ID A0A2B4S4P7_STYPI Unreviewed; 350 AA.
AC A0A2B4S4P7;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Integrator complex subunit 12 {ECO:0000256|ARBA:ARBA00016814};
GN Name=INTS12 {ECO:0000313|EMBL:PFX24366.1};
GN ORFNames=AWC38_SpisGene11016 {ECO:0000313|EMBL:PFX24366.1};
OS Stylophora pistillata (Smooth cauliflower coral).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC Astrocoeniina; Pocilloporidae; Stylophora.
OX NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX24366.1, ECO:0000313|Proteomes:UP000225706};
RN [1] {ECO:0000313|Proteomes:UP000225706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA Tambutte S., Allemand D., Aranda M.;
RT "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT digitifera provides evidence for extensive differences between species of
RT corals.";
RL bioRxiv 0:0-0(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the Integrator subunit 12 family.
CC {ECO:0000256|ARBA:ARBA00006009}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFX24366.1}.
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DR EMBL; LSMT01000178; PFX24366.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2B4S4P7; -.
DR STRING; 50429.A0A2B4S4P7; -.
DR EnsemblMetazoa; XM_022936893.1; XP_022792628.1; LOC111331725.
DR Proteomes; UP000225706; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15501; PHD_Int12; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR039054; Int12_PHD.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13415:SF2; INTEGRATOR COMPLEX SUBUNIT 12; 1.
DR PANTHER; PTHR13415; NUCLEAR FACTOR-RELATED; 1.
DR Pfam; PF00628; PHD; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000225706};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 174..231
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 35..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 236..283
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..64
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 350 AA; 38835 MW; 9C3B97383E0E9B3A CRC64;
MATASNSVEI DPVFIKALKL LHSKHPDSLD QLRTLRDEFV RQHSQQAPTS SKEKPKEVKL
GLHTERRPSA IVSTAEVKAK LTEKKQESEP KQSNPSVKAE PTKSFPIEEA NVETLEVGSS
MIETVELSSS SFMDQSSSKK AKLQFDVEDV LDEGDLESPT ALQPVVDDLM IDWGSVCSIC
CRDESKILGN QLVECHECHS LYHQRCHEPR VMDSEVNDPR HVWYCAQCVR RMREMASSAS
PKSRQTESAT FSKPQTSSHR PIPLAPFKRP SINDTKPVSS PTMHQSFAIP ALSTASSSSA
GASKLSVSSG ATSSQNVAAM QHSALKRLQM VKKKAQQRVL NHQQIRIPRR
//
