ID A0A2B4SLF5_STYPI Unreviewed; 937 AA.
AC A0A2B4SLF5;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 22-FEB-2023, entry version 18.
DE RecName: Full=Exportin-T {ECO:0000256|ARBA:ARBA00018928, ECO:0000256|RuleBase:RU366037};
DE AltName: Full=Exportin(tRNA) {ECO:0000256|ARBA:ARBA00029784, ECO:0000256|RuleBase:RU366037};
DE AltName: Full=tRNA exportin {ECO:0000256|ARBA:ARBA00032199, ECO:0000256|RuleBase:RU366037};
GN Name=XPOT {ECO:0000313|EMBL:PFX29322.1};
GN ORFNames=AWC38_SpisGene5902 {ECO:0000313|EMBL:PFX29322.1};
OS Stylophora pistillata (Smooth cauliflower coral).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC Astrocoeniina; Pocilloporidae; Stylophora.
OX NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX29322.1, ECO:0000313|Proteomes:UP000225706};
RN [1] {ECO:0000313|Proteomes:UP000225706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA Tambutte S., Allemand D., Aranda M.;
RT "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT digitifera provides evidence for extensive differences between species of
RT corals.";
RL bioRxiv 0:0-0(2017).
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex.
CC {ECO:0000256|RuleBase:RU366037}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|RuleBase:RU366037}. Nucleus
CC {ECO:0000256|RuleBase:RU366037}. Note=Shuttles between the nucleus and
CC the cytoplasm. {ECO:0000256|RuleBase:RU366037}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|RuleBase:RU366037}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFX29322.1}.
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DR EMBL; LSMT01000067; PFX29322.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2B4SLF5; -.
DR STRING; 50429.A0A2B4SLF5; -.
DR Proteomes; UP000225706; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0071528; P:tRNA re-export from nucleus; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR045546; Exportin-T_C.
DR InterPro; IPR040017; XPOT.
DR PANTHER; PTHR15952:SF11; EXPORTIN-T; 1.
DR PANTHER; PTHR15952; EXPORTIN-T/LOS1; 1.
DR Pfam; PF19282; Exportin-T; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|RuleBase:RU366037};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU366037};
KW Reference proteome {ECO:0000313|Proteomes:UP000225706};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU366037};
KW Transport {ECO:0000256|RuleBase:RU366037};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555,
KW ECO:0000256|RuleBase:RU366037}.
FT DOMAIN 99..247
FT /note="Exportin-1/Importin-beta-like"
FT /evidence="ECO:0000259|Pfam:PF08389"
FT DOMAIN 319..934
FT /note="Exportin-T C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19282"
SQ SEQUENCE 937 AA; 106106 MW; 4F03372326F26F7A CRC64;
MAENLLQGLQ SAANSTSQAG TLQYFEQLKN SEDGWKLCGD ALVRNLYSDE TVKFFCFQVL
EHQIKTSHAA ASPLNQCTAR NILLTWLRNQ CCSKTDDKNF LKNKAAQVFS LIFVRDYPEG
WPTFFSDLLQ CLQFGAQAVD MYLRILKAID EEVVDRDVIR NQQDAERNMK IKDTIRDTCI
TDLVDSWYHI LNTYENSLSS LTCLCLDVIG AYIEWIDIGL IANDRFISAL LRYMSVEVLR
ESACDCIHEV IMKGMEPVAK RELVESLVSV LEKSGILQLQ EDEDADFLAK VSKLMNAVGT
QLLNSYSKLT KSGDTEAAAK CLHAAEEKMQ YLFRFLSHDD DDVSQNVSGF GYAYLTVLKQ
IANPNEQQKA NLRAILHVII NKMKYDESYN FDHEGEDEVM FMEYRKEMKI LFDNIAQLDP
DLVLVSVHNI LNSTFGQLDG AKFMDVEIAV RVLYMVGEAM SMQQLYSDAS KFSALQQMMS
LFFETVVRYD RFFSSQGQHI PTVLIAFLDE RGLRNPNCTV RSRCSYLFSR FIKSHKANML
NYAHDVLKRL QGLLVISAEN GYQQLLSADD QLFLYESAGI LIVASGAVPE KQLMYMKDLL
SPIIEKFDSI VTKLMSETDD ASSLVYAQQL YHLVAYASRA SKAFPNQQAL KASGCAPCFT
EALPIFLRAL HIPIHRDTIH SGVRQYLHRM IVCLGEEVLP FIPVAVSHLL EGCTARDIQE
FIPLINQIIS RFKTQIGPFL REVFMAIVNR IFIVLGKPAD AKDAQAVKEK ETLRRSYFLF
VGAVVTNDVT GVLTSQTPQD LHQVLLTLIQ GGVEFPDPVA QKISFNILRK LVELWGGSNG
LNGFREFIYE SIVPASFMAP MKSNFDMNDA QTILALQEIA LTQKMILQKQ GVEFIEFLQS
KYLPTLQIAP GLIQEYISAL QHADIKTFKN YIKVTCR
//
