ID A0A2B4SU44_STYPI Unreviewed; 1732 AA.
AC A0A2B4SU44;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=SH3 and multiple ankyrin repeat domains protein 1 {ECO:0000313|EMBL:PFX32072.1};
GN Name=Shank1 {ECO:0000313|EMBL:PFX32072.1};
GN ORFNames=AWC38_SpisGene3082 {ECO:0000313|EMBL:PFX32072.1};
OS Stylophora pistillata (Smooth cauliflower coral).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC Astrocoeniina; Pocilloporidae; Stylophora.
OX NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX32072.1, ECO:0000313|Proteomes:UP000225706};
RN [1] {ECO:0000313|Proteomes:UP000225706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA Tambutte S., Allemand D., Aranda M.;
RT "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT digitifera provides evidence for extensive differences between species of
RT corals.";
RL bioRxiv 0:0-0(2017).
CC -!- SUBCELLULAR LOCATION: Postsynaptic density
CC {ECO:0000256|ARBA:ARBA00034105}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFX32072.1}.
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DR EMBL; LSMT01000027; PFX32072.1; -; Genomic_DNA.
DR STRING; 50429.A0A2B4SU44; -.
DR EnsemblMetazoa; XM_022924088.1; XP_022779823.1; LOC111321257.
DR OrthoDB; 2247290at2759; -.
DR Proteomes; UP000225706; Unassembled WGS sequence.
DR GO; GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.
DR CDD; cd17091; FERM_F0_SHANK; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR24135:SF28; LD13733P; 1.
DR PANTHER; PTHR24135; SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF07653; SH3_2; 1.
DR SMART; SM00248; ANK; 6.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00454; SAM; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 4.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000225706};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT REPEAT 156..189
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 190..222
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 257..289
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 290..322
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 507..566
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 604..697
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1664..1727
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 357..489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 699..728
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 958..1054
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1067..1115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1192..1260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1279..1360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1422..1451
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1500..1583
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1611..1631
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 371..457
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 458..477
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 958..981
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1008..1023
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1030..1050
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1081..1105
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1227..1260
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1281..1312
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1422..1437
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1549..1565
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1732 AA; 190105 MW; 8FA6DD0AB7AC52F4 CRC64;
MKDDVKVESS GGTETAATFE VLVSMPDRKI KKLYHFDVQD KVWNAKLNVI NDLIKNVKDA
VNYGFYDPPC NGKSGKFLEE ERLFTDYPLS GSPPVLEFKY KRRIYRSLVY EQKTLQKVNV
KANQKKFLEL VSSGAVSQVG KMAEKGIDPN FHDDRTGETP LTVAVTKENA REMIVTLVNG
GALLDYRTHD SQTPLHRAAI AGKAISVKTL LDFGASPNYK DLKGLTPLFY TAVYGGDPYC
CETLLNDQAE LHTADHQGKQ EIHLACKNGL VQHLEHLLFY GAQIDARTAS GNTALHVAAL
SNQDECARVL LFRGAKRNIL NYANQSAYEV AAVGGNKEIA ELIKNFSEKD IVKFSGKPNY
STRRRKSVSK PKASSLFSRT PSETQLSVKS DSSPPSPGSS IHSLPSTTAS ETASVDESTV
TMNGDTEIHN GSRMNLNRTL SASSTASDSS YGSESDSGEM SPRDHEKRKK RRWRQYSEPN
IAQKPAVPPV KAVSGAATIR KRLYASVPGR RFVAIKDYRP LMAGELALEK GDEVEVLFVG
EKGYWEGRVG NSTGWFHHSY VEEKKGKGKP RPKTMFARPP PQAKSNFQDL NHVGSNNSAK
APRIVTLHRS SAGFGFQMRG ANSQVPRLNF EPTAEFPALQ YFGELEAGGQ ADLIGIKAGD
FILEVNGEDV RTATHGHVVA LIQKSGELVN LKIVTAKSPA VNGTDHTDGK GYKPPPPPPN
RDPSTTLTLG RMSTLSSSRP SLFEMSMGES FEEPTSYRVD SVITVSKENR WHSLQRQKPQ
ARKPVGVQMK SQTLVKRRSS GDLKGAGKIG YQRAQSVHSM LPPAYESVIG KRPLSAAVPV
DMPVVPDDRR LPRSMLVDNT TLSKHHLTAK STPNLDKPIL DNGLNNGYGP LPMEVRRESM
HGPYNYHTLD RNKTRAVGST KVEAVVATPV KATVAAVQSA EAKPEITVVA TPVEVVESTP
TIQSDTPRAP VKTSSEAQAT RNKAEKPPVP PKPRTLSDAL QEAVAARNQR MSRKSSAPEI
EVPSSVVVTN ARGRRVSTPS KLNPRNMGDA SQKVRSDIMT RLEEKFTEDD GQVETGGSER
FHTLPRQQQK PYRINKESSI PTAVDDQSDS DKKGLVMASS DDILRRYTSP TRDMNRQSSL
DATEAVLRNT KTGNENFQRQ LSEPVGFDRQ PRAQALVKPP AVPLQQIQLG IRGKPAVPPP
PSIAPNKDIP STPVRKGVIT ADALSAKKSK LKSTANENEI SSNAKGASAS TSSTSPNLAT
QHSDLLAKAI AARAARISTQ SHADADLNPV GKTESSSSYV GQTESSSNYV GVQKGPYPKE
LNNNKIKSPM EVRVVNSRGK PSPPVAPKKQ FSSPDLRQRK YNETEFTDRR KASLNVGNHS
PRIGEERSLP FEIPAPVLSE EDKSVMFLDE VIRKEAESEN WSLNSWNSGT GSDSSSEVFV
PPPVWPAEQN KDSENLLKPW YECSSQSEES ILAKTSEPEK VTKTITTKKG FQIKLTIESK
RDDSSKVVRT SSRTDSSDMD VSEPLTPKVE ESARTVSPKE MLSNKAVPQE SDLDEELKTP
VAEKGSGKSR FELPPPPDLF TDKDEPYVLL DSPPLPPPLE FSPTESKTLV FNPNEDTENR
NCASPSAESD DSCKDSVTYS DITSIFGGYS RPMQPFLEKP VLDWDCNDVC GWLDSINMAQ
YKETFRENDI QGIHLPELTK AELRELGVKS LGHRMTLENA IARLSQPLES NC
//
