ID A0A2B4SUH2_STYPI Unreviewed; 1715 AA.
AC A0A2B4SUH2;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Tyrosine-protein kinase BAZ1B {ECO:0000313|EMBL:PFX33541.1};
GN Name=BAZ1B {ECO:0000313|EMBL:PFX33541.1};
GN ORFNames=AWC38_SpisGene1590 {ECO:0000313|EMBL:PFX33541.1};
OS Stylophora pistillata (Smooth cauliflower coral).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC Astrocoeniina; Pocilloporidae; Stylophora.
OX NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX33541.1, ECO:0000313|Proteomes:UP000225706};
RN [1] {ECO:0000313|Proteomes:UP000225706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA Tambutte S., Allemand D., Aranda M.;
RT "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT digitifera provides evidence for extensive differences between species of
RT corals.";
RL bioRxiv 0:0-0(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00475}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFX33541.1}.
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DR EMBL; LSMT01000011; PFX33541.1; -; Genomic_DNA.
DR STRING; 50429.A0A2B4SUH2; -.
DR Proteomes; UP000225706; Unassembled WGS sequence.
DR GO; GO:0090535; C:WICH complex; IEA:InterPro.
DR GO; GO:0140801; F:histone H2AXY142 kinase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd15541; PHD_TIF1_like; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR047174; BAZ1B.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR018501; DDT_dom.
DR InterPro; IPR028942; WHIM1_dom.
DR InterPro; IPR028941; WHIM2_dom.
DR InterPro; IPR013136; WSTF_Acf1_Cbp146.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46802; TYROSINE-PROTEIN KINASE BAZ1B; 1.
DR PANTHER; PTHR46802:SF1; TYROSINE-PROTEIN KINASE BAZ1B; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF00628; PHD; 2.
DR Pfam; PF10537; WAC_Acf1_DNA_bd; 1.
DR Pfam; PF15612; WHIM1; 1.
DR Pfam; PF15613; WSD; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00249; PHD; 2.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS50827; DDT; 1.
DR PROSITE; PS51136; WAC; 1.
DR PROSITE; PS01359; ZF_PHD_1; 2.
DR PROSITE; PS50016; ZF_PHD_2; 2.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Kinase {ECO:0000313|EMBL:PFX33541.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00475}; Reference proteome {ECO:0000313|Proteomes:UP000225706};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000313|EMBL:PFX33541.1};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 22..128
FT /note="WAC"
FT /evidence="ECO:0000259|PROSITE:PS51136"
FT DOMAIN 616..680
FT /note="DDT"
FT /evidence="ECO:0000259|PROSITE:PS50827"
FT DOMAIN 1193..1243
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 1196..1241
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 1282..1329
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 1614..1684
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 228..303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 774..813
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 826..861
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1334..1598
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 237..258
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..291
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 842..861
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1355..1396
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1429..1446
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1463..1482
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1715 AA; 194478 MW; 6BE9E05EE430D9DC CRC64;
MPLLGKKSYK PSPFPNDLKS EEEVFVIRET NEVFRSYDEY INRILSYGFQ VWTCQFTGKT
NLKYEEAVAS EEQALKRLKN FPKYFEKTVL QIVHQSTRTL QMLVQECCKV LEKEFLPSEP
VECLVNGKWI QGKILQVHHG DKSESGTDIT YDFESDDIQY CLKGIPPKEI RHIKKIPSAE
LLKCFIRVNT LNPWKTDNSP WLVKSDIAKK YSIAEKLNDF SLVFGKKTIP SSKTPSKGHE
NTEKQRKKTS DKNKSHGKSQ MKKSGLMQKK LDSFRTSSNS KDITVSPSKV SDMTPKKVMP
TKKDIIDICS RPDKDDEKTP SSQLRGTPVK CRLVLTPIKS PQVTAAKSIT PKISDVSKDI
KDVAVEETAK DVVIMGCKTS KSFFSQPSKK VRSSPKQDKC KKFLDSKGML NKESTKTVNA
SKKVDLSEPT VKGTKLKEKK LADGTKSAKK KAKLDVSVAE GELVIVDNDS DNDFQSSPLK
DKEEIRSLKW NQTTHLLTYF GPLVEHHIAN QKWYCGTASE GGFNAAFRKE KPDQAINALI
RKTAKEVSSP SCLALDLSTP QRNHITEKWH AHTEGLNRKF NSRVNGLLKK CDDNDLIDAK
PLPPCKPVNI PVEITAEMFG DIAMIADFVH TFSNLLAPKE TLHISTDNLS QALISGEEGS
PLLSKILVIF LQILLQDGST KGFELGMKLS EMPLTQHTAS EISRIYLNSK LKMLLAFEED
KQLQEILESL EKKDFHLFNP EEKTKILVTL CHEVLSSTAI DDYIGNQRAE ATELRKQKQA
KQKEKNDKIR EEKKRLRKEK EEMKKKEEEA SKKQLKVDEL NVKETGSDCV TSEPHGCCPE
METSNKMEEK RAKEKSEVSL RAEQDMEDYE VVETLRKRRE DMAAKDIINE KKLKEKEERL
AKEEEEQLNL NVAQCLDSLR LKPLGCDRNH GRYWVFNGVA PGIFVEHGWR NLEDLSRPAG
DASKEEKEVG DNADATIETE YQEEVCQEGN DIEMVEETKV ESKMDACAKD GVQESRSAAV
PYEWSCYSTV EEVEALLSCL SIQGLRESEL KKALKEKLPG ITDGIVKRNS SGKVLKPETV
DEAPYSSIKG ELKDTAERLV NGNLAELEND LEEYLEGVDQ AMSASDLALQ LGKLLPAVLP
RFYRGMFHLD NKGSEEAKRR WLDAVNKATT VSRLHLLLGI LDSLVIWDLS AEHARCKICG
RKDIGKTLIL CDHCNQGYHL HCLRPALSEA PEGDWTCPVC KPNERVSSRA ESKNYKEESG
SDIEDSKDEA SEASLNSCDE NEDYCYTCGE DGDLICCDTC PLVFHTTCHQ PPLRNIPRGA
WSCWFCRQPK DQKRAKGRKS ETSVKAKAKK HLKRMGNFMR ESERRQSSLR IETASKRIRQ
SHSRDGRRRA RDARARAGTR ASVSLEDISD EESIDGRDNQ KHRRVSRRLQ RMYQQDSKDE
LEESSTRGTN VKSFYGKTSR KALKRQVSSE KDDDEFLERR RNAKKKTSAH NKRQILAVFE
DEGDDDGDSE KENLKTSRSA SSQKTTHRST RNRRQVSSSP EESEESGYTE DAAEPNNGRP
LGIKDKNAKN LSASKGGQKA ATKTRRTGES PENSKRRRVN VEMDTCEQIL RALLRHEDSW
PFTQAVNLRE VPDYLDLVST PMDLGTIKEK LNSLEYVDVD SFKADVRLVF SNSDKYNLST
SEVGQAGKNL EQYFDKMFEE NFSSKDKKSK VHRKR
//
