ID A0A2C5VZ34_9PEZI Unreviewed; 1000 AA.
AC A0A2C5VZ34;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Cyclic nucleotide-gated olfactory channel {ECO:0000313|EMBL:PHH49119.1};
GN Name=CNGA2 {ECO:0000313|EMBL:PHH49119.1};
GN ORFNames=CFIMG_006469RA {ECO:0000313|EMBL:PHH49119.1};
OS Ceratocystis fimbriata CBS 114723.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Microascales; Ceratocystidaceae; Ceratocystis.
OX NCBI_TaxID=1035309 {ECO:0000313|EMBL:PHH49119.1, ECO:0000313|Proteomes:UP000222788};
RN [1] {ECO:0000313|EMBL:PHH49119.1, ECO:0000313|Proteomes:UP000222788}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 114723 {ECO:0000313|EMBL:PHH49119.1,
RC ECO:0000313|Proteomes:UP000222788};
RX PubMed=23931120; DOI=10.1016/j.funbio.2013.06.004;
RA Simpson M.C., Wilken P.M., Coetzee M.P., Wingfield M.J., Wingfield B.D.;
RT "Analysis of microsatellite markers in the genome of the plant pathogen
RT Ceratocystis fimbriata.";
RL Fungal Biol. 117:545-555(2013).
RN [2] {ECO:0000313|EMBL:PHH49119.1, ECO:0000313|Proteomes:UP000222788}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 114723 {ECO:0000313|EMBL:PHH49119.1,
RC ECO:0000313|Proteomes:UP000222788};
RX PubMed=24563841; DOI=10.5598/imafungus.2013.04.02.14;
RA Wilken P.M., Steenkamp E.T., Wingfield M.J., de Beer Z.W., Wingfield B.D.;
RT "IMA Genome-F 1: Ceratocystis fimbriata: Draft nuclear genome sequence for
RT the plant pathogen, Ceratocystis fimbriata.";
RL IMA Fungus 4:357-358(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHH49119.1}.
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DR EMBL; APWK03000267; PHH49119.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2C5VZ34; -.
DR STRING; 1035309.A0A2C5VZ34; -.
DR OrthoDB; 1330350at2759; -.
DR Proteomes; UP000222788; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR CDD; cd00038; CAP_ED; 2.
DR Gene3D; 2.60.120.10; Jelly Rolls; 2.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR006553; Leu-rich_rpt_Cys-con_subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45638; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR PANTHER; PTHR45638:SF11; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF16643; cNMPbd_u2; 1.
DR Pfam; PF00646; F-box; 1.
DR Pfam; PF13516; LRR_6; 2.
DR SMART; SM00100; cNMP; 2.
DR SMART; SM00367; LRR_CC; 7.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 2.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS00888; CNMP_BINDING_1; 1.
DR PROSITE; PS00889; CNMP_BINDING_2; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 2.
DR PROSITE; PS50181; FBOX; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Reference proteome {ECO:0000313|Proteomes:UP000222788};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 69..186
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 260..407
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 554..609
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT REGION 194..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 455..557
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 706..742
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 537..552
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 716..742
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1000 AA; 110188 MW; 6D699B2E0E538BFC CRC64;
MRRSRTSQSS AFRALASLNN GTSQDPAALI RSFNVETNPT RPVYPSPLTA STIQDMPLDL
LDRVRSFPLF NSAPEEFLVA VGQHLKPQIH TPSDHIIREG DEAKAMYWIV RGVVAVTSRD
GEAVYAELKP GSFFGEISII MNIPRTATIV ARTKCLLLSL KKEDFQVELP KFPEMEKLIR
DEAQERLTIL KKKRQDRLLT QHQTRHSQSG ALSRDAQQTS PPNPKKRKSP SPSLVEGPSV
GSALGSAQVN IRTTLKELPL FSTLPADVLH FLGLSAQPKT YPPFTDIVLQ GTPGNEIYFI
VRGEAEVIHD TWAADTSPNA RNEVDTNNST AQGLQSAPYI AMAQRPRLRQ GQYFGEVASL
GLAHKRTATV KAITTVECLM IPGPALEELW RNSPPDIREQ VEETAKERFN NSSDGDVVMT
EVAAVDTGSA KCSLGHREKC NQSVTDQFAS FMFSGSAKPM TQTPDEKSRP TPDPDPFLSV
DMENLRNRRK GSIAPPTPPA DSSSPALSHV KPVHPLSMDP MSITAPPVAP LHSPPPDRDE
APAKRARIQP LRRESAKQPV PDPVLEMVFV TLDISELMRL RRVCAHWKRI LTTSPKVCLR
VDLSLFNRVI TDQLIKDVLA PFIGQRPEYI DISNCFHMTD DGFNSLWKSC GQNVKCWKMR
SVWDVSANQI LEMSEHSKMM EEIDWSNCRK IGDNLLARVT GWVVPEIPPG PPGPLQRSAT
TGSKGKMSPQ KQRQAPQQPV QRAATMSIPG TVVGCPKLKK LNLSYCKHIT DRSMAHLALH
ASSRLESLTL TRCTTISDAG FHSWASFRFT NLTHLCLADC TYLSDNAIAA LVNAAKNLTH
LDLSFCCALS DTSTEVVALG LPRLKELRLA FCGSAVSDGS LGCVALHLNE LEGISVRGCV
RVTGGGVESL LEGCSKLKWL DVSQCRNLEP WVRSGAISRY GHDERGGNGI PEGQEIITPP
PVPEPSGPRL FVNRSRALAP RRRDREKVKF ILQKGGFGLR
//
