ID A0A2B4SE30_STYPI Unreviewed; 1806 AA.
AC A0A2B4SE30;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=Nephrocystin-3 {ECO:0000256|ARBA:ARBA00040387};
GN Name=nphp3 {ECO:0000313|EMBL:PFX26695.1};
GN ORFNames=AWC38_SpisGene8634 {ECO:0000313|EMBL:PFX26695.1};
OS Stylophora pistillata (Smooth cauliflower coral).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC Astrocoeniina; Pocilloporidae; Stylophora.
OX NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX26695.1, ECO:0000313|Proteomes:UP000225706};
RN [1] {ECO:0000313|Proteomes:UP000225706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA Tambutte S., Allemand D., Aranda M.;
RT "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT digitifera provides evidence for extensive differences between species of
RT corals.";
RL bioRxiv 0:0-0(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFX26695.1}.
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DR EMBL; LSMT01000120; PFX26695.1; -; Genomic_DNA.
DR Proteomes; UP000225706; Unassembled WGS sequence.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 8.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45641:SF1; NEPHROCYSTIN-3; 1.
DR PANTHER; PTHR45641; TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870); 1.
DR Pfam; PF13401; AAA_22; 1.
DR Pfam; PF13374; TPR_10; 1.
DR Pfam; PF13424; TPR_12; 8.
DR Pfam; PF13181; TPR_8; 2.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00028; TPR; 21.
DR SUPFAM; SSF81901; HCP-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 6.
DR PROSITE; PS50005; TPR; 12.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000225706};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}; Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}.
FT DOMAIN 351..497
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REPEAT 765..798
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 807..840
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 933..966
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1044..1077
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1086..1119
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1357..1390
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1441..1474
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1483..1516
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1525..1558
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1609..1642
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1651..1684
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1685..1718
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT COILED 250..295
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1806 AA; 204285 MW; BA41D99D2BB6F0F3 CRC64;
MALQPLTNEQ LNYLKFTFVV LNEFPKALRQ AFKQMWNNTF VSLPGFQPWD DSNAVRNLFL
STEGGVTKVP THISYEEWDC TALIQATIYA RSFALPDSKG HHRVLHDLYL KPCKLPRGTF
HSSVVSPTGD KAETFALAID QLRMLRNSLC HLNKSELDKK TFDQYIQLAK DATKALGVSI
GPIDAVGSLT ESDFPTEKVR KLEDDFRTEL QKGNEFLREV KDDLQLLQQS HQEGAEDLRK
TIKSENAATH EKIEIKLAEF QAQNRIVRED VKDELHNLQQ SLKQDTENLK EAIAASQGRI
VAELRQDVKE YLIKEQIPGF RPYTSRLNLP PNFIGRGKEC EEIIGHVTSD STRFVSVWGS
PGFGKTSTAI VVGHQLQNRG LPVYFISLRG LKSKGDLTSK LLSHFRTGDS ENQNLTPADE
IGFIFQRLSD PCVLILDNAD DLLECGEPNV KEETVNLLKD ILNRSEKVKL LLTTRESLAY
LDMSLHGHKS IRIGELDNSS SKELVEKLQE KGKHLCYSGI YQLVVGKTED GVRSLREAIS
LLNKTAEHKL LRLMIFQILA IFYRCAKSDY EMSTTFYDRA VQECREAGDM HLLVIPDNDG
EPNYGNEDRV PSSTENLGNE PVQVAVTYLL SKAIAKTSSA EIIEFSIKLL FGMLQGIEST
NEMTKPGWFK FEENTISMLR NSHNYQEGLS LTQKLITYHL SSLQKRTTDE ENVSSSLHKE
ALAKWYSLRG RNQHCLRLFS EAVSSKQQAL TIILELFGEE DRKTADAHCE LGLSKYALRD
YNAAAESYKR ALDIEIQLLG EEHQETANSY NQLGVTQYAL GDYTSAAESH KRALNIRQKV
LGEEHEVTAD SYSSLGITQC TLGDHRSAVE SHKRVLNIRQ KVLGEEHEKT ANSYHNLAVT
QNALKDYTSA AESLKRALNI RQKVLGEEHE ETADSYSSLG LAQYALKDHN SAAESHKRAL
NIRQKEGLSL TQKLITYHLS SLQKEITDEE NVRSSLHKEA LAKSYLLRGQ NQHCLRLFSE
AVSSKQHALN IILELFGEED RKTAHAHCEL GFSKHALRDY NAAAESYKRA LDIDIQLLGE
EHQDTANSYN QLGVTQYSLG DYTSAAESHK RALNIRKKVL GEEHEKTANT YHDLAVTQYA
LKDYTSAAES HKRALNIRQR VLGEDHEKTA ESYNELGTTQ YALDDYTSAA DYILLGVTQY
ALKDYTSAAE SHKRALNIRQ KVLGEEHEET ASSYHYLGVT QYALKDHTSA AESHKRALNI
RQRVLGEEHE ETVDSYNELR ATQYAIDDYT SSTESEKRAL NIRQKVLGEE HEETANSYRN
LAVIQYALKD YTSAAESHKR ALNIRQRVLG EEHEKTADSY NELGATQYEL KDYTSAAESH
KRALNIRQRV LAEEHETTAD SYNALGATQY ALEDYTSAAE SEKRALNIRQ KVLGEEHEDT
ADTYHYLGFT RYALKDYTSA ADSLKRALNI REKVLGEEHE ETADSYHNRG VTQYALGDYT
SAAESHKRAL NIRKRVLGEE HEKTADSYNK LGATQYALDD YTSATESHKR ALNIRQKVLG
EEHEETANSY CNLWAIQVAL KEYTSAAESQ ERALNIRQKV LGEEHETTAN SYHNLGVTQY
ALKDYTSAAD SLKRALNIRQ KVLGEEHDMT ANSHHNMGVT QYALGDYTSA AESHKRALNI
RQRTADSYHN LGVTQYALKD YTSAAESHKR ALNIRQKVLG EEHEKTADSY HNLGVTQYVL
GDHCSAVESH KRALNIRQKV LGEEHERTAD SYYSLGLPNM HLKITPQPLS HTIEHLTSEE
IYWVKK
//
