ID A0A2B7XCT4_9EURO Unreviewed; 751 AA.
AC A0A2B7XCT4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Acetoacetate-CoA ligase {ECO:0000313|EMBL:PGH06765.1};
GN ORFNames=GX51_02206 {ECO:0000313|EMBL:PGH06765.1};
OS Blastomyces parvus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX NCBI_TaxID=2060905 {ECO:0000313|EMBL:PGH06765.1, ECO:0000313|Proteomes:UP000224080};
RN [1] {ECO:0000313|EMBL:PGH06765.1, ECO:0000313|Proteomes:UP000224080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH130 {ECO:0000313|EMBL:PGH06765.1,
RC ECO:0000313|Proteomes:UP000224080};
RA Munoz J.F., Mcewen J.G., Clay O.K., Cuomo C.A.;
RT "Comparative genomics in systemic dimorphic fungi from Ajellomycetaceae.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PGH06765.1}.
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DR EMBL; PDNC01000019; PGH06765.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2B7XCT4; -.
DR STRING; 2060905.A0A2B7XCT4; -.
DR OrthoDB; 45466at2759; -.
DR Proteomes; UP000224080; Unassembled WGS sequence.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:PGH06765.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000224080}.
FT DOMAIN 48..105
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 116..437
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 619..671
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 751 AA; 81530 MW; 230C8DA8D6C6E328 CRC64;
MATDNPTSNG DAPAAKPLWQ PSSPENTRIH SFMALVRQKY GLQQLTTYHE LWKWSVSEPA
AFWEEVWHFT GVRAQKPYDK VLDTDAPLFP KPVFFQGCLL NFAENLLFPA SNPDQNSVAV
IAATESTREH ISWKDLRERV RRCALSLRAA GVVRGDRVAG FVGNHANTLV AMLAATSIGA
LWSAVSTDTG VHAVLERLQQ IEPVVLFVDN ASPYNGKVHP THAKVVELTA SLASLRYVVV
FDAVQGYEFD VESVKSPNGR SVTYAEFLNT SSSKDASAPL RFEPLPPDHP VYILYSSGTT
GAPKPIVHGA LGTLIQHKKE HALHGDIGPG DRLFYFTTTT WMMWHWLVSA LASGASIVVY
DGSPFRPLDP EDGKGDMAMP RLIDELHITH FGTSAKYLSV LEQSVLNPTK HPHRPVQLRT
LKAIFSTGSP LAPSTFDYVY SSIHPDIMLG SITGGTDIIS LFGASCPILP VHRGEIQCRG
LGMAVSVFDY AGNDISATDD AGDLVCTVPF PAQPVMFWPP GPVGAEKYRK SYFDLFGPST
WHHGDFVKIN STTGGMEMLG RSDGVLKPAG VRFGSAEIYN VILKHFANEV EDSLCIGRRR
NGIENDETVV LFVKLAGSTS PATTTTTPTT SASTSTSPST SVSASSSTVS IPNNESIQDI
PTTNNNSNNK APPLLMPAAL ASRIQATIRK ELSARHVPAI IDACPEIPVT TNGKKVENAV
KQILCGLNIK TGASVANAKC LEWYRRWAVE N
//
