ID A0A2B4RNG2_STYPI Unreviewed; 1824 AA.
AC A0A2B4RNG2;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Unconventional myosin-Va {ECO:0000313|EMBL:PFX17877.1};
GN Name=MYO5A {ECO:0000313|EMBL:PFX17877.1};
GN ORFNames=AWC38_SpisGene17781 {ECO:0000313|EMBL:PFX17877.1};
OS Stylophora pistillata (Smooth cauliflower coral).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC Astrocoeniina; Pocilloporidae; Stylophora.
OX NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX17877.1, ECO:0000313|Proteomes:UP000225706};
RN [1] {ECO:0000313|Proteomes:UP000225706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA Tambutte S., Allemand D., Aranda M.;
RT "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT digitifera provides evidence for extensive differences between species of
RT corals.";
RL bioRxiv 0:0-0(2017).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFX17877.1}.
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DR EMBL; LSMT01000444; PFX17877.1; -; Genomic_DNA.
DR STRING; 50429.A0A2B4RNG2; -.
DR EnsemblMetazoa; XM_022947074.1; XP_022802809.1; LOC111340253.
DR OrthoDB; 1094820at2759; -.
DR Proteomes; UP000225706; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd15470; Myo5_CBD; 1.
DR CDD; cd01380; MYSc_Myo5; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 3.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.20.240.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR002710; Dilute_dom.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR036103; MYSc_Myo5.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF289; UNCONVENTIONAL MYOSIN-XIX; 1.
DR Pfam; PF01843; DIL; 1.
DR Pfam; PF00612; IQ; 4.
DR Pfam; PF00063; Myosin_head; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM01132; DIL; 1.
DR SMART; SM00015; IQ; 6.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF50084; Myosin S1 fragment, N-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR PROSITE; PS51126; DILUTE; 1.
DR PROSITE; PS50096; IQ; 5.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Coiled coil {ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000225706}.
FT DOMAIN 8..59
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 68..760
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 1508..1779
FT /note="Dilute"
FT /evidence="ECO:0000259|PROSITE:PS51126"
FT REGION 613..632
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 639..661
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT COILED 967..1158
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1189..1269
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1293..1377
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 162..169
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1824 AA; 211420 MW; F1EF1527A30BAEDC CRC64;
MTTLELYTKG ARVWIPHDQV IWIGGELTKD LKEDGILEIE LEDGNEITLD VSKGKQNLPP
LRNPEVLVGE NDLTTLSYLH EPAVLYNLQV RFLQSNAIYT YCGIVLVAIN PYQQLPLYGP
DIISAYSGQS MGDMDPHIFA VAEDAFRAMA RDGLNQSIIV SGESGAGKTV SAKYAMRYFA
SVGGASTETQ VEKKVLASNP IMEAIGNAKT IRNDNSSRFG KYLEISFDKN YHIIAAHMRT
YLLEKSRVVF QAPDERNYHI FYQLCAACDT PELKDLRLAH QDNFYYLNQG ECAYVDEVDD
AEGFEEMREA MDLVGIMNDE QLMIFRILAG ILHIGNIDIQ PESDEESTID DKDFHLAVAA
DLLGIDRSQF KKWLCNRKIV TVQEVLIKPL NAEEADFGRK AISKHIYSQL FKWIVQCINN
SLSSGVKQHS FLGILDIYGF ETFEENSFEQ FCINYANEKL QQQFTQHVFK LEQDEYVKEE
IEWSFINFYD NQACIDLIEA KLGILDLLDE ECKMPKGADS SWIQKLYKHH MKKEHFSKPR
LSQTAFIVHH FADDVQYEIR GFVEKNRDSV NQEHLAILKA SEYELVARVI DCAHNYEMVG
DLFTENEAHM MPRKRTTSRT GKNISKSKRS VGSEFRESLS KLMETLNSTV PHYIRCIKPN
DRKAPFEFNP QRSIQQLRAC GVLETVRISA AGYPSRWSYY EFFNRYRMLV KFEVINRRKP
RATIELILKT YIKDPDKFQM GKTKIFFRAG QVAYLEKLRS DKLRDSCIMI QKNFRCWREH
RLYLRMRRSA ILIQAWVRGY LARRLAQDLR EKKAAITIQR YYRGYVCRKQ FVTIRAAVII
IQCFTRGMFA RRLRMQLLHE AKTKIIQRCW RRYKARKNYR NYKKTIIYLQ SCVRRMIARR
ELKQLKIEAR SVEHYKKLNV GMENKIIHLQ QRLDAQVKEK EQAMVAGREL EATRKELEHA
KQWKGQFEST QSKMLELELV IKELREELNT VIVEKDETEE RAKTEKEELE EINKRLREEL
TNLTEELAEK EAISDREVSL RDEIINQSLE AQRQQLLAEF EAERSNHQRV LRDYDRLEQR
YQNLQDEMEI EKFSPVAKRE SDGLITASGS ENSLEDAVER EQQQNENAEA GMKNSKLVRG
LRKRIRELED KLLESEQVQA NGDIPSITVE TTSEQKLPSE NQVMESEKFQ QVLHEREQME
QEKSSLEQEN KKINSELELL RKLVSQRNID KEAEWNMINE KMDEISADRE QIENEKNRLR
DELVNMASVA TDMQNAEELL QTNPDENAYV LQAKSLKKAN NVLQNELQDL IQKEKELRAA
NEKLWKEKAQ LQMGRGPSLS SMDGNFNKEV SRLVTENVEL REQVEKLEAE LEEYKKGGTT
ALTPFRGRAQ SWRGEVEQKR RAQSFLSGQE PKAGKLVMRH AGLLRKSSHA HKEGDLLPPL
PQLRQQKIRG MIEFSSEDED KVIKFLITDM NPKSMADATP GLPAHILFMC IRHCDHVNDD
RRMQSLLTSS INSIRKVVKK NPNNLDILAF WLANTSRLLH DMKQYSGDKA FQVHNTPEQN
QHCLKNFDLT EYRQVLSDLA IHVYQDLVKC IWEAVQNMIV PGMLEYESIP GVSSSKPFGG
RSKAHADITV KSITKMLSNF LAILNAHCVD PEIIKQVFRQ LFYYIGANMM NNLLLRKDMC
HWSRGMQIRF NLSQLEDWVR LNQLEGSGIV EALENVIQAT QLLQVNKKTL EDVDAICEVC
SSLNTLQVQK ILSMYTPANE YEARVPSSVI RAVVERGHNK TDPMFLMTDT AYIYPFTLPF
TPSAVSLDSL TIPDNLNLDF LRVV
//
