ID   A0A2B7Y437_9EURO        Unreviewed;       694 AA.
AC   A0A2B7Y437;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=Nucleolar complex-associated protein 3 {ECO:0000256|PIRNR:PIRNR028977};
GN   ORFNames=AJ79_02413 {ECO:0000313|EMBL:PGH15437.1};
OS   Helicocarpus griseus UAMH5409.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Helicocarpus.
OX   NCBI_TaxID=1447875 {ECO:0000313|EMBL:PGH15437.1, ECO:0000313|Proteomes:UP000223968};
RN   [1] {ECO:0000313|EMBL:PGH15437.1, ECO:0000313|Proteomes:UP000223968}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH5409 {ECO:0000313|EMBL:PGH15437.1,
RC   ECO:0000313|Proteomes:UP000223968};
RA   Munoz J.F., Mcewen J.G., Clay O.K., Cuomo C.A.;
RT   "Comparative genomics in systemic dimorphic fungi from Ajellomycetaceae.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for synthesis of 60S ribosomal subunits and the
CC       transport of pre-ribosomes from the nucleoplasm to the cytoplasm.
CC       {ECO:0000256|PIRNR:PIRNR028977}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|PIRNR:PIRNR028977}.
CC   -!- SIMILARITY: Belongs to the CBF/MAK21 family.
CC       {ECO:0000256|ARBA:ARBA00007797, ECO:0000256|PIRNR:PIRNR028977}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PGH15437.1}.
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DR   EMBL; PDNB01000025; PGH15437.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2B7Y437; -.
DR   STRING; 1447875.A0A2B7Y437; -.
DR   OrthoDB; 24935at2759; -.
DR   Proteomes; UP000223968; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR005612; CCAAT-binding_factor.
DR   InterPro; IPR011501; Noc3_N.
DR   InterPro; IPR016903; Nucleolar_cplx-assoc_3.
DR   PANTHER; PTHR14428; NUCLEOLAR COMPLEX PROTEIN 3; 1.
DR   PANTHER; PTHR14428:SF5; NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG; 1.
DR   Pfam; PF03914; CBF; 1.
DR   Pfam; PF07540; NOC3p; 1.
DR   PIRSF; PIRSF028977; Nucleolar_complex_p3; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000223968};
KW   Ribosome biogenesis {ECO:0000256|PIRNR:PIRNR028977}.
FT   DOMAIN          124..215
FT                   /note="Nucleolar complex-associated protein 3 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF07540"
FT   DOMAIN          488..683
FT                   /note="CCAAT-binding factor"
FT                   /evidence="ECO:0000259|Pfam:PF03914"
FT   REGION          1..114
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          338..368
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          456..482
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..30
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        36..78
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        79..105
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        339..359
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   694 AA;  77100 MW;  482CCCC9DA6BAF95 CRC64;
     MAPGHAVKRR RLSPSKESNS NGSASNGASV KDFYSRAAEW DLEQDYERRP RKASKKDKEK
     NRLPIKTVEG TIEHVEEPTV VEDESDNPFD TDDDDAEEQD DAAEVEVEAE KPKPHVPAKV
     QILEAKEELA RIAELINEDP EEHTGLFKRL ADMVTDASLS AVKKLALAAQ VAIYRDVIPG
     YRIRPLGESD MAGKVSKEVR RLRNFEQSLL SGYRNLVKLL ASFAKPPKTS KDGDDVEGLK
     AVAIHCACNL LIAVPHFNFR GELMKILVSQ LGRRKVDDNF VKCRETIEQL FSNDEDGIVS
     MEATGLLSKM MKARDYQVHD SVLDTFLHLR LLSEFSSKGS KDSIDKPGED DTIGGKKPKA
     KREFRTKKER KLAKDRKAVA KDMKEADALV SHEQRDKMQA ETLKLVFGTY FRILKLRSPN
     LMGAVLEGLA KYAHLINQDF FGDLLEALKE LIAQADPSTA ETTTTDPSAS GETDTPEETS
     NRNLTREALL CCITAFALLE GQDASKAAST LHLDLSFFTT HLYRSLYPLS TNPDIEYNPN
     KSLHLPDPNI SAPTPAQSSN NNTNKVNFQT PTVLLLRCLQ STLTAKGTSV APPLRVAGFT
     KRLMTASLQL PEKSSLAMLS LLTRVAKQHG RKIAPLWNTE ERRGDGVFDP LAPTVEGSNV
     FAGNVWEGEL LRLHYCPQVR EVAREVEKVV ASVK
//