ID A0A2B4S7R4_STYPI Unreviewed; 685 AA.
AC A0A2B4S7R4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=peptidylprolyl isomerase {ECO:0000256|ARBA:ARBA00013194};
DE EC=5.2.1.8 {ECO:0000256|ARBA:ARBA00013194};
GN Name=Nktr {ECO:0000313|EMBL:PFX24562.1};
GN ORFNames=AWC38_SpisGene10823 {ECO:0000313|EMBL:PFX24562.1};
OS Stylophora pistillata (Smooth cauliflower coral).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC Astrocoeniina; Pocilloporidae; Stylophora.
OX NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX24562.1, ECO:0000313|Proteomes:UP000225706};
RN [1] {ECO:0000313|Proteomes:UP000225706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA Tambutte S., Allemand D., Aranda M.;
RT "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT digitifera provides evidence for extensive differences between species of
RT corals.";
RL bioRxiv 0:0-0(2017).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[protein]-peptidylproline (omega=180) = [protein]-
CC peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA-
CC COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833,
CC ChEBI:CHEBI:83834; EC=5.2.1.8;
CC Evidence={ECO:0000256|ARBA:ARBA00000971};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFX24562.1}.
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DR EMBL; LSMT01000173; PFX24562.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2B4S7R4; -.
DR STRING; 50429.A0A2B4S7R4; -.
DR EnsemblMetazoa; XM_022936594.1; XP_022792329.1; LOC111331472.
DR OrthoDB; 2919818at2759; -.
DR Proteomes; UP000225706; Unassembled WGS sequence.
DR GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006457; P:protein folding; IEA:InterPro.
DR CDD; cd01926; cyclophilin_ABH_like; 1.
DR Gene3D; 2.40.100.10; Cyclophilin-like; 1.
DR InterPro; IPR029000; Cyclophilin-like_dom_sf.
DR InterPro; IPR020892; Cyclophilin-type_PPIase_CS.
DR InterPro; IPR002130; Cyclophilin-type_PPIase_dom.
DR PANTHER; PTHR11071; PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; 1.
DR PANTHER; PTHR11071:SF561; PEPTIDYL-PROLYL CIS-TRANS ISOMERASE H; 1.
DR Pfam; PF00160; Pro_isomerase; 1.
DR PRINTS; PR00153; CSAPPISMRASE.
DR SUPFAM; SSF50891; Cyclophilin-like; 1.
DR PROSITE; PS00170; CSA_PPIASE_1; 1.
DR PROSITE; PS50072; CSA_PPIASE_2; 1.
PE 4: Predicted;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000225706};
KW Rotamase {ECO:0000256|ARBA:ARBA00023110}.
FT DOMAIN 14..179
FT /note="PPIase cyclophilin-type"
FT /evidence="ECO:0000259|PROSITE:PS50072"
FT REGION 186..685
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..255
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 256..270
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 300..325
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 349..373
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 399..436
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 437..466
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 477..515
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..549
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 557..597
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 605..643
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 660..679
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 685 AA; 78212 MW; 31066D1E356D2F86 CRC64;
MAVPKAKGYR PRCFFDVEIN GSLVGRVIFE LFADICPKTC DNFRALCTGE NGLSKVSGKT
LHYKGSPFHR VIKNFMVQGG DFTKGNGTGG ESIYGGMFDD ESFEAKHDRA MLLSMANRGP
NTNGSQFFIT TQPTPHLDGI HVVFGHVLQG HEVVSEIENQ KVDDKSRPQV DVKIANCGEL
IPKAKAKAMA KKAEKKKKKR KESSTASESS SESDTDSEGE SSSDEKRKKK RSKKKKKEKR
KDSAKKKGKK NKAKDKKMKE MKDGSDNEKS QKSPEPFSTV AADEIPDVPN NSFLFRRSRT
PSPVREKRIA EGKDRRSKSP TTEKTSLRKS RVSQSGRILR GRGNMRYRTP PPSNESNSSV
TRITPPWNRS LQRRSRSPPR RARSPRGRSR SPRDSSRSPR RRVSHRSNSP RSSRRRFKSP
QRRSNSPRRS PKSPRRRSRS PQRELEKESQ AKQESSLKEI SKQTDHSSPD HTNPSNLTRT
YRERDSGKRY DSEDSEPVTP HKNSFKKREI EEHGTTSPVT DSYKQVRNQK KRGLKSSSSS
DSDEQQGNGN DGVLYLKRKR ANLELRSHSN STGRHSRSET RDYVEDSKTK QSLNEEGRIG
HTDGPNVSIK HDEGKREYGE SNRDSVPQNR QQYKEDKHTN SDSSYSSDSD SDDSSERNRK
SRHRHHRHRH HHHRHRHDRE RNSSL
//
