ID A0A2B4SVC3_STYPI Unreviewed; 1738 AA.
AC A0A2B4SVC3;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Collagen alpha-2(IV) chain {ECO:0000313|EMBL:PFX32508.1};
GN ORFNames=AWC38_SpisGene2634 {ECO:0000313|EMBL:PFX32508.1};
OS Stylophora pistillata (Smooth cauliflower coral).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC Astrocoeniina; Pocilloporidae; Stylophora.
OX NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX32508.1, ECO:0000313|Proteomes:UP000225706};
RN [1] {ECO:0000313|Proteomes:UP000225706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA Tambutte S., Allemand D., Aranda M.;
RT "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT digitifera provides evidence for extensive differences between species of
RT corals.";
RL bioRxiv 0:0-0(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
CC Secreted, extracellular space, extracellular matrix, basement membrane
CC {ECO:0000256|ARBA:ARBA00004302}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFX32508.1}.
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DR EMBL; LSMT01000022; PFX32508.1; -; Genomic_DNA.
DR STRING; 50429.A0A2B4SVC3; -.
DR EnsemblMetazoa; XM_022923477.1; XP_022779212.1; LOC111320780.
DR Proteomes; UP000225706; Unassembled WGS sequence.
DR GO; GO:0005604; C:basement membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005201; F:extracellular matrix structural constituent; IEA:InterPro.
DR CDD; cd01450; vWFA_subfamily_ECM; 1.
DR Gene3D; 2.170.240.10; Collagen IV, non-collagenous; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR001442; Collagen_IV_NC.
DR InterPro; IPR036954; Collagen_IV_NC_sf.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24023; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24023:SF533; COLLAGEN ALPHA-6(IV) CHAIN; 1.
DR Pfam; PF01413; C4; 2.
DR Pfam; PF01391; Collagen; 9.
DR Pfam; PF00092; VWA; 1.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00111; C4; 2.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 2.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS51403; NC1_IV; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Basement membrane {ECO:0000256|ARBA:ARBA00022869};
KW Collagen {ECO:0000256|ARBA:ARBA00023119, ECO:0000313|EMBL:PFX32508.1};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Reference proteome {ECO:0000313|Proteomes:UP000225706};
KW Secreted {ECO:0000256|ARBA:ARBA00022530}.
FT DOMAIN 728..908
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 1479..1699
FT /note="Collagen IV NC1"
FT /evidence="ECO:0000259|PROSITE:PS51403"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 83..720
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 911..1474
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 524..540
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 592..606
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 704..720
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1738 AA; 171623 MW; 331DE7E9E1F8144E CRC64;
MSPISVNRPE HNTGPPGKNG LQGPKGYKGE AGVQGPTGTQ GDQGMIGVPG FPGIHGIPGV
PGIAGPKGFM GLCGCDGDKG EPGRTGVDGR VGIAGTPGDQ GSKGLKGDQG PKGDMGPKGP
PGEVGPPGIP GNQGPIGDRG VKGEPGPQGD VGSKADGDVS LLDGEKGDMP GSKGLKGEPG
PLGANGAKGD TGDKPTESGE KGKQGPVGDQ GTVGRQGVPG DNGELGAQGE PGERGPRGEQ
GSKGNPGSAG PIGSTGERGG GLPGRIGNKG MKGTAGRTGD RGGPGKRGDV GPPGSPGASV
FGPKGDVGEP GPTGLPGAPG TAGFPGMRGN AGPPGEEGPV GRNGSLGPPG EDVPGPKGMD
GSRGPKGYSG EQGELGPKGP PAEPLFCPEG DCPDPRVGLK GPPGSPGSQG VRGAQGLPGE
KGANDTCPIC PPGPRGPKGE KGWIGDDGTP GENGTDGNKG AQGTTGDRGP QGPDGSPGPK
GPKGFPGEPG KTGEKGEAPV GPREEVYQPP GPKGDEGSPG FEGSTGPAGN NGSSGPPGSS
GETGLPGEPG MTGLNGSSGK DGQRGAPGIR GTTGQKGEKG IMPMPDIAKN GSKGDPGDKG
SEGDKGAKGE GTSLGELGIR GGPGMDGVQG QKGANGSKGV EGPKGMRGED AQGPAGPPGA
PGQDGSAGGR GEEGAKGDIG MDGPDGAPGK NGSRGMTGEP GGSRDGPKGK DGEDGKKGAK
VCGQENADYA FLMDASRSIL EDEFQLLKDY VKDVIDYLSI GPDLTHVGVI EYSTGAKMEL
PFNQAYDKEE IKRIVDNVTH TKGITRIDLA LKVASKELFD ETIGGMRKSS RKVMVLLTDG
NQTGTDIVPD QVPLVDAIQP LKNLGVKVIA VAIGSVDINQ LRILVTDNDD ILRTESFAKL
RELVRTTVER SCRGPIGDPG LKGPQGFPGE SGGVGLEGLP GMPGKQGPKG DQGRTGTPGP
VGDSGDKGST GDEGPPGFAT PGSKGPKGDP GDPGPPGDPG LSGVNGEQGQ KGLQGEPGFQ
GNKGAIGPDG PPGPPGEAGA AGEPGTSGSQ GITGFNGIDG EMGPPGDPGV SGDPGPPGAK
GEPGLFGEPG LDLQGEKGQP GPKGADGLPG LNGFPGERGD NGSPGRSGNA TPGEQGGTGL
PGIKGQKGDA GPQPGEGVVL PSGNQGDVGA DGKMGMPGLN GGPGQQGRQG ERGGNGPPGV
AGVIGDQGAP GPLGEIGARG MPGIPGESGA QGDPGADGAK GVQGDRGEAG SNGQNGERGA
RGPRGQGGID GISGEPGDVG PPGDPGSRGL NGSKGLPGIT GLDGPPGPPG APGDQGPTGE
QGARGEMGEM GPPGPKGLKG LVGPRGLSGI VGEKGEQGSN GTIGGPGIRG DPGNRGPEGE
RGANTITPGP KGEKGVAGLP GLFGRKGTPG NQGPRGPPGD VQGPKGNPGL PGLPSENKGP
RGEEGVPGKR GGPGFPGDQG LPGQDGPTGN IGKAATGEGY HLVVHSQSPR IPDCPLNLTR
LWTGYSLLYV QGHDTSHGQD LGASGSCMRR FTTMPYLFCN INDQCYYASR NDYSYWLTTD
IQIPMMPISA PAVEPFVSKC AVCEAPGPVV ATHSQSTQNP DCPAGWEAIW NGYSFLMHTG
AGGSGSGQSL SSPGSCLRTF RHNPFFECHG RGTCHYFANK YSFWLSTVGQ MFVAQTPETL
KPGNLLSRVS RCTVCYRVAS KKKKRHRALY PKVLPEQRKL SSASLKLQSA AQQLSRRS
//
