ID   A0A2B7ZMR6_9EURO        Unreviewed;       881 AA.
AC   A0A2B7ZMR6;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=MI domain-containing protein {ECO:0000259|PROSITE:PS51366};
GN   ORFNames=GX50_01866 {ECO:0000313|EMBL:PGH35286.1};
OS   Emmonsia crescens.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Emmonsia.
OX   NCBI_TaxID=73230 {ECO:0000313|EMBL:PGH35286.1, ECO:0000313|Proteomes:UP000226031};
RN   [1] {ECO:0000313|EMBL:PGH35286.1, ECO:0000313|Proteomes:UP000226031}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH4076 {ECO:0000313|EMBL:PGH35286.1,
RC   ECO:0000313|Proteomes:UP000226031};
RA   Munoz J.F., Mcewen J.G., Clay O.K., Cuomo C.A.;
RT   "Comparative genomics in systemic dimorphic fungi from Ajellomycetaceae.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|ARBA:ARBA00004604}.
CC   -!- SIMILARITY: Belongs to the CWC22 family.
CC       {ECO:0000256|ARBA:ARBA00006856}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PGH35286.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; PDND01000024; PGH35286.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2B7ZMR6; -.
DR   STRING; 73230.A0A2B7ZMR6; -.
DR   VEuPathDB; FungiDB:EMCG_03384; -.
DR   OrthoDB; 5491616at2759; -.
DR   Proteomes; UP000226031; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   Gene3D; 1.25.40.180; -; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR   InterPro; IPR003890; MIF4G-like_typ-3.
DR   PANTHER; PTHR18034; CELL CYCLE CONTROL PROTEIN CWF22-RELATED; 1.
DR   PANTHER; PTHR18034:SF4; NUCLEOLAR MIF4G DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF02847; MA3; 1.
DR   Pfam; PF02854; MIF4G; 1.
DR   SMART; SM00544; MA3; 1.
DR   SMART; SM00543; MIF4G; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS51366; MI; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000226031}.
FT   DOMAIN          641..775
FT                   /note="MI"
FT                   /evidence="ECO:0000259|PROSITE:PS51366"
FT   REGION          1..167
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          205..336
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        19..54
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        116..152
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        213..235
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        254..289
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        322..336
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   881 AA;  98513 MW;  B8C9AF75D180E73D CRC64;
     MPRPLYNTTQ LPKQLRDELG LSDPTDARKG DRQRSGRVSR KEQRKAERVN NKRTQLGQRG
     KWPQGGVRDG GGNVRSAPPV IGKANGKSHQ TAKATIVTAP KSISKKRKEM VERPEVASEE
     EEDEGDEGGF SDLLNEDDDE DEDFDDSEEG DGSGNEQSAA RPKISRAVED KLAADDAEIS
     TLEKKLGIKG KKGKLPQSFY DEGLADLLGD LGGGSEDESR KRKREGDEWL QRKRLKAQAA
     ARKANKKVGL DSDNESEEDS EDEGSDESDE GSEDGDNENE FEGFDDEEQG KEDSPPKPKT
     RENPYIAPVA DRDAVQRKYI PPSLRGQSSS EAESLTRLRR QVQGHLNKLS EANLVSILRD
     VEKLYQHYPR NSVTTTLIDL LMGMVYDPSV LQDTFIILHA GFIAAMYKVM GMDFGAEFIE
     RIVKRFDEDY ERKDGGISKE MVNAISLLSH LYNFHVIGCS LVFDYIRLFL KEINEVNTEL
     LLKIIKNSGP QLRQDDPSSL KDIILLIQPA VSQIGEAALS VRTKFMIETM TDLKNNRMKT
     GAAASAVSSE HITRMRKILG SLNSRTLRAS EPIRIGRSDI HNSAKKGKWW LVGASWKDDP
     TNQSAPVVDA KVALPDTLAD DVGGDEVDLA QLARAHRMNT DVRRSIFVAI MSAADCRDAH
     IRLAKLRLKR NQEGEIPRVV LHCAMEEEAH NPYYTLIARK LCGERRMKMA FMFSIWDVFK
     RMGEKGDLDE DLDADVDDDA DNAVTSKAIV NLAKMFGSMV ADGALTLGIL KVLDFAYLQP
     KTQTFVELFL VTVMLQTQQK RLKQLQKNGG DEEDFDEKAL ADVFMRTRET PQIVPRLIYF
     IRKVVAKTDI VASKKEKRIV KWGSKVALDA LKVVSRAVDN S
//