ID   A0A2B7Y0W4_9EURO        Unreviewed;       818 AA.
AC   A0A2B7Y0W4;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
GN   ORFNames=AJ79_02632 {ECO:0000313|EMBL:PGH15106.1};
OS   Helicocarpus griseus UAMH5409.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Helicocarpus.
OX   NCBI_TaxID=1447875 {ECO:0000313|EMBL:PGH15106.1, ECO:0000313|Proteomes:UP000223968};
RN   [1] {ECO:0000313|EMBL:PGH15106.1, ECO:0000313|Proteomes:UP000223968}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH5409 {ECO:0000313|EMBL:PGH15106.1,
RC   ECO:0000313|Proteomes:UP000223968};
RA   Munoz J.F., Mcewen J.G., Clay O.K., Cuomo C.A.;
RT   "Comparative genomics in systemic dimorphic fungi from Ajellomycetaceae.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PGH15106.1}.
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DR   EMBL; PDNB01000028; PGH15106.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2B7Y0W4; -.
DR   STRING; 1447875.A0A2B7Y0W4; -.
DR   OrthoDB; 1363487at2759; -.
DR   Proteomes; UP000223968; Unassembled WGS sequence.
DR   CDD; cd13311; PH_Slm1; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR046868; BAR_4.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR046869; SLM1/RGC1-like_PH.
DR   InterPro; IPR043453; Slm1_PH.
DR   PANTHER; PTHR31941:SF1; ACTIVATOR OF SKN7 PROTEIN 10-RELATED; 1.
DR   PANTHER; PTHR31941; CYTOSKELETAL SIGNALING PROTEIN SLM1; 1.
DR   Pfam; PF20400; BAR_4; 1.
DR   Pfam; PF20399; PH_20; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
KW   Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000223968};
KW   Transferase {ECO:0000256|ARBA:ARBA00022676}.
FT   DOMAIN          439..544
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          1..143
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          564..585
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          629..668
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          698..798
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..52
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        69..85
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        95..116
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        698..724
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        733..798
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   818 AA;  89645 MW;  6BB94112084E370C CRC64;
     MATRPRTPSH DIHTTTPNTT SESPHRNLVN GSASGDSRPA SYIASSSIAP TDFQVRGRPV
     HTSAPAQPSR LLEEISQSSR RGSSVLDGAT PGELQRSESR ASVALSMLSS RASGTLKKKP
     SLGKKGSLRR SGSRRSSRAG SVRTIALGEK EKYGLVEGDE LNSAFYVPIP TKSDPTEVLA
     ERFHAWRKVL KDLIVVFREV QKSYEIRSKT LLSISNSINN VVIPPVFLAS GGVGDATKIL
     KEHHRQAMIE SAKAREIETE VIRQMSSLRA DLQQKIKEIH RLSGDFKNSV DKEVEGTRRA
     VRHLQEALGL VDTDPAATSG KGDPFLVKCA VQKQLDKQMQ EENYLHNAYL NLEFSGRELE
     RIVVAEIQKS YNLYANILKH NADISYETAG QLTEGPVSLP PDHEWNAFVT QNDSMVDPQL
     PVRDIQYITY PGKDHPAAAE VRAGMLERKS KYLKSYTPGW YVLSPTHLHE YKYADRIEYQ
     TPVMSLYLPE QKLGTHSQAG SSSHKFMLKG RQTGSMHRGH AWVFRAESHD TMLEWYNDIK
     NLTEKTGEAR NAFVRKHVRT LSGGLNRAGS VSSDGAMDED EADETPYTAD HVVPTQTPPA
     VVEAQWQRPQ PGGHFPSDVQ LNRHSHLPYA SPRKSAEYRD SLTPTGAYPE QAKNQPGDLP
     DGTHGDVAGD IERPALVERH DSNYKEWMAP VAATAALAAS QTNPHPLQPQ TNASTVSSEQ
     EFLSPANEGR GGSRPATLNS SQSSADNRTS AAATTVASTI NNVPSSSDKL GDVSPITTPT
     TTAGGSPNTM RTSSEKVRRL PTMISEFKLP GQYPSASC
//