ID   A0A2B7YLY8_9EURO        Unreviewed;       459 AA.
AC   A0A2B7YLY8;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PGH21637.1};
GN   ORFNames=AJ80_03070 {ECO:0000313|EMBL:PGH21637.1};
OS   Polytolypa hystricis UAMH7299.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Polytolypa.
OX   NCBI_TaxID=1447883 {ECO:0000313|EMBL:PGH21637.1, ECO:0000313|Proteomes:UP000224634};
RN   [1] {ECO:0000313|EMBL:PGH21637.1, ECO:0000313|Proteomes:UP000224634}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH7299 {ECO:0000313|EMBL:PGH21637.1,
RC   ECO:0000313|Proteomes:UP000224634};
RA   Munoz J.F., Mcewen J.G., Clay O.K., Cuomo C.A.;
RT   "Comparative genomics in systemic dimorphic fungi from Ajellomycetaceae.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 30 family.
CC       {ECO:0000256|ARBA:ARBA00005382}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PGH21637.1}.
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DR   EMBL; PDNA01000032; PGH21637.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2B7YLY8; -.
DR   STRING; 1447883.A0A2B7YLY8; -.
DR   OrthoDB; 1844890at2759; -.
DR   Proteomes; UP000224634; Unassembled WGS sequence.
DR   GO; GO:0004348; F:glucosylceramidase activity; IEA:InterPro.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR033452; GH30_C.
DR   InterPro; IPR049161; GH59_cat.
DR   InterPro; IPR001139; Glyco_hydro_30.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR11069; GLUCOSYLCERAMIDASE; 1.
DR   PANTHER; PTHR11069:SF23; LYSOSOMAL ACID GLUCOSYLCERAMIDASE; 1.
DR   Pfam; PF17189; Glyco_hydro_30C; 1.
DR   Pfam; PF02057; Glyco_hydro_59; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000224634};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..459
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012021728"
FT   DOMAIN          57..332
FT                   /note="Glycosyl hydrolase family 59 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF02057"
FT   DOMAIN          368..453
FT                   /note="Glycosyl hydrolase family 30 beta sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF17189"
SQ   SEQUENCE   459 AA;  49257 MW;  63C467759211C3AE CRC64;
     MRTLSTAVAI AAHVGMALSQ AQITVNTGST LQEIDGFGVS QAFTRAAEFE GMNPEPRRKG
     LDYLFSTTTG AGLTIIRNRI GSKGQGDSIL PVSPGSPNAT PNYVWDGSDS SQVWFSKEAM
     AYGVNQIYGN AWSAPGFMKT NNNEANGGYL CGVSGRSCGS GDWRRAYAHL LTQYVKFYAQ
     EGVNVTHLGF LNEPDFVATY SSMQSDGNQA ASFIPILHQT LAENDLSHVQ ITCCDAMGWS
     SQGTMTGQLV QQGMEQYLGV ITSHMYTGDP NSPMNTKLKT WQTEACDLQS SWCTTWYSNG
     GLCEGMTWAN KLHTGIVNAN LSGYLYWEGV EVNQFQAASY LVASDGTNVI PSGRLWAFAQ
     WSRFVRPGAR RVSHSGSVNN VGIGAFKNTD GTVAVVFTNN GSNQNVRVNF NGFTPSTAIA
     YVTDNNRAVA ETAVTLSGGS VTLDVPGRAV LTLKLSASE
//