ID A0A2B4RZD1_STYPI Unreviewed; 749 AA.
AC A0A2B4RZD1;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Carnitine O-palmitoyltransferase 1, liver isoform {ECO:0000313|EMBL:PFX22159.1};
GN Name=Cpt1a {ECO:0000313|EMBL:PFX22159.1};
GN ORFNames=AWC38_SpisGene13330 {ECO:0000313|EMBL:PFX22159.1};
OS Stylophora pistillata (Smooth cauliflower coral).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC Astrocoeniina; Pocilloporidae; Stylophora.
OX NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX22159.1, ECO:0000313|Proteomes:UP000225706};
RN [1] {ECO:0000313|Proteomes:UP000225706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA Tambutte S., Allemand D., Aranda M.;
RT "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT digitifera provides evidence for extensive differences between species of
RT corals.";
RL bioRxiv 0:0-0(2017).
CC -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005232}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFX22159.1}.
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DR EMBL; LSMT01000249; PFX22159.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2B4RZD1; -.
DR STRING; 50429.A0A2B4RZD1; -.
DR EnsemblMetazoa; XM_022940398.1; XP_022796133.1; LOC111334607.
DR Proteomes; UP000225706; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR InterPro; IPR000542; Carn_acyl_trans.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR039551; Cho/carn_acyl_trans.
DR InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR22589:SF112; CHOLINE_CARNITINE ACYLTRANSFERASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00755; Carn_acyltransf; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000225706};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:PFX22159.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 52..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 139..729
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
FT ACT_SITE 434
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-1"
SQ SEQUENCE 749 AA; 85658 MW; 201A3AF92949C899 CRC64;
MAEARAAVTR PDVHLHAEGT SKSEAEVELL KSTFLSLKRC AFRTRRQIAN GLWPTTWSNL
LGAVVVIAAL LYATDFYKLS SLQPFTAVIW KISSLFAGSV YYENPRSQSK LTLLWGAMVK
LCAGHYPKLY SYQNSLPRMP VPNLNETCKG LLRSVKPILS EEEYKKMETL AKDFEKNLGP
KLQFILKLKS WWAPNYHTDW WEKYVYCMGR SPLPINSNYY CLDQHWHPTY VQASRAATMS
YLILKYYQEI ETEHLEPLLI RKTIPICMSQ YERTFKTTRI PKEDVDEIVH FEHDEHEHIA
VFCGGNCYML PVTDKGKFIS VLDLESQFEW IVADAKHSDV TKDQPDGSVP ALTALPRTEW
AKIRKEYFSE SLNRSTLEAI EEAMFVVILD ENSFTDLSER AKYLLHGDGR SFWFDKSFCL
MVFSDGRCGI NAEHAWADAP VIGHMLEYAL TFEYIYRTYN DKGKCTPIGG AHRSASLRTH
NLQKPSRLYW DITPKLAHII EDAVKFAQKN NEDIQHKVIV HDAFGKGFIK SVKISPDAFI
QLALQLAYYR DSNGRHPLTY ESSMTRLYLQ GRTETVRSLT IEAKDFVLAM LDDTVPPEEK
YKLLHKAADL HAKQYKDCMN GKGIDRHLFA LFVVCRGQGY ESEFLKSALT LPWTLSTSQQ
PQQQMAGTHF SVTEPELTHL ISPGGGFGPV ADDGYGVSYM VPDDHRIFFH ISSKISSKES
NSDRFVKLLF ESLSDIKTLH DTVRAKKAK
//
