ID   A0A2B7YQZ5_9EURO        Unreviewed;       870 AA.
AC   A0A2B7YQZ5;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=XPG-I domain-containing protein {ECO:0000259|SMART:SM00484};
GN   ORFNames=AJ80_02560 {ECO:0000313|EMBL:PGH23308.1};
OS   Polytolypa hystricis UAMH7299.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Polytolypa.
OX   NCBI_TaxID=1447883 {ECO:0000313|EMBL:PGH23308.1, ECO:0000313|Proteomes:UP000224634};
RN   [1] {ECO:0000313|EMBL:PGH23308.1, ECO:0000313|Proteomes:UP000224634}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH7299 {ECO:0000313|EMBL:PGH23308.1,
RC   ECO:0000313|Proteomes:UP000224634};
RA   Munoz J.F., Mcewen J.G., Clay O.K., Cuomo C.A.;
RT   "Comparative genomics in systemic dimorphic fungi from Ajellomycetaceae.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PGH23308.1}.
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DR   EMBL; PDNA01000025; PGH23308.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2B7YQZ5; -.
DR   STRING; 1447883.A0A2B7YQZ5; -.
DR   OrthoDB; 1779469at2759; -.
DR   Proteomes; UP000224634; Unassembled WGS sequence.
DR   GO; GO:0008821; F:crossover junction DNA endonuclease activity; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProt.
DR   CDD; cd09906; H3TH_YEN1; 1.
DR   CDD; cd09870; PIN_YEN1; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 2.
DR   InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR   InterPro; IPR041177; GEN1_C.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR006086; XPG-I_dom.
DR   InterPro; IPR006084; XPG/Rad2.
DR   InterPro; IPR037316; Yen1_H3TH.
DR   PANTHER; PTHR11081:SF71; ENDONUCLEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G13260)-RELATED; 1.
DR   PANTHER; PTHR11081; FLAP ENDONUCLEASE FAMILY MEMBER; 1.
DR   Pfam; PF18380; GEN1_C; 1.
DR   Pfam; PF00867; XPG_I; 1.
DR   PRINTS; PR00853; XPGRADSUPER.
DR   SMART; SM00484; XPGI; 1.
DR   SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000224634}.
FT   DOMAIN          140..213
FT                   /note="XPG-I"
FT                   /evidence="ECO:0000259|SMART:SM00484"
FT   REGION          409..453
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          483..580
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          648..806
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          821..850
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        422..439
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        532..580
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        660..678
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        691..746
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        750..789
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        824..850
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   870 AA;  96152 MW;  A1CC23E1E6AB4647 CRC64;
     MNGYPWVSCV HQDVLLKLEC PELCCSVTYL NYVYRLIKAL GPGERISLAK LAVDHLKRTA
     RPIRIAIDIS IWLFQVQASR GGHNPELRTL LYRLIRLVAL PIRPVFVYDG PQRPTEKRGK
     RIGGTSGPAA VIQLSKRLVE LFQFQHHTAP GEAEAECARM QMIGVVDAVI SNDVDAIMFG
     SKTTILNFSK ESSRSGAATH GDVYRTETSE CGNANVKIDR GGMILFALLS GGDYFQAGVS
     NCGQVLATEI AMAGFGADFL QGLQGNDLGD WRSRLQKELH DNEEKHFKRR HKAVNIPDTF
     PDRKILSNYT DPIVSPTPEL LEVGQKLEDD GHINLLGLRD FVKNEFGWKP AKFIRAFSQA
     LISHRLRLGL PPSENDVAMR FCGQRTHFDT DELLELRLEF VPADVVGPDF MSEPTSSPLD
     PLENDNDDEE PEDAEIGDDL AEQSQSAKTP SKTVYDPTKF TRIWLFEAIA QIGMPEAVEK
     WKAAQQAKAS PRKASAASKP SKARSRRTGP KVVDPNMTPG ALHRYFPVGK SSVGKSTVNR
     TQKDIISSQG SQSAASSFPY SVPDKTSYGP TNSGDTQYDD EFPTSSFPTF DPGMNGSQAG
     QEEMYFMHDK GRGPSFFSLE SCEEFDFNSA SFTPRAIEPV KVPLNELHIR GIPPDSPCPT
     LREDTRREDT RRSARLKPVD STEPANSPRE TRRQTKPTST QSTESSPTKK NQRQGSPKKS
     AHLELSSKSP ASDPASSASS SMTVLAELLE NKAHIDDANG PLKRIEDSKS DRAPTIQHSA
     RERKPRRQDP TSMPIPSAAL AQPSHTEAAI EAHDGFWTFT SQLDKTEEHP DRPIDKPSRT
     SKKDLKFTKS GKKIVAGRVS ILDMSELPSS
//