206; EVH1_Homer_Vesl; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR045027; Homer.
DR InterPro; IPR044100; Homer_EVH1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR000697; WH1/EVH1_dom.
DR PANTHER; PTHR10918; HOMER; 1.
DR PANTHER; PTHR10918:SF5; HOMER, ISOFORM E; 1.
DR Pfam; PF00568; WH1; 1.
DR SMART; SM00461; WH1; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50229; WH1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000225706};
KW Synapse {ECO:0000256|ARBA:ARBA00023018}.
FT DOMAIN 41..153
FT /note="WH1"
FT /evidence="ECO:0000259|PROSITE:PS50229"
FT REGION 153..231
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 239..308
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 336..411
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 156..217
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 425 AA; 46963 MW; 4E0AB591C524493B CRC64;
MFKQVRSRLS LSHKEPLEIV FDPPSQFTDL NGAAMDYQHN LPRPQEQPVF STRAHVFQID
PATKKSWLPC SKQAVTVSFY YDPNQGTHRI ISVDGTKVII NSTVLPNMTF TKTSQKFGQW
SDPRANTVFG LGFPSEAELN KFAEKFKEAK GGSKAAVGNN NGNSNSSPAP VNAVTTNGTS
SGSVNGTAES PHSTPGVGHK SPSVKSNSSA SSGEDESKES AGISHKPIGN TESHLKYEND
RLKMALAQSS ANAKKWEAEL TTLKNNNARL TAALQESTAN VEEWKKQLNA YKEENGKLRK
KVHELESSDQ LSEKYNSLTQ EKLTLDGRVI QLESMIRQKD EDITSLRQAK AELTNQNQTL
QLDNERLQLK TEEMSLHMNE TALNETRVKE LTELQQELAN KVEEMSALST RLATSLEMAP
PLTES
//
