ID   A0A2C1Z5I4_9BACI        Unreviewed;       505 AA.
AC   A0A2C1Z5I4;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=Thiamine permease {ECO:0000313|EMBL:PGV52754.1};
GN   ORFNames=COD92_08645 {ECO:0000313|EMBL:PGV52754.1};
OS   Bacillus sp. AFS037270.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=2033499 {ECO:0000313|EMBL:PGV52754.1, ECO:0000313|Proteomes:UP000225442};
RN   [1] {ECO:0000313|EMBL:PGV52754.1, ECO:0000313|Proteomes:UP000225442}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AFS037270 {ECO:0000313|EMBL:PGV52754.1,
RC   ECO:0000313|Proteomes:UP000225442};
RG   Agbiome Team Llc;
RA   Bleich R.M., Grubbs K.J., Santa Maria K.C., Allen S.E., Farag S.,
RA   Shank E.A., Bowers A.;
RT   "Large-scale bioinformatics analysis of Bacillus genomes uncovers conserved
RT   roles of natural products in bacterial physiology.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC       {ECO:0000256|ARBA:ARBA00008974}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PGV52754.1}.
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DR   EMBL; NUNF01000016; PGV52754.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2C1Z5I4; -.
DR   Proteomes; UP000225442; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR   InterPro; IPR012681; NCS1.
DR   InterPro; IPR001248; Pur-cyt_permease.
DR   InterPro; IPR045225; Uracil/uridine/allantoin_perm.
DR   NCBIfam; TIGR00800; ncs1; 1.
DR   PANTHER; PTHR30618; NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER; 1.
DR   PANTHER; PTHR30618:SF0; PURINE-URACIL PERMEASE NCS1; 1.
DR   Pfam; PF02133; Transp_cyt_pur; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        64..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        93..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        126..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        172..189
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        201..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        240..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        286..310
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        330..348
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        369..389
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        395..416
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        436..457
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        463..482
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   505 AA;  55752 MW;  0BCB65316A676FC1 CRC64;
     MAVIRLPCLG NRVRYSFSIL KILLINTKLS MGGSSMSQET EKGISLTGKD IMPSTSSERT
     MSAVAYFILW VGIAVQLVTP ITAAQLYPAL SPAQIIIACI LGNLIVAVLL TLLGDIGVRY
     GIPYAVYIRA CFGYLGTHIP ALIRAIPAIF WFGFQTWMGA YALNTIMEML TGYSNLTLLI
     IIFGAVQIIN TAMGMEAITK FEWLASPSIL IIGIILQVYI MKENHITFGE IFSKGGEGGI
     SLGYGVVVMM GTYITMALNA PDFTRFLKTK FESSETNWWK INKGSFWAHI FGLIGSMLLF
     TIIGLTSGVA TGTWNPIDAM VQTMGQDNPL LLIVCLAFVI LAQWSTNISA NLLPPGYIIV
     NLFPRKISFA KGAIIAGVIG LLIQPWNYAD YVPQILLAIT ATLAPIVGIM FTDYYLLRKR
     QLNISELYKV NGQYKYWNNV NPAAIISYIP AGLSVFLLPD YGFFSALLIS GILYYSLMKY
     WICKIYDQPE ITNSTVIVQE VNHKL
//