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Database: UniProt
Entry: A0A2B4SK07_STYPI
LinkDB: A0A2B4SK07_STYPI
Original site: A0A2B4SK07_STYPI 
ID   A0A2B4SK07_STYPI        Unreviewed;       477 AA.
AC   A0A2B4SK07;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   31-JUL-2019, entry version 8.
DE   SubName: Full=Gamma-aminobutyric acid receptor subunit beta-4 {ECO:0000313|EMBL:PFX28867.1};
GN   Name=GABRB4 {ECO:0000313|EMBL:PFX28867.1};
GN   ORFNames=AWC38_SpisGene6365 {ECO:0000313|EMBL:PFX28867.1};
OS   Stylophora pistillata (Smooth cauliflower coral).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC   Astrocoeniina; Pocilloporidae; Stylophora.
OX   NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX28867.1, ECO:0000313|Proteomes:UP000225706};
RN   [1] {ECO:0000313|Proteomes:UP000225706}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D.,
RA   Flot J.-F., Tambutte S., Allemand D., Aranda M.;
RT   "Comparative analysis of the genomes of Stylophora pistillata and
RT   Acropora digitifera provides evidence for extensive differences
RT   between species of corals.";
RL   bioRxivorg 0:0-0(2017).
CC   -!- SIMILARITY: Belongs to the ligand-gated ion channel (TC 1.A.9)
CC       family. {ECO:0000256|SAAS:SAAS00978283}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:PFX28867.1}.
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DR   EMBL; LSMT01000075; PFX28867.1; -; Genomic_DNA.
DR   Proteomes; UP000225706; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   Gene3D; 2.70.170.10; -; 1.
DR   InterPro; IPR006028; GABAA/Glycine_rcpt.
DR   InterPro; IPR006202; Neur_chan_lig-bd.
DR   InterPro; IPR036734; Neur_chan_lig-bd_sf.
DR   InterPro; IPR006201; Neur_channel.
DR   InterPro; IPR036719; Neuro-gated_channel_TM_sf.
DR   InterPro; IPR006029; Neurotrans-gated_channel_TM.
DR   PANTHER; PTHR18945; PTHR18945; 1.
DR   Pfam; PF02931; Neur_chan_LBD; 1.
DR   Pfam; PF02932; Neur_chan_memb; 1.
DR   PRINTS; PR00253; GABAARECEPTR.
DR   PRINTS; PR00252; NRIONCHANNEL.
DR   SUPFAM; SSF63712; SSF63712; 1.
DR   SUPFAM; SSF90112; SSF90112; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|SAAS:SAAS00457684};
KW   Complete proteome {ECO:0000313|Proteomes:UP000225706};
KW   Ion channel {ECO:0000256|SAAS:SAAS00081334};
KW   Ion transport {ECO:0000256|SAAS:SAAS00457623};
KW   Membrane {ECO:0000256|SAAS:SAAS00978300, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|EMBL:PFX28867.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000225706};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00978734,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00978768,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00457659}.
FT   SIGNAL        1     28       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        29    477       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5012744510.
FT   TRANSMEM    257    276       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    319    341       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    458    476       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       57    253       Neur_chan_LBD. {ECO:0000259|Pfam:
FT                                PF02931}.
FT   DOMAIN      262    353       Neur_chan_memb. {ECO:0000259|Pfam:
FT                                PF02932}.
FT   REGION      385    423       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    400    423       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
SQ   SEQUENCE   477 AA;  55183 MW;  471CC7BC3C491CAD CRC64;
     MMFKFYIRAF GVLLRSFMVL ANICPVNATK TDDSKRAVEV DIADGSLPPL TEPPNATAIL
     DKMFVNYDKR LRPMYGGDPV YIYVSLGFLS ISHVTEENME FKGDIYMRQF WKDPRLAYGD
     KNWTLILQGD ILRKMWFPDT YIENGKKTTI HDDTRTVIVF GDGNVFYSVR VTVNAMGLMD
     FKNYPMDVQL FFFRVLSYGF DITQIRYKWI GASLYSTDMA EFYVMNQTLA SDKVKYMIGW
     FDYLDVNFHV RRRIGHYVIR IFFPCILCTV VSWLPFWMDR NEIGDRGALG ITTLLTEVFL
     LQYTNDSMPR VSYVKAADLF LIVSFAFTFM ALLESVIVYN YKKKSFMAES TQTKSLTGGR
     TFFRKRTAKV EEVCKAGTVH INGSYINPTV PAEPEDPPRP LPEPQGKKAP WKEPEDEKQE
     LPRCSALSKS KIRSYYTSVK SYLAKTDLSF FIEMSSRILF PLMYIGFIAF FFGKYGI
//
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