ID A0A2B4SWX2_STYPI Unreviewed; 704 AA.
AC A0A2B4SWX2;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=PC3-like endoprotease variant B {ECO:0000313|EMBL:PFX33370.1};
GN ORFNames=AWC38_SpisGene1693 {ECO:0000313|EMBL:PFX33370.1};
OS Stylophora pistillata (Smooth cauliflower coral).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC Astrocoeniina; Pocilloporidae; Stylophora.
OX NCBI_TaxID=50429 {ECO:0000313|EMBL:PFX33370.1, ECO:0000313|Proteomes:UP000225706};
RN [1] {ECO:0000313|Proteomes:UP000225706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Voolstra C.R., Li Y., Liew Y.J., Baumgarten S., Zoccola D., Flot J.-F.,
RA Tambutte S., Allemand D., Aranda M.;
RT "Comparative analysis of the genomes of Stylophora pistillata and Acropora
RT digitifera provides evidence for extensive differences between species of
RT corals.";
RL bioRxiv 0:0-0(2017).
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240, ECO:0000256|RuleBase:RU003355}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PFX33370.1}.
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DR EMBL; LSMT01000012; PFX33370.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2B4SWX2; -.
DR EnsemblMetazoa; XM_022944685.1; XP_022800420.1; LOC111338242.
DR OrthoDB; 2996461at2759; -.
DR Proteomes; UP000225706; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd04059; Peptidases_S8_Protein_convertases_Kexins_Furin-like; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.30.70.850; Peptidase S8, pro-domain; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR034182; Kexin/furin.
DR InterPro; IPR002884; P_dom.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR032815; S8_pro-domain.
DR InterPro; IPR038466; S8_pro-domain_sf.
DR PANTHER; PTHR42884:SF30; ENDOPROTEASE AEX-5; 1.
DR PANTHER; PTHR42884; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED; 1.
DR Pfam; PF01483; P_proprotein; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR Pfam; PF16470; S8_pro-domain; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF54897; Protease propeptides/inhibitors; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51829; P_HOMO_B; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00136; SUBTILASE_ASP; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000225706};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..704
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013038566"
FT DOMAIN 473..603
FT /note="P/Homo B"
FT /evidence="ECO:0000259|PROSITE:PS51829"
FT REGION 196..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 585..645
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 171
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 216
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 397
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 704 AA; 78570 MW; AFDD7A7BE2071216 CRC64;
MVNVVLFVFL VSLSVVYCES DHGDGEIYTN TWAVELDSHD EELAHNIAEN LGFKNNGPIA
NLPGYFAFVH EKSERRQRRS SHTQLLDHPR VKWAEQQTVL IRQKRGFNTW DEALMLVERA
QRNRRLFNDP LWKNQWYMGT LDFADTRGNL GVLQAWKMGY TGKGIVVTIV DDGLDHTHPD
LSKNYDEAAS LDVNNKTSVG VDHDPTPDDT NLSNDHGTKC AGEVAAEADN NICGVGVAYN
AKIGGIRMLD GTITDQIEAE ALGYNCDYID IFSASWGPKD DGKTFGKPER LGSGAMEKCV
REGRDGKGVL YIWATGNGGA SQDDCSCDGY TSSIYTLSIA SVSANGCKTF YDESCPSTMG
VVFTGDVGSQ CSKRESYSHL VTTSLFHKCV TSFSGTSCAA PLAAGIFALV LEANPDLTWR
DMQHLVVKTA RKNEPDSPSW STNGAGHKYS RSYGFGVLNA EDLINAAKEW EHVDTQQKYT
LRGLLTPDTA TLRSKGEVEL KLVNDKEDIQ KLEHVQFNVS IDHRRRGDLV IDLISPSGTT
SRLLAKRPRD DGTRLAYWPF MTVEFWDEDP QGEWIVKIRD EKSENDYSPR SHGILFDEGE
SRDEPSIAND LSHGRFKEDY MSLSKRSKEK RHEKFPQRSE DQPSFQRELI HGRFKEDYMK
SVKGPNQPIN VASDESSMCS HSKSLQGPIA GCVRNWSLVM YGTA
//
