ID A0A2B4SK78_STYPI Unreviewed; 224 AA.
AC A0A2B4SK78;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=DNA replication complex GINS protein SLD5 {ECO:0000256|ARBA:ARBA00014804, ECO:0000256|PIRNR:PIRNR007764};
GN Name=Gins4 {ECO:0000313|EMBL:PFX29776.1};
GN ORFNames=AWC38_SpisGene5441 {ECO:0000313|EMBL:PFX29776.1};
OS Stylophora pistillata (Smooth cauliflower coral).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC Astrocoeniina; Pocilloporidae; Stylophora.
OX NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX29776.1, ECO:0000313|Proteomes:UP000225706};
RN [1] {ECO:0000313|Proteomes:UP000225706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA Tambutte S., Allemand D., Aranda M.;
RT "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT digitifera provides evidence for extensive differences between species of
RT corals.";
RL bioRxiv 0:0-0(2017).
CC -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC DNA replication. {ECO:0000256|PIRNR:PIRNR007764}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR007764}.
CC -!- SIMILARITY: Belongs to the GINS4/SLD5 family.
CC {ECO:0000256|ARBA:ARBA00008187, ECO:0000256|PIRNR:PIRNR007764}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFX29776.1}.
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DR EMBL; LSMT01000060; PFX29776.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2B4SK78; -.
DR STRING; 50429.A0A2B4SK78; -.
DR EnsemblMetazoa; XM_022927954.1; XP_022783689.1; LOC111324409.
DR OrthoDB; 1200818at2759; -.
DR Proteomes; UP000225706; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR CDD; cd11711; GINS_A_Sld5; 1.
DR CDD; cd21692; GINS_B_Sld5; 1.
DR Gene3D; 1.20.58.1030; -; 1.
DR Gene3D; 3.40.5.60; -; 1.
DR InterPro; IPR021151; GINS_A.
DR InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR InterPro; IPR008591; GINS_Sld5.
DR InterPro; IPR031633; SLD5_C.
DR InterPro; IPR038749; Sld5_GINS_A.
DR PANTHER; PTHR21206:SF0; DNA REPLICATION COMPLEX GINS PROTEIN SLD5; 1.
DR PANTHER; PTHR21206; SLD5 PROTEIN; 1.
DR Pfam; PF05916; Sld5; 1.
DR Pfam; PF16922; SLD5_C; 1.
DR PIRSF; PIRSF007764; Sld5; 1.
DR SUPFAM; SSF158573; GINS helical bundle-like; 1.
DR SUPFAM; SSF160059; PriA/YqbF domain; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|PIRNR:PIRNR007764};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR007764};
KW Reference proteome {ECO:0000313|Proteomes:UP000225706}.
FT DOMAIN 48..133
FT /note="GINS subunit"
FT /evidence="ECO:0000259|Pfam:PF05916"
FT DOMAIN 171..224
FT /note="DNA replication complex GINS protein SLD5 C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF16922"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 224 AA; 25661 MW; F0C23BE27FB8A14B CRC64;
MDHREEPDFS LSGETGGGGE SEEEIEVTAA EVLVQLENAW MNEKFAPELL ESKADLVECM
LDQIKEMEGN LKKIKQGDVV ASLHKLEIDR IRFVLSSYIR TRLEKIEKHV VHVLEQEAAR
EEDEPSRLSP EELQYAKAYA DNMESLFKSL ALQHMPANMQ NIDRKKAVPW PNMDKYVFLK
VLENQDQIMI DPDEEPIDLE DRAQYIMRYS AVAPLLTNGS VSLL
//
