ID A0A2B7ZJ59_9EURO Unreviewed; 1818 AA.
AC A0A2B7ZJ59;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=rRNA biogenesis protein RRP5 {ECO:0000313|EMBL:PGH33213.1};
GN ORFNames=GX50_03974 {ECO:0000313|EMBL:PGH33213.1};
OS Emmonsia crescens.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Emmonsia.
OX NCBI_TaxID=73230 {ECO:0000313|EMBL:PGH33213.1, ECO:0000313|Proteomes:UP000226031};
RN [1] {ECO:0000313|EMBL:PGH33213.1, ECO:0000313|Proteomes:UP000226031}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH4076 {ECO:0000313|EMBL:PGH33213.1,
RC ECO:0000313|Proteomes:UP000226031};
RA Munoz J.F., Mcewen J.G., Clay O.K., Cuomo C.A.;
RT "Comparative genomics in systemic dimorphic fungi from Ajellomycetaceae.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PGH33213.1}.
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DR EMBL; PDND01000069; PGH33213.1; -; Genomic_DNA.
DR STRING; 73230.A0A2B7ZJ59; -.
DR VEuPathDB; FungiDB:EMCG_00743; -.
DR OrthoDB; 167902at2759; -.
DR Proteomes; UP000226031; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR CDD; cd05702; S1_Rrp5_repeat_hs11_sc8; 1.
DR CDD; cd05703; S1_Rrp5_repeat_hs12_sc9; 1.
DR CDD; cd05693; S1_Rrp5_repeat_hs1_sc1; 1.
DR CDD; cd05696; S1_Rrp5_repeat_hs4; 1.
DR CDD; cd05697; S1_Rrp5_repeat_hs5; 1.
DR CDD; cd05698; S1_Rrp5_repeat_hs6_sc5; 1.
DR CDD; cd04461; S1_Rrp5_repeat_hs8_sc7; 1.
DR CDD; cd05706; S1_Rrp5_repeat_sc10; 1.
DR CDD; cd05707; S1_Rrp5_repeat_sc11; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 11.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR045209; Rrp5.
DR InterPro; IPR048058; Rrp5_S1_rpt_hs11_sc8.
DR InterPro; IPR048059; Rrp5_S1_rpt_hs1_sc1.
DR InterPro; IPR003029; S1_domain.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR23270; PROGRAMMED CELL DEATH PROTEIN 11 PRE-RRNA PROCESSING PROTEIN RRP5; 1.
DR PANTHER; PTHR23270:SF10; PROTEIN RRP5 HOMOLOG; 1.
DR Pfam; PF00575; S1; 4.
DR SMART; SM00386; HAT; 6.
DR SMART; SM00316; S1; 12.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 11.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50126; S1; 11.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000226031};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552}.
FT DOMAIN 161..263
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 279..348
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 469..543
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 560..634
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 654..723
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 838..907
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 947..1023
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 1055..1126
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 1142..1211
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 1236..1305
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 1325..1396
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT REGION 1..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1402..1531
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..48
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..96
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1407..1425
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1482..1496
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1818 AA; 199277 MW; B9DF5B6F3771C9B5 CRC64;
MKMGPVKRKG NGPDESGSRQ PQKRVKVTDA AQRKDAKGGK KSKNPAEKST DSSDPPSKAP
AVSVLREEEP AFPRGGANVL TPLEQKQIQI QATRDVLFEQ NGAPGEDDID DEDGTQKKSS
KASGSKAKKG KTKSKKNTTS EEPAKEEVRI EGLNFKRIVI GSKVLGQVSS INAHDIGLSL
PNNLTGYIPL TAVSKTLQQK IEKLLNSNQD ENDGSADDEE EEDLELKSYF KLGQYLRASV
TSTETEVNHG KTKGKKHIEL SVDPREANSG LSKSDLVVNA TVQASVLSVE DHGLVMDLGL
EDGQTKGFMS SKEIPHDLQV SQIKEGSVFL CVVTGHNANG SVVKLSANLP TAGSIKKSHF
LTSAPTINSF LPGTAAEILL TEVTSTGMAG KIMGMLDAVV DLVQSGTTTG KEDITAKYHA
GAKIKARLIC TFPTVEPLKL GFSILDHVVK FTPTVLDLHS NSEDTPAISA IIPEVKIKTV
EPGLGVYVQF NDKHYGFVHV SKLSDSKVDS ISATQGPYKV DSTHEARIVG FSALDNLYLL
SFERKVIDQP FLRLEDVTVG AVVKGKIEKL LIGPDGISGL IVSLADGISG LVPGMHMSDT
KLLHPEKKFR EGAQVSARIL SVNLEKRQLR LTLKKALVNS ESPAWMDYSG ILPGNQSPGT
IISIQSHGAI VQFYGEVRGF LPVSEMSEAY IKDPAQHFSV GQVVNVHVLS VDAELRKLVV
SCKDPASFTE SYKNAFENIH PGDTVSGTVF EKSSEDILLK LQDSGLVARL SAEHVADGQS
SRNGAALARI RVGQKLNELL ILNMQKAHRL IKVTNKPSLK QARQRGELPA KFEDLKEGSK
VTGFVKNIIA DGLFVEFLGG LTGFTPKRLV DDDHVNLPNF GYSLAQPISL TVQSIEDDRQ
RFILTLKEAQ TNTQSASDRV KPANNADQSS INPIDEDIKS LDDLTFGRIT KAKVVSVKET
QINVQLAENI QGRIDVSEVF DSWDAIKDRK QPLRYFKAKQ IIPVRILGIH DARSHKFLPI
SHRSGKYPVF ELSAKPSSLE SKDFDPLSLD KVKIGSSWIG FVNNIGDDCL WINISPNVRG
RLRLTDLSDD LSLVGDMAKN FPVGSALKVH VTGIDADKNR LDLSARHGAS PNKTSISDFS
KGEILLGRVT RVTERQVLVQ LSDIAVGAIN LIDMADDYTK VNPAAFHKNE VLRVCVVDID
VPNKKILLSV RPSRVLSSSL PIQDPEITAI SQLKVNDIVR GFVRRVANNG LFVTLGHNVT
AYVRISDLSD SYLKEWQSEF QVDQLVRGRI ILADAESNKL QMSLKESVLE PNYKTPITIK
DLKRGQIVTG KVRNVEEFGA FIAIDGTANL SGLCHRTEMA ELKVEDARKL FEKGDIVKAK
IVKIDYNKER ISLGLKASYF KDSDNESDGE NSEDENEEDV SESEDDGGMH LELESGDDIS
MGGVDLENAL NGDDSESDAS DEDVKMAGTE DAGVTGGLVT SGFDWAGNTT TGADEGNDSD
SDSDNQAAAK KKKRRKPDIQ VDRTGDLDAN GPQSIADYER LLLGEPDSSL LWLKYMAFQL
ELSEVDKARE IAERALRSIS IGQDTEKFNV WVAMLNLENT FGNDDSLEDV FKRACQYNDP
QEIHERMTSI YIQSGKNDKA DELFQTTLKK KFTQSPNIYL NFATFLFDTL AEPERGRALL
PRAIQSLPAH THVDITSKFG QLEFRSPNGD VERGRTIFEG LLSSFPKRVD LWNVLLDLEI
KNGDVEQVRR LFERVLGLGH GIAADGTKTG PKKLKDKQAK FFFKKWLAFE EKAGDGNEKM
VDEVKARAAE YVKAIQEG
//
