ID   A0A2B7Y509_9EURO        Unreviewed;       542 AA.
AC   A0A2B7Y509;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=Peptidase M20 dimerisation domain-containing protein {ECO:0000259|Pfam:PF07687};
GN   ORFNames=AJ80_05306 {ECO:0000313|EMBL:PGH16091.1};
OS   Polytolypa hystricis UAMH7299.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Polytolypa.
OX   NCBI_TaxID=1447883 {ECO:0000313|EMBL:PGH16091.1, ECO:0000313|Proteomes:UP000224634};
RN   [1] {ECO:0000313|EMBL:PGH16091.1, ECO:0000313|Proteomes:UP000224634}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH7299 {ECO:0000313|EMBL:PGH16091.1,
RC   ECO:0000313|Proteomes:UP000224634};
RA   Munoz J.F., Mcewen J.G., Clay O.K., Cuomo C.A.;
RT   "Comparative genomics in systemic dimorphic fungi from Ajellomycetaceae.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the peptidase M20A family.
CC       {ECO:0000256|ARBA:ARBA00006247}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PGH16091.1}.
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DR   EMBL; PDNA01000076; PGH16091.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2B7Y509; -.
DR   STRING; 1447883.A0A2B7Y509; -.
DR   OrthoDB; 177966at2759; -.
DR   Proteomes; UP000224634; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   CDD; cd05676; M20_dipept_like_CNDP; 1.
DR   Gene3D; 3.30.70.360; -; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR002933; Peptidase_M20.
DR   InterPro; IPR011650; Peptidase_M20_dimer.
DR   PANTHER; PTHR43270; BETA-ALA-HIS DIPEPTIDASE; 1.
DR   PANTHER; PTHR43270:SF4; CARNOSINE DIPEPTIDASE 2, ISOFORM A; 1.
DR   Pfam; PF07687; M20_dimer; 1.
DR   Pfam; PF01546; Peptidase_M20; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000224634};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT   DOMAIN          276..431
FT                   /note="Peptidase M20 dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF07687"
SQ   SEQUENCE   542 AA;  59868 MW;  35C62007A1D73557 CRC64;
     MLPASAAATR LASFVIRAGQ SIRQPIFPSI LSSYPAFKLR PSPPVLWPSQ ILHRRTFYGH
     IQDVEMAPQL EPFFKEVDNL SDAFINRLRE AVAIPSISAQ DECRPEVVRM GNWLASELKA
     LGAHVELRPL GKEPGKEHLD LPPVVLARYG NDANKRTILV YGHYDVQPAL KEDGWATEPF
     DLTVDEKGRM FGRGSTDDKG PVLGWLNVIE AHKKAGVEFP VNLLCCFEGM EEYGSQGLEE
     LVKDESKKFF KDTDAVCISD NYWLGTEKPC LTYGLRGCNY YSLTVSGPGQ DLHSGVFGGT
     AHEPMTDLVH LLSKLVDAKG NILIPGIKDL VAPLTEEEKS LYNTISYTMD NLHESLGSET
     SIFSSKEETL MARWRYPSLS IHGVEGAYSA PGAKTVIPAK VIGKFSIRTV PNMESEDVNK
     LVFDYVNAES AKLNSKNTVD ISLQHDGKWW VASPNHWNFK AASKAVEQVF GVVPDMTREG
     GSIPITLTFE EATGKNVLLL PMGSSTDAAH SINEKLDKRN YIEGTKLLGA YLHYVAKEPV
     AE
//