ID A0A2B7ZSW0_9EURO Unreviewed; 328 AA.
AC A0A2B7ZSW0;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=Endo-arabinase {ECO:0008006|Google:ProtNLM};
GN ORFNames=GX50_00656 {ECO:0000313|EMBL:PGH36471.1};
OS Emmonsia crescens.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Emmonsia.
OX NCBI_TaxID=73230 {ECO:0000313|EMBL:PGH36471.1, ECO:0000313|Proteomes:UP000226031};
RN [1] {ECO:0000313|EMBL:PGH36471.1, ECO:0000313|Proteomes:UP000226031}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH4076 {ECO:0000313|EMBL:PGH36471.1,
RC ECO:0000313|Proteomes:UP000226031};
RA Munoz J.F., Mcewen J.G., Clay O.K., Cuomo C.A.;
RT "Comparative genomics in systemic dimorphic fungi from Ajellomycetaceae.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC {ECO:0000256|ARBA:ARBA00009865, ECO:0000256|RuleBase:RU361187}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PGH36471.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; PDND01000007; PGH36471.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2B7ZSW0; -.
DR STRING; 73230.A0A2B7ZSW0; -.
DR VEuPathDB; FungiDB:EMCG_08415; -.
DR OrthoDB; 1435052at2759; -.
DR Proteomes; UP000226031; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd08999; GH43_ABN-like; 1.
DR InterPro; IPR006710; Glyco_hydro_43.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR PANTHER; PTHR42812; BETA-XYLOSIDASE; 1.
DR PANTHER; PTHR42812:SF5; ENDO-ARABINASE; 1.
DR Pfam; PF04616; Glyco_hydro_43; 1.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|RuleBase:RU361187};
KW Hydrolase {ECO:0000256|RuleBase:RU361187};
KW Reference proteome {ECO:0000313|Proteomes:UP000226031};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..328
FT /note="Endo-arabinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012315626"
FT ACT_SITE 45
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT ACT_SITE 231
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT SITE 160
FT /note="Important for catalytic activity, responsible for
FT pKa modulation of the active site Glu and correct
FT orientation of both the proton donor and substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ SEQUENCE 328 AA; 35743 MW; 1C08673DC707202C CRC64;
MRQLLQSFSS LLYLAYFINA VDVSPPQLRF SEPGPHQVIP RDFPDPGFLK VGAEWYAFGT
NAYNKKVQVA KSSDFESWTV LNTDALAGLG PWESPLDHWA PDVITRDDGR LVLYYSGRLK
ESPRYHCVAA AVSEGQDPAG PYHPLEEPFA CHMEKGGSID PAGFLDKDAS RWLVYKVDGN
NIGNGGDCGN SIPPLAPTPI YLQKVAGDAV TRIGDPITIL DRDESDGPLI EAPSLILSSE
GVYFLFYSSH CWTAPEYDVR YATSRSITGP YVKAAEPLIK PGDYGLKAPG GATVANNGER
ILFHANCPAG RCMYAANLEI KGETARIV
//
