ID   A0A2B7ZKA3_9EURO        Unreviewed;      1243 AA.
AC   A0A2B7ZKA3;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=DNA2/NAM7 helicase-like C-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=GX50_03350 {ECO:0000313|EMBL:PGH33781.1};
OS   Emmonsia crescens.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Emmonsia.
OX   NCBI_TaxID=73230 {ECO:0000313|EMBL:PGH33781.1, ECO:0000313|Proteomes:UP000226031};
RN   [1] {ECO:0000313|EMBL:PGH33781.1, ECO:0000313|Proteomes:UP000226031}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH4076 {ECO:0000313|EMBL:PGH33781.1,
RC   ECO:0000313|Proteomes:UP000226031};
RA   Munoz J.F., Mcewen J.G., Clay O.K., Cuomo C.A.;
RT   "Comparative genomics in systemic dimorphic fungi from Ajellomycetaceae.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PGH33781.1}.
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DR   EMBL; PDND01000054; PGH33781.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2B7ZKA3; -.
DR   VEuPathDB; FungiDB:EMCG_09141; -.
DR   OrthoDB; 2333636at2759; -.
DR   Proteomes; UP000226031; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd18808; SF1_C_Upf1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR045055; DNA2/NAM7-like.
DR   InterPro; IPR041679; DNA2/NAM7-like_C.
DR   InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR047187; SF1_C_Upf1.
DR   PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR   PANTHER; PTHR10887:SF525; HELICASE SENATAXIN-RELATED; 1.
DR   Pfam; PF13086; AAA_11; 1.
DR   Pfam; PF13087; AAA_12; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000226031}.
FT   DOMAIN          554..895
FT                   /note="DNA2/NAM7 helicase helicase"
FT                   /evidence="ECO:0000259|Pfam:PF13086"
FT   DOMAIN          909..1114
FT                   /note="DNA2/NAM7 helicase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13087"
FT   REGION          1..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          641..696
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1195..1243
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        10..39
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        656..678
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1196..1210
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1243 AA;  139415 MW;  5E64B3D1D1399FB2 CRC64;
     MDPGPSTARP TAFAKTTHSD QVHAWNTAPE ASGEKSATNT GLGKMKLALG KLAAIQDEPS
     LDDPFKSIDP VIVTGVNQLG SRPAKPKGED LQKLIPLQER GSHLNKQFMG TQWQMGQFFV
     TYANGDSKAI PLNWNHSAVG ANVRVKVMGG NVARKIRFDL SFTNDPDPTL EHTAYVEFDP
     HSDISSYTCI DRVLRETRPE KGKKQRQAQK DKKESYLVIK FKTTGGTGYG LDYESSEFDD
     ETKTLFSYGR QLAKNFDSDG SLKMVTVRVN ASHSIYENDT QVSKKQEKFN VFQDYFENFF
     KDTSLAYHYY RGKGECRPET IFNSLATRKT IADGCGLTHY PAKVSFASLD EAAIILIYGA
     CLEHQRELEI CHEIGKATHQ VAFVDLLESR VLAIVKLTQS ESEPLRIKEG TLAKIKFRPQ
     NSDRNGSRSC FGLSMANVLN LPYGADCLFI VHRKNLPLVS NFAVEVGSRL QYMPASIISK
     IPSKGVQRQV DSINRLCDLA PGGEHTAKWR QSLLNQHAGK KDDVDPTDCL DLSKELVDAI
     VEGFVNDPRF DWSDEQKACL RACRAFPGGI LLIQGFPGAG KTFTIVALGK LFNLLGIHVI
     YSTPTHYAGD AIAETIDKFD AIAGKKTSVI RIYRPGSEEQ AFKSSGIGNS DRPYNGIDDR
     NVEEPSEDAE KEAPKNTEAD IPGESTSNAD KSGDDFLGRF SEDAELTMFS FVTEFEKYNY
     SKSYCLPEKS LEAAVIRRAY NSSGEKLIGN YPSKDQVHIS KGMATLEDLG GDVGLGREVD
     FFEEVRRYHE LMKEGKLSLW SDEDKRNALF SFTKAAHFVV EEAKMIITTN NNAGSTLISS
     HFGKAAKGII NFRDEDWKET EVNSWIPVCH SQYGEKIQGI VMSGDRKQLK PTVISTRENP
     CFNEFASQME TSFFDRLIHM KHPVYKLTRQ RRFRDTFKEF LNYRVYNDEM RSHPSVNDQT
     VNPVWDRVVR NMLRVDDLDF DSGYFVANIE NAVCEIEEST KSRYNTAHVK FVVNLIMENF
     SAKGYDGKDI TIITYYRAQV RRYLQYLLQL AKSGDFPREF HPYVCTVDSM QGKESKVVIL
     DWVISRADTF GDLGFTMDNN RGNVAQSRMR EVMVNVLPAA VGNGTLSVRL SDRTNSLRDR
     VHPKLPYPCA FMQWARSKTI VVYVQGTYAK HVPNDKDTND NGNWNTGGVP MELLAPENNN
     ASSRATVTEK YDTASADKDA PLSTVDVGNA KNKNMEEDQQ ADH
//