ID   A0A2B7ZBY8_9EURO        Unreviewed;       642 AA.
AC   A0A2B7ZBY8;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   RecName: Full=Partial AB-hydrolase lipase domain-containing protein {ECO:0000259|Pfam:PF04083};
GN   ORFNames=GX50_03211 {ECO:0000313|EMBL:PGH33974.1};
OS   Emmonsia crescens.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Emmonsia.
OX   NCBI_TaxID=73230 {ECO:0000313|EMBL:PGH33974.1, ECO:0000313|Proteomes:UP000226031};
RN   [1] {ECO:0000313|EMBL:PGH33974.1, ECO:0000313|Proteomes:UP000226031}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH4076 {ECO:0000313|EMBL:PGH33974.1,
RC   ECO:0000313|Proteomes:UP000226031};
RA   Munoz J.F., Mcewen J.G., Clay O.K., Cuomo C.A.;
RT   "Comparative genomics in systemic dimorphic fungi from Ajellomycetaceae.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PGH33974.1}.
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DR   EMBL; PDND01000050; PGH33974.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2B7ZBY8; -.
DR   STRING; 73230.A0A2B7ZBY8; -.
DR   VEuPathDB; FungiDB:EMCG_03849; -.
DR   OrthoDB; 5471104at2759; -.
DR   Proteomes; UP000226031; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR006693; AB_hydrolase_lipase.
DR   PANTHER; PTHR11005; LYSOSOMAL ACID LIPASE-RELATED; 1.
DR   PANTHER; PTHR11005:SF160; STEROL ESTERASE 1-RELATED; 1.
DR   Pfam; PF04083; Abhydro_lipase; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000226031};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        101..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        445..462
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          209..297
FT                   /note="Partial AB-hydrolase lipase"
FT                   /evidence="ECO:0000259|Pfam:PF04083"
FT   REGION          156..180
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        156..173
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   642 AA;  71160 MW;  B5A589E58344C6D8 CRC64;
     MKTTDINATP VSSAFSGNED TISIAPSAPE PASIGVVDAE KLCAPASPCP SGSSSQKSIS
     ITALPPIDEE NPYPHHTLFP PLPEYKATSV LASIQWRALR VASFCLSLTF LTGIVLAASV
     SSTLIAANGL YIRIRGGDPE KVRPFWQEEC KRREARESAT RAWDDEKRKQ AAKSSALGSE
     VDAEERNVGL AKAAYEPLEG GQDPLVCNIS YYARRVGLDA ETYRVQTEDG AVITLWHLYN
     PKEYAPIPFS DRDCIGPPST LRTPKADPQS RPADGDRKYP ILMLPGLFQS AGAFCTNDDD
     SLAFFLAKSG YDIWLGSNRY GFHPEHISLS SSDPLFWSWT IKDMATLDLP ALITRVLYET
     NFTKLALIGH SQGTAETFLA LSKHIQPSLG PHISIFCALS PAAYSGPLVN KPYLKFMRLI
     PATCFRLIFG IHAFIPLMLT MHTFLPAPLY ATMGYMVFSY LFKWSDARWD RGLRPRFFQF
     SPIYASAECM RWWLGKGGFA DHGCILSTRE QMARENAEDA RYEAQVVEKK IEAGASGAGL
     PVSTDVDVDL ASAAWYDDRA PPMALWVAGS DQLVDGGRLL RRLKGRREPY VRVVHSKVIE
     EYEHLDVIWA IDSIEKVGME VRRVIWECVQ EDVRGLCRTP EA
//