ID A0A2B4RW60_STYPI Unreviewed; 804 AA.
AC A0A2B4RW60;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=BTB/POZ domain-containing protein 2 {ECO:0000313|EMBL:PFX21851.1};
GN Name=BTBD2 {ECO:0000313|EMBL:PFX21851.1};
GN ORFNames=AWC38_SpisGene13651 {ECO:0000313|EMBL:PFX21851.1};
OS Stylophora pistillata (Smooth cauliflower coral).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC Astrocoeniina; Pocilloporidae; Stylophora.
OX NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX21851.1, ECO:0000313|Proteomes:UP000225706};
RN [1] {ECO:0000313|Proteomes:UP000225706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA Tambutte S., Allemand D., Aranda M.;
RT "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT digitifera provides evidence for extensive differences between species of
RT corals.";
RL bioRxiv 0:0-0(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFX21851.1}.
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DR EMBL; LSMT01000260; PFX21851.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2B4RW60; -.
DR Proteomes; UP000225706; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005230; F:extracellular ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR CDD; cd19049; LGIC_TM_anion; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.70.170.10; Neurotransmitter-gated ion-channel ligand-binding domain; 1.
DR Gene3D; 1.20.58.390; Neurotransmitter-gated ion-channel transmembrane domain; 1.
DR Gene3D; 2.60.120.820; PHR domain; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR006028; GABAA/Glycine_rcpt.
DR InterPro; IPR006202; Neur_chan_lig-bd.
DR InterPro; IPR036734; Neur_chan_lig-bd_sf.
DR InterPro; IPR036719; Neuro-gated_channel_TM_sf.
DR InterPro; IPR038050; Neuro_actylchol_rec.
DR InterPro; IPR006029; Neurotrans-gated_channel_TM.
DR InterPro; IPR038648; PHR_sf.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR45774:SF3; BTB (POZ) DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR45774; BTB/POZ DOMAIN-CONTAINING; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF02931; Neur_chan_LBD; 1.
DR Pfam; PF02932; Neur_chan_memb; 1.
DR PRINTS; PR00253; GABAARECEPTR.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF90112; Neurotransmitter-gated ion-channel transmembrane pore; 1.
DR SUPFAM; SSF63712; Nicotinic receptor ligand binding domain-like; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000225706};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 597..619
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 631..650
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 662..684
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 783..802
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..82
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 804 AA; 92050 MW; 7010A43A5C172BD0 CRC64;
MYRNPLLADV HFTVTDGQGS SSPKVKIPSH KFILAVSSPV FYKMFYGGLK EPSDYIDLPD
CDSEGFLEFL HFIYCDEVEL TGSCVLQVLY LAKKYMIPAL EIRCRSFLRE NINAENVLDL
LPVVEKMEES QLNDVCWNCI DKHPRKVLDS AQDSFLEDND LLVSMLKRDT LDIKEVEIFQ
VVNRMAESIC VKRGITPTGK EKRRIIGEKL LTLIRFPIMP EKEFAEHVTD TKILSDSEVV
LMFMYFNLNR KPGKFSYIPR CLNNANVQRC KRSRTCFENL NYNGYQGCCC NDTDFKDSVS
LTVNIPIALG GIRLLGSKGR EYIVQLKLNG QFIMNERSLT AGEKSWNSVL VGYDIIFGRY
HLLEPNQPYV FKIFVKGPIC EHVAKTVFAK EEKRAEMVIG RKLSMPAGYL KFYFKQRIVQ
CEDDVVTNFF SDYDKAVRPG FEQAKATIVD VDIYVESFGN IEEANMEYRV YTYFRQRWTD
GRLAGKLNRT LTIKGGDIEN IWVPDPYCYN ARESNMMMPD EETHSSVTVR PSGDVLYSRG
YTTEDIVFKW NTTEIDVGAK AMAQFVYEGS KLSSDINVFS IGNYSTITVT FSFRRRIGYY
IIQVYFPDIF VVALSWIVFW MDKDDTGNRM ALGITTILTI MFLLGSLNGT LPKVSYAKAL
DWYLLISFAF VFFSMVECMI VFVLNLSANE DKEKIICKVT EKPLARKISQ SIKSAIGTNK
GANSSAANRH VNFVQDYADD DLEMADQARK ADKFFVDDSA LKDFIGKSKK ETAADCVDKL
SRYFFPVLFI TFNVAYWVYF TLLG
//
