ID A0A2B4SLK3_STYPI Unreviewed; 902 AA.
AC A0A2B4SLK3;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Disrupted in renal carcinoma protein 2-like {ECO:0000313|EMBL:PFX29387.1};
GN Name=dirc2 {ECO:0000313|EMBL:PFX29387.1};
GN ORFNames=AWC38_SpisGene5828 {ECO:0000313|EMBL:PFX29387.1};
OS Stylophora pistillata (Smooth cauliflower coral).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC Astrocoeniina; Pocilloporidae; Stylophora.
OX NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX29387.1, ECO:0000313|Proteomes:UP000225706};
RN [1] {ECO:0000313|Proteomes:UP000225706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA Tambutte S., Allemand D., Aranda M.;
RT "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT digitifera provides evidence for extensive differences between species of
RT corals.";
RL bioRxiv 0:0-0(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFX29387.1}.
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DR EMBL; LSMT01000066; PFX29387.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2B4SLK3; -.
DR EnsemblMetazoa; XM_022928664.1; XP_022784399.1; LOC111324986.
DR EnsemblMetazoa; XM_022928665.1; XP_022784400.1; LOC111324986.
DR OrthoDB; 1382276at2759; -.
DR Proteomes; UP000225706; Unassembled WGS sequence.
DR GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR049680; SLC49-like.
DR PANTHER; PTHR10924; MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED; 1.
DR PANTHER; PTHR10924:SF27; SOLUTE CARRIER FAMILY 49 MEMBER 4; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR Pfam; PF07690; MFS_1; 2.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 2.
PE 4: Predicted;
KW Lysosome {ECO:0000256|ARBA:ARBA00023228};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000225706};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 141..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 608..630
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 662..685
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 697..716
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 728..752
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 758..780
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 792..815
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 821..840
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 46..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 852..879
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 852..870
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 902 AA; 101804 MW; 6ACFA773B55B6684 CRC64;
MAPGVRSKEA KLKRLSGQTL RLRKKRWLFT GLRAEKNLNG SVLVSSDRDS KMYPTSSKSE
DRKSFLDPEE TELVEVDLDD PWVRREDYKP KRDAHGQDLQ RCSPERVEES LSSDRVLLTE
DKGLYLSDDS LVEVKSYKRR FYILMLFSMI SFSQYCAWNT YGPIATTAKM VFNWTNTEIA
ILASMDPITY LCTMLLFSWL MDKKGLRRSV LISCAFMLVG TALRCVTSKP SYAIWSMGAG
QLLNGLAGPV AQAAPTLLSS TWFPPEQRTS STAVAALCGS LGVAISFVIG PLVVTDVKYE
LERLIPDRGN VSKNLSDTLD LYMDENTLYS ESIYRDAMYY WPLDNLNISV QNVQSLRRER
KENSSNLRNS GEYWGVQINK GLREFKTNKE GFLFNECITE QGVVHQSLMT DGKSAWVNLG
SFINTCVSDP SLCPDGFTVA LWMKYEVLNR NGLQYFMGTS GNRDGLRGFL IYQDFPYDRE
DHLAIKVENG TVLWKRSFSV PRSNWTHVTF TWDEREGLVI YSNGSNVGGD PKGKTTQLES
DYFTMFTLGR PNNDLTFSKA AYDELAVWER KLHPREIEAI YQRTVGIGIT PDLEEAKQRL
IKDGKKEIMM LLYVECGVVL FLSLLVCMYF PDKPPLPPSK SARRKREDFF AGAKQIFKNK
QFWTLALIYG VTTGVYSGWG ASLAVNLETF SIGQHEAGWI GFYATLAGIG AGLILARCAD
LFGGKMKLLL LVLFFGASGC FLWFSLLCLR MIAYDDAALY KSSILGGFFI SGTIPLFYEL
TVESTYPVAE GVTTGALTLI NNTFTVIFLL VLMVPKVGTE WMNWCMFGAC AGCIPILLGF
HENYRRLDID NDKKTSKEPK KKKEADKSLK RPTSPFGSII SFKHHNVDEL VKKLENTRES
NI
//
