ID A0A2B7WPA3_9EURO Unreviewed; 656 AA.
AC A0A2B7WPA3;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=glycine--tRNA ligase {ECO:0000256|ARBA:ARBA00012829};
DE EC=6.1.1.14 {ECO:0000256|ARBA:ARBA00012829};
DE AltName: Full=Diadenosine tetraphosphate synthetase {ECO:0000256|ARBA:ARBA00030057};
GN ORFNames=GX51_06811 {ECO:0000313|EMBL:PGG98398.1};
OS Blastomyces parvus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX NCBI_TaxID=2060905 {ECO:0000313|EMBL:PGG98398.1, ECO:0000313|Proteomes:UP000224080};
RN [1] {ECO:0000313|EMBL:PGG98398.1, ECO:0000313|Proteomes:UP000224080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH130 {ECO:0000313|EMBL:PGG98398.1,
RC ECO:0000313|Proteomes:UP000224080};
RA Munoz J.F., Mcewen J.G., Clay O.K., Cuomo C.A.;
RT "Comparative genomics in systemic dimorphic fungi from Ajellomycetaceae.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC {ECO:0000256|ARBA:ARBA00008226}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PGG98398.1}.
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DR EMBL; PDNC01000121; PGG98398.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2B7WPA3; -.
DR STRING; 2060905.A0A2B7WPA3; -.
DR OrthoDB; 546660at2759; -.
DR Proteomes; UP000224080; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004820; F:glycine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006426; P:glycyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00774; GlyRS-like_core; 1.
DR CDD; cd00858; GlyRS_anticodon; 1.
DR Gene3D; 3.30.40.230; -; 1.
DR Gene3D; 3.30.720.200; -; 1.
DR Gene3D; 3.40.50.800; Anticodon-binding domain; 1.
DR InterPro; IPR002314; aa-tRNA-synt_IIb.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004154; Anticodon-bd.
DR InterPro; IPR036621; Anticodon-bd_dom_sf.
DR InterPro; IPR027031; Gly-tRNA_synthase/POLG2.
DR InterPro; IPR033731; GlyRS-like_core.
DR InterPro; IPR002315; tRNA-synt_gly.
DR NCBIfam; TIGR00389; glyS_dimeric; 1.
DR PANTHER; PTHR10745:SF0; GLYCINE--TRNA LIGASE; 1.
DR PANTHER; PTHR10745; GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2; 1.
DR Pfam; PF03129; HGTP_anticodon; 1.
DR Pfam; PF00587; tRNA-synt_2b; 1.
DR PRINTS; PR01043; TRNASYNTHGLY.
DR SUPFAM; SSF52954; Class II aaRS ABD-related; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:PGG98398.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000224080}.
FT DOMAIN 173..523
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
SQ SEQUENCE 656 AA; 74509 MW; B064F353E1D8A1A0 CRC64;
MATSTTKTGQ PLDRPTLDSL LRRRLFYTPS FEIYGGVSGL YDYGPPGCAL QANVVDIWRK
HFVLEEDMLE VDCTMLTPHE VLKTSGHVDK FADWMCKDPK TGEIFRADHL VEEVLESRLK
GDKEARGQKV EVDEEKDAKR KKKAKETKAV KLDDALVTEY EEILAKIDNY DGEELGQLIV
RYDIKNPTTG GDVLPPVSFN LMFQTAIGPS GGVPGYLRPE TAQGQFLTFQ KLLEFNQQSM
PFASASIGKS FRNEISPRSG LLRVREFLMA EIEHFVDPEG GKKHPRFHEV QDMELSFLNR
EVQLSGSTKV ERMTIGKAVA DKIVDNETLG YFLARIQLFL LKVGIDESKI RMRQHMMNEM
AHYAQDCWDA ELFTSYGWIE CVGCADRSAY DLTVHRNKTG APLFVRETRA EPLRIEEWQI
DLDKKKFGPR FKKDGKTVEA AVNALTQDLR EKLSLDLKQN GKIEIDVEGV GSGKVELEKD
IINIEKRTRV ENIREYTPNV IEPSFGIGRI LACLMEHVYW SRPDDEARGV LSFPPIVAPT
KVLLVPLSNH PSFQPLVHRL TVKLRRLGVS NRVDDSSASI GKRYARNDEL GTPFGITVDF
QSLKDNTFTL RERDTTKQVR ASEEEICRAV KSLVDGDETW EDIKKRLPEF VSQDVE
//
