ID   A0A2B4S2E9_STYPI        Unreviewed;       770 AA.
AC   A0A2B4S2E9;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   22-FEB-2023, entry version 13.
DE   SubName: Full=Cullin-1 {ECO:0000313|EMBL:PFX23219.1};
GN   Name=CUL1 {ECO:0000313|EMBL:PFX23219.1};
GN   ORFNames=AWC38_SpisGene12229 {ECO:0000313|EMBL:PFX23219.1};
OS   Stylophora pistillata (Smooth cauliflower coral).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC   Astrocoeniina; Pocilloporidae; Stylophora.
OX   NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX23219.1, ECO:0000313|Proteomes:UP000225706};
RN   [1] {ECO:0000313|Proteomes:UP000225706}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA   Tambutte S., Allemand D., Aranda M.;
RT   "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT   digitifera provides evidence for extensive differences between species of
RT   corals.";
RL   bioRxiv 0:0-0(2017).
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PFX23219.1}.
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DR   EMBL; LSMT01000214; PFX23219.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2B4S2E9; -.
DR   STRING; 50429.A0A2B4S2E9; -.
DR   EnsemblMetazoa; XM_022938775.1; XP_022794510.1; LOC111333231.
DR   OrthoDB; 5474206at2759; -.
DR   Proteomes; UP000225706; Unassembled WGS sequence.
DR   GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016157; Cullin_CS.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF169; CULLIN-1; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01256; CULLIN_1; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000225706};
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   DOMAIN          414..641
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
SQ   SEQUENCE   770 AA;  89362 MW;  3D9B52F3DBE3F987 CRC64;
     MNTMASRTQN PHGLRQITLD EIWDDLKEGI QHVYKQQSMS KPRYMELYTH VYNHCTSVHQ
     QSQSRVPKQK KAPNQGGAQF VGLELYKRLK DFLRTYLIGM QKDGADLMDE SVLKFYTHRW
     EDYRFSSKVL NGVCAYLNRH WVRRECDEGR KGIYEIYSLA LVTWRENLFR PLNRQVTNAV
     LRLIERERNG ETINTRLVSG VIQCYVELGL NEDDPSARGP TLSVYKASFE SVFLEDTERF
     YTTESTEFLR ENPVTEYMKK AEARLLEEQR RVQVYLHEST QDELARKCEH VLIEKHLDIF
     YSEFQNLLDD DKNEDLGRMY NLVARIPDGL GQLRTLLENH ITNQGLNALE KCGDQAFNDP
     KVYVETILEV HHKYNALVLT AFNNDAGFVA ALDKACGKFI NNNSVTKQAH SSSKSPELLA
     RYCDSLLKKS SKNPEEAELE DILNSVMVVF KYIEDKDVFQ KFYSKMLAKR LVQHNSASDD
     AEASMISKLK QACGFEYTSK LQRMFQDIGV SKDLNDKFKA HLLNTESLDL DFTIQVLSSG
     SWPFQQSAPF SLPAEMERSH QRFTTFYSSQ HSGRKLHWVY HMSKGELVTN CFKNRYILQA
     STYQMGVLLM FNNSESLTME QIQEQTQLKT DILSQVLGIL LKSKLLVCET SDDGSNIDRQ
     TSVSLNFGYK SKKLRVNINV PMKTEQKQEQ EQTHKYIEED RKLLIQAAIV RIMKMRKMLK
     HQPLLAEVLS QLSSRFKPRV PVIKKCIDIL IEKEYLERVE GEKDTYAYLA
//