ID A0A2B7ZCJ4_9EURO Unreviewed; 367 AA.
AC A0A2B7ZCJ4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha {ECO:0000256|ARBA:ARBA00040965};
DE EC=2.5.1.58 {ECO:0000256|ARBA:ARBA00012702};
DE EC=2.5.1.59 {ECO:0000256|ARBA:ARBA00012700};
DE AltName: Full=CAAX farnesyltransferase subunit alpha {ECO:0000256|ARBA:ARBA00043086};
DE AltName: Full=FTase-alpha {ECO:0000256|ARBA:ARBA00042436};
DE AltName: Full=Ras proteins prenyltransferase subunit alpha {ECO:0000256|ARBA:ARBA00041392};
DE AltName: Full=Type I protein geranyl-geranyltransferase subunit alpha {ECO:0000256|ARBA:ARBA00043219};
GN ORFNames=GX50_06680 {ECO:0000313|EMBL:PGH30547.1};
OS Emmonsia crescens.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Emmonsia.
OX NCBI_TaxID=73230 {ECO:0000313|EMBL:PGH30547.1, ECO:0000313|Proteomes:UP000226031};
RN [1] {ECO:0000313|EMBL:PGH30547.1, ECO:0000313|Proteomes:UP000226031}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH4076 {ECO:0000313|EMBL:PGH30547.1,
RC ECO:0000313|Proteomes:UP000226031};
RA Munoz J.F., Mcewen J.G., Clay O.K., Cuomo C.A.;
RT "Comparative genomics in systemic dimorphic fungi from Ajellomycetaceae.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the protein prenyltransferase subunit alpha
CC family. {ECO:0000256|ARBA:ARBA00006734}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PGH30547.1}.
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DR EMBL; PDND01000166; PGH30547.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2B7ZCJ4; -.
DR STRING; 73230.A0A2B7ZCJ4; -.
DR VEuPathDB; FungiDB:EMCG_04382; -.
DR OrthoDB; 20949at2759; -.
DR Proteomes; UP000226031; Unassembled WGS sequence.
DR GO; GO:0008318; F:protein prenyltransferase activity; IEA:InterPro.
DR Gene3D; 1.25.40.120; Protein prenylyltransferase; 1.
DR InterPro; IPR002088; Prenyl_trans_a.
DR PANTHER; PTHR11129; PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT; 1.
DR PANTHER; PTHR11129:SF1; PROTEIN FARNESYLTRANSFERASE_GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNIT ALPHA; 1.
DR Pfam; PF01239; PPTA; 4.
DR SUPFAM; SSF48439; Protein prenylyltransferase; 1.
DR PROSITE; PS51147; PFTA; 5.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Prenyltransferase {ECO:0000256|ARBA:ARBA00022602};
KW Reference proteome {ECO:0000313|Proteomes:UP000226031};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000313|EMBL:PGH30547.1}.
FT COILED 313..343
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 367 AA; 42430 MW; 441B5A8DCBE1F85F CRC64;
MSKYSTPTWT SITPIPLDDG STYYDNDDPE RQRHDVSGNG TYPLATIAYA PAYEEATSYL
RAVMAANEIS ERALELTEDV ILMNPAHYTV WLYRAKILVA LEKDLNKEIE WVNKLALQCL
KNYQIWHHRQ LIMSNSKSFP TLPATEQQFL MQMFALDSKN YHVWTYRHWL VRHFKLWDHP
QELSDVETLI NQDVRNNSAW NHRWMLKFGP RGDVDSGMPL GVDEQRGHKG SLDVVDEELI
DAELEYAKAK ILLAPENRSP WAYARGVLRA AGRPLAELKG FAAKFILEEI EDDGAVVKYQ
VKSSLAVEWL ADVYAEEAEK NDAEEEKERK AEAVKMLTLL KDKYDPIRKN YWDYRIRMLD
GESVAVV
//
