ID A0A2B4S964_STYPI Unreviewed; 1831 AA.
AC A0A2B4S964;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Poly [ADP-ribose] polymerase {ECO:0000256|RuleBase:RU362114};
DE Short=PARP {ECO:0000256|RuleBase:RU362114};
DE EC=2.4.2.- {ECO:0000256|RuleBase:RU362114};
GN Name=Parp14 {ECO:0000313|EMBL:PFX25340.1};
GN ORFNames=AWC38_SpisGene10017 {ECO:0000313|EMBL:PFX25340.1};
OS Stylophora pistillata (Smooth cauliflower coral).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC Astrocoeniina; Pocilloporidae; Stylophora.
OX NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX25340.1, ECO:0000313|Proteomes:UP000225706};
RN [1] {ECO:0000313|Proteomes:UP000225706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA Tambutte S., Allemand D., Aranda M.;
RT "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT digitifera provides evidence for extensive differences between species of
RT corals.";
RL bioRxiv 0:0-0(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFX25340.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LSMT01000153; PFX25340.1; -; Genomic_DNA.
DR STRING; 50429.A0A2B4S964; -.
DR EnsemblMetazoa; XM_022935371.1; XP_022791106.1; LOC111330508.
DR Proteomes; UP000225706; Unassembled WGS sequence.
DR GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd02907; Macro_Af1521_BAL-like; 1.
DR CDD; cd12547; RRM1_2_PAR10; 2.
DR CDD; cd01439; TCCD_inducible_PARP_like; 1.
DR Gene3D; 3.30.70.330; -; 4.
DR Gene3D; 3.30.720.50; -; 1.
DR Gene3D; 3.90.228.10; -; 1.
DR Gene3D; 3.40.220.10; Leucine Aminopeptidase, subunit E, domain 1; 3.
DR InterPro; IPR002589; Macro_dom.
DR InterPro; IPR043472; Macro_dom-like.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR034464; PAR10_RRM1_2.
DR InterPro; IPR012317; Poly(ADP-ribose)pol_cat_dom.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR037197; WWE_dom_sf.
DR PANTHER; PTHR14453; PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR14453:SF67; POLY [ADP-RIBOSE] POLYMERASE; 1.
DR Pfam; PF01661; Macro; 2.
DR Pfam; PF00644; PARP; 1.
DR SMART; SM00506; A1pp; 2.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF56399; ADP-ribosylation; 1.
DR SUPFAM; SSF52949; Macro domain-like; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR SUPFAM; SSF117839; WWE domain; 1.
DR PROSITE; PS51154; MACRO; 2.
DR PROSITE; PS51059; PARP_CATALYTIC; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000256|RuleBase:RU362114};
KW NAD {ECO:0000256|RuleBase:RU362114};
KW Reference proteome {ECO:0000313|Proteomes:UP000225706};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176};
KW Transferase {ECO:0000256|RuleBase:RU362114}.
