ID A0A2B7X3M2_9EURO Unreviewed; 651 AA.
AC A0A2B7X3M2;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Peroxisomal targeting signal receptor {ECO:0000256|ARBA:ARBA00014710};
DE AltName: Full=Peroxin-5 {ECO:0000256|ARBA:ARBA00032505};
GN ORFNames=GX51_04088 {ECO:0000313|EMBL:PGH03357.1};
OS Blastomyces parvus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX NCBI_TaxID=2060905 {ECO:0000313|EMBL:PGH03357.1, ECO:0000313|Proteomes:UP000224080};
RN [1] {ECO:0000313|EMBL:PGH03357.1, ECO:0000313|Proteomes:UP000224080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH130 {ECO:0000313|EMBL:PGH03357.1,
RC ECO:0000313|Proteomes:UP000224080};
RA Munoz J.F., Mcewen J.G., Clay O.K., Cuomo C.A.;
RT "Comparative genomics in systemic dimorphic fungi from Ajellomycetaceae.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Interacts (via WxxxF/Y and LVxEF motifs) with PEX14; promoting
CC translocation through the PEX13-PEX14 docking complex.
CC {ECO:0000256|ARBA:ARBA00038659}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}. Peroxisome matrix
CC {ECO:0000256|ARBA:ARBA00004253}.
CC -!- SIMILARITY: Belongs to the peroxisomal targeting signal receptor
CC family. {ECO:0000256|ARBA:ARBA00005348}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PGH03357.1}.
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DR EMBL; PDNC01000049; PGH03357.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2B7X3M2; -.
DR STRING; 2060905.A0A2B7X3M2; -.
DR OrthoDB; 2020042at2759; -.
DR Proteomes; UP000224080; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0005782; C:peroxisomal matrix; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR024111; PEX5/PEX5L.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR10130:SF0; GH08708P; 1.
DR PANTHER; PTHR10130; PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5; 1.
DR Pfam; PF00515; TPR_1; 1.
DR Pfam; PF13432; TPR_16; 1.
DR SMART; SM00028; TPR; 4.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 2.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 3: Inferred from homology;
KW Peroxisome {ECO:0000256|ARBA:ARBA00023140};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000224080};
KW Thioester bond {ECO:0000256|ARBA:ARBA00022966};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}; Translocation {ECO:0000256|ARBA:ARBA00023010};
KW Transport {ECO:0000256|ARBA:ARBA00022448};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT REPEAT 361..394
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 514..547
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 651 AA; 72245 MW; 366533D36F04A4B6 CRC64;
MSFLGGPECS TAGNPLTQFT KHVQDDKSLQ RDRLVGRGPG GLQEGMRSRG VMGGQDKMMD
EFLQQGDQMP QGPAQPFAME QMRRELENFQ AAPARTGSPA WAAEFDHGEQ ARMEAAFKPG
MGRAFPGGPE FNAAEFARFR QQNRNGMQGT ATPATSSAPM MNSYQPQMMG FGGMNSGYMG
MMGQPYGMGM QQHHPPQQST QEDKGKGRMV ELDDENWEAQ FAEIAASGQK DEDAEANAAI
EAELNEVDRS VHTETDEFGR FENIWKNIQA ETAARRQLVN EDLDFDNMNL GDFGEWDHFD
STINTHPRDP QMGDYLFEEE NAFKSVNNPF EEGVRIMREG GNLSLAALAF EAAVQKDPKH
IEAWTMLGSA QAQNEKESPA IRALEQALKL DPNNLDALMG LAVSYTNEGY DSTAYRTLER
WLSVKYPQLV DPSTLSGDSD LSFTDRHILH ERVTALFIQA AQLSPQGEQM DPDVQVGLGV
LFYGAEEYSK AVDCFTAALA STESGISNQK DQVHLLWNRL GATLANSGRS EEAIEAYEKA
LTINPNFVRA RYNLGVSCIN IGCYPEAAQH LLGALSMHKV VEEEGRERAR DIVGDGVDEA
QLEHMIHISQ NQSTNLYDTL RRVFSQMGRR DLSDLVVSGM DVSVFRSEFE F
//
