ID   A0A2C1K6H6_9BACI        Unreviewed;       581 AA.
AC   A0A2C1K6H6;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN   ORFNames=COD11_06345 {ECO:0000313|EMBL:PGT88155.1};
OS   Bacillus sp. AFS040349.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=2033502 {ECO:0000313|EMBL:PGT88155.1, ECO:0000313|Proteomes:UP000222674};
RN   [1] {ECO:0000313|EMBL:PGT88155.1, ECO:0000313|Proteomes:UP000222674}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AFS040349 {ECO:0000313|EMBL:PGT88155.1,
RC   ECO:0000313|Proteomes:UP000222674};
RG   Agbiome Team Llc;
RA   Bleich R.M., Grubbs K.J., Santa Maria K.C., Allen S.E., Farag S.,
RA   Shank E.A., Bowers A.;
RT   "Large-scale bioinformatics analysis of Bacillus genomes uncovers conserved
RT   roles of natural products in bacterial physiology.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PGT88155.1}.
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DR   EMBL; NUMC01000023; PGT88155.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2C1K6H6; -.
DR   OrthoDB; 38701at2; -.
DR   Proteomes; UP000222674; Unassembled WGS sequence.
DR   CDD; cd00198; vWFA; 1.
DR   Gene3D; 2.60.40.1080; -; 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR10579; CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR; 1.
DR   PANTHER; PTHR10579:SF43; LOW QUALITY PROTEIN: EPITHELIAL CHLORIDE CHANNEL PROTEIN-LIKE ISOFORM X1-RELATED; 1.
DR   Pfam; PF13519; VWA_2; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000222674}.
FT   DOMAIN          74..353
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REGION          543..581
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   581 AA;  64694 MW;  1A7814AF1126688B CRC64;
     MYKYFFAVFM MVLLIVQSIV PFNQASAVDG LSINATVGGQ QTLEIGRDGK VTTTVTFDLL
     PGGTAQANVR KPMDVVIVFD KSGSMSEEVS KGKTKLQLAK EAVQKAVDTF KTNSKNGNDR
     YGIVAFDSDV NSTYTISTLQ SDPNKIIDKI KNAPAEGGTN YTDALKIAEN ILKNSTNRSE
     RDQYIIFMTD GKPTNSSKQV AVNGNYFRLI EHSDYYYYYG YKKYYEKYYD GKFVSIGNNT
     YVISDSKVAI SGTKTMYYDS NGDRNTMAIE HNNNLYYHSH YNQSVPNAIK QHGREQAQSI
     NNNKITLLSI GFGDRDQLDM NYLAELSSMS NGKAERATSD NLVKMFEDIS TNISAEYPSL
     SNGFIRFKLP SGVTVQQTDA VSIVDDSVIM NLKDIKYNPN PPNAGDRSLY YELPVTFTAT
     GDYNFSFDIL YNSGNVTKKG IPFTVKVKER NIPLESISFN PKQKTIYVGE KFKVEDYLSF
     VPFDATNKLI GNVTTDYNVP IIIDRIGHEW YITGKDIGYT DIKAIADENS NISATMRVVV
     KRNTDFSDGG ETGEDDQEGG SDPGDGSENG GGNTYDKENK W
//