ID A0A2B4RXY3_STYPI Unreviewed; 1106 AA.
AC A0A2B4RXY3;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Multiple epidermal growth factor-like domains protein 10 {ECO:0000313|EMBL:PFX21643.1};
GN Name=megf10 {ECO:0000313|EMBL:PFX21643.1};
GN ORFNames=AWC38_SpisGene13853 {ECO:0000313|EMBL:PFX21643.1};
OS Stylophora pistillata (Smooth cauliflower coral).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC Astrocoeniina; Pocilloporidae; Stylophora.
OX NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX21643.1, ECO:0000313|Proteomes:UP000225706};
RN [1] {ECO:0000313|Proteomes:UP000225706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA Tambutte S., Allemand D., Aranda M.;
RT "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT digitifera provides evidence for extensive differences between species of
RT corals.";
RL bioRxiv 0:0-0(2017).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFX21643.1}.
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DR EMBL; LSMT01000268; PFX21643.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2B4RXY3; -.
DR STRING; 50429.A0A2B4RXY3; -.
DR Proteomes; UP000225706; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR CDD; cd00055; EGF_Lam; 1.
DR Gene3D; 2.10.25.140; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 4.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR011489; EMI_domain.
DR InterPro; IPR002049; LE_dom.
DR InterPro; IPR042635; MEGF10/SREC1/2-like.
DR PANTHER; PTHR24043:SF8; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24043; SCAVENGER RECEPTOR CLASS F; 1.
DR Pfam; PF12661; hEGF; 4.
DR Pfam; PF00053; Laminin_EGF; 6.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00181; EGF; 16.
DR SMART; SM00180; EGF_Lam; 13.
DR PROSITE; PS00022; EGF_1; 12.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 6.
DR PROSITE; PS51041; EMI; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000225706};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 824..848
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..57
FT /note="EMI"
FT /evidence="ECO:0000259|PROSITE:PS51041"
FT DOMAIN 56..87
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 95..130
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 143..173
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 181..216
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 224..260
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 763..793
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 1024..1106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1027..1049
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1079..1094
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 77..86
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 120..129
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 163..172
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 206..215
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 250..259
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 783..792
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1106 AA; 119411 MW; 9ABCABC2623FE637 CRC64;
MSWKKKSTTK CGWLGWKRCT VYRTVYGVSY RTLTRHAFKP VYSCCLGWRQ SGNGCPFAIC
KNPCVNGTCT QPDKCSCNAG YYGLVCDREC PSHKWGPHCR HDCKCKNGAQ CDSLTGQCAC
TPGWKGQQCE QPCDQGFYGI KCQQRCDCLN GGTCEPATGN CTCAAGFQGT RCELLCDKGW
YGKNCAQKCT CLNGGKCDHI TGKCNCAAGW QGDLCSSKCP DGKYGDNCSQ TCINCLNGAV
CNHVNGSCTC APGYQGHRCG DMCPSGSYGK FCAEECRCKN GTCSPVDGSC NCTVGYTGMY
CDQPCSAGSA GQDCTKHCNC TIHGTCNPFT GKCQCQPGFQ GMHCEKECST GFFGPLCKGK
CQCLNNATCD KKDGTCDCLQ GWIGVHCDNP CPAGYYGKNC QSNCGCQNGG SCDLVDGKCT
CVNEWQGESC DIMCGNWTFG VNCRNSCLCN QTQTERCHRI NGKCLCKNGF TGLYCNEQKR
CPVGYYGCPV GYYGNNCDKS CHCNHNAPCD VITGSCDCPA GFMLPNCFNN CPLGRFGIKC
KETCKCQNGA SCDPVDGTCG CTSGWQGTFC EQGCPDGWYG PGCNSSCDCL HDSSCHHVTG
KCTCNAGWKG VKCNEPCDSG YYGLGCQTIC QCYKDNTISC DPIDGRCSCE PGWTGQECTL
FCPRRKFGAK CLQDCKCVEE STENCDHVTG ACTCLEGWTG DTCDKTCSAG YYGYKCKKEC
ECRMPNMAKE CDHRNGECHC EPGFTSQYCN QTCPASSYGF NCENKCLCEN NSTCNNTFGY
CHCLTGFQGK FCEEVVFTKS TVVPSPGNNS SNSGRSTGDG SASVVTPVMI AVAVAMVAII
LIIVLVYLGR KRVFISRTGN GLSMKKLVRS PRCSKSVDRV DDEGNYTEDH VSLNPIYGHL
SNPDSTPLDV VQSPGNRPTS MTIKSVNNPN YENTLTLRTD YDKRTSNPIY QTATELDNPL
YNTGADINPL YEAGPSGSVS RGSGSLADMN PLYQSATSYR SQCDFNPLYE SSSDMSPLYE
AAVPAAEKKN SKARRRADSR TKKEDKVPIM DNAPSCWSTE DEDGLGVSNR GVDVTFNELY
GSVEQTSSSP TENEPGATPL PPSTAC
//