FT DOMAIN 140..216
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 944..1133
FT /note="Macro"
FT /evidence="ECO:0000259|PROSITE:PS51154"
FT DOMAIN 1166..1408
FT /note="Macro"
FT /evidence="ECO:0000259|PROSITE:PS51154"
FT DOMAIN 1636..1831
FT /note="PARP catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51059"
FT REGION 74..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1140..1165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..117
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 118..135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1150..1165
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1831 AA; 205094 MW; DCA640BE277D6689 CRC64;
MNSSRILVSG FPDGTSQTAL MIYFQSVRES GGGDVESIDI DRRTDQITFE EAQVADRVLS
RSHTFKNCTL QVTRMPMHQV KPSRLEENRR TSLDEQFKNQ DTRQNNRRQR DDASEEPPSP
QESASAASAQ NGSPIPKLQY TIEVTGLPED ASEDLVTNYF ENTRRSKGGA VSSVVMTPEL
RKCLVTFESP DDAERTINYS SHVLSGASIQ VSLFEEEEES AVNSGENGED EEEEDGITII
VSGIMPSTSE DAVIFYFENS RRSGGGDVSE IHFNEKGEAI ITFSEVKVVR QPPPKKVPLD
PLRVHVQGIS ETTTIDCLSF YLEKFAGVEV EKVYLGEKNN ALAVFESETD FESLLHKVNK
DKKGLEGKKP RLERVAVCSC ILVTGLKKES TDHTIELYFD NEKRSGGKDV CRVERIRKDQ
ALVFFEDHTY IQVSVQDVIV RSQRQAHKID GVELEVTPYY PFLKNAASKT TEMKFDPDTY
QYIRVHHKIE LQTSLEKYSV EAELSDGSIL IISPTETKCD PSWEEGAESC KNFLLSFKKS
EVPVPSEIYD EVSKRWQGQT PSQGTANFLL SFDNHRRQAV ILGKEALVEK EEEKLKKLIT
DVKENSELMK TVVEVVETNY TKSRLTLLEM SGLCNKLSDK HRHLSINIDS TGEKLCFKGP
RKNIQEVKLE VVTFISKVIE RTTEQPTGII DVLRQQHVSK FIQELFEKKS IQAVILLDQG
RSSNEVQVVG VNEKNAKEAK VILEDSLKEK SIHLKPENAQ VINGREWKDF KSSLTSELKV
GIAVDASVSN VWISGILEDV EQCSDQMQKF LEMKTIFHKV IQVEEGTGRF ISTFWKKKLE
AVKGELSNCY VDMRVTSDYM GIEVSGTTEG MAKCIPEIHD LIDAVQKECM TVNKPGMKKF
FEDVKGKSIL KSVEDASKCV ILTSENNEVQ NVPDFTREEH MAAEFFCSFS TKHGKTISVM
KGDITKDPVD AIVNAANERL QHIGGVAYAI VKEGGREIKD ECDTFIKQNG PLLDGHVFVS
TAGSLPCNQV IHAVGPRWDK GKRREVEVTQ EERYLKQAII NVLAEAKHLT SLAIAGVSCG
IFDFPRDLFA KIILDTVLAF WEKDSNCRLS EIHLIDKDDQ TVKAFEGELR RFSDQQTFHP
RKVGKSDFGS EESHSGNART GQVRTARAPR SFVTQGIRVT VKSGYLADEQ ADILVGTAAS
NLSLSQNPCA RALSQRAGPA LQRECDNRGH VAVGDIAVVD QPGNLKCQAV FFAVCSEWES
GKGKKVLKKI IRKCLEEATR AGMASIAFPA IGTGILAFPR TEVAEIYFDE AQPGDITDER
TDAIAIISNP DLDLKRGGGA GAAILRKGGA SIQRECNLGV TAKSCAETML SALCDFNNHQ
PASLQLVKMT IFQKEMTKDV RQAMEEASGQ APADKPGIIQ RVVSTFSCLL GFGEKDNEFT
KSFQEDSNKI LHLAIFAGCM EDIQRATRRI NEIMTENSTT KTIEHEAVSM LFKDNLRKIH
TLEQIHDVSV SVEKLVGRIV IRGQPSDLLN VTGEIHTILH KVKEEEHERK RAEALLNDIR
WKCHDGANFV EFGSLINAKI EAAYHEKKTR ITITTEENED FRIDFGSMTM TDPLGVATPV
QRIDLRKGVL LPTYWIPQPK DSQGLEITVH LVELDPAKDT QQYETVQDRF KQTCPNQIVK
IERVQNPALF GSYIIRKQKM DETKGSNEQW LFHGTPGDNC KLINHTGFNR SFHGKNATMY
GNGVYFAEDA SYSARSTYSP SDPSGQRYMY YSRVLVGEYT QGNQGLLTPP AKNPNDPTDT
FDSVVDQIPN PKIFVVFYDW QCYPEYLITF R
//
