ID A0A2C5WUS6_9PEZI Unreviewed; 4918 AA.
AC A0A2C5WUS6;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Hydroxamate-type ferrichrome siderophore peptide synthetase {ECO:0000313|EMBL:PHH49945.1};
GN Name=sib1 {ECO:0000313|EMBL:PHH49945.1};
GN ORFNames=CFIMG_006224RAa {ECO:0000313|EMBL:PHH49945.1};
OS Ceratocystis fimbriata CBS 114723.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Microascales; Ceratocystidaceae; Ceratocystis.
OX NCBI_TaxID=1035309 {ECO:0000313|EMBL:PHH49945.1, ECO:0000313|Proteomes:UP000222788};
RN [1] {ECO:0000313|EMBL:PHH49945.1, ECO:0000313|Proteomes:UP000222788}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 114723 {ECO:0000313|EMBL:PHH49945.1,
RC ECO:0000313|Proteomes:UP000222788};
RX PubMed=23931120; DOI=10.1016/j.funbio.2013.06.004;
RA Simpson M.C., Wilken P.M., Coetzee M.P., Wingfield M.J., Wingfield B.D.;
RT "Analysis of microsatellite markers in the genome of the plant pathogen
RT Ceratocystis fimbriata.";
RL Fungal Biol. 117:545-555(2013).
RN [2] {ECO:0000313|EMBL:PHH49945.1, ECO:0000313|Proteomes:UP000222788}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 114723 {ECO:0000313|EMBL:PHH49945.1,
RC ECO:0000313|Proteomes:UP000222788};
RX PubMed=24563841; DOI=10.5598/imafungus.2013.04.02.14;
RA Wilken P.M., Steenkamp E.T., Wingfield M.J., de Beer Z.W., Wingfield B.D.;
RT "IMA Genome-F 1: Ceratocystis fimbriata: Draft nuclear genome sequence for
RT the plant pathogen, Ceratocystis fimbriata.";
RL IMA Fungus 4:357-358(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHH49945.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; APWK03000160; PHH49945.1; -; Genomic_DNA.
DR STRING; 1035309.A0A2C5WUS6; -.
DR OrthoDB; 1778695at2759; -.
DR Proteomes; UP000222788; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR CDD; cd05918; A_NRPS_SidN3_like; 1.
DR Gene3D; 3.30.300.30; -; 3.
DR Gene3D; 1.10.1200.10; ACP-like; 5.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 6.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 3.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 6.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527:SF2; FERRICROCIN SYNTHETASE (NONRIBOSOMAL PEPTIDE SIDEROPHORE SYNTHASE ) (EUROFUNG); 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 3.
DR Pfam; PF00668; Condensation; 5.
DR Pfam; PF00550; PP-binding; 6.
DR SMART; SM00823; PKS_PP; 5.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 3.
DR SUPFAM; SSF47336; ACP-like; 6.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 11.
DR PROSITE; PS00455; AMP_BINDING; 2.
DR PROSITE; PS50075; CARRIER; 6.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 3.
PE 4: Predicted;
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000222788}.
FT DOMAIN 552..625
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1612..1689
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2173..2246
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 3264..3339
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 3813..3890
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 4373..4446
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 2255..2274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4918 AA; 536095 MW; 2064EAA6E35B30B1 CRC64;
MAASNQQPTR VSGPDLLHEL VLEGYSDAEF DTRKVAIEAL LKDSTIDSVS YAELDSLSSL
LGDEISQHLS LCQDTLGNRQ PVVPILLPQC LELYIAQLAV LRAGAAFCPL NMDTPPDRLN
FILNDVDARL VLVAPDAAGS FARTSKVSCL AVQLGEMRAR ATDIHSGGNS PRATTGVGPG
AANVHTDSLS YVMYTSGSTG VPKGVGVSHR AATQSLLAHN RHIPSFSRFL QFAAPTFDVS
VFEIFFPLFR RATLVSAYRP AMLDDLPGII RKLRVDACEL TPSVAGSLLV KREHAPELKL
LLTIGEMLTE RVISEFGGSE ARESILWAMY GPTEAAIHCT LAPALPANAS PSSIGFPLDP
VSCFVVSEDG PFQVLEVGDV GELAIGGYQL ADGYINRPEQ TAAAFIDTPF GLLYRSGDRA
LMRPDGTFEC LGRISEGQVK LRGQRMELGE VEHAALRFPG CHGAVAAVIS QVLVLFCAVE
QTLDGQDTGN LAPVSIQIAA ECRRWLPTYM LPGEIVTMAS FPRLASGKVD RKTLKGEYAS
RMAEESATGE DKDLDEFQKR ILEQIEELVG ASVSPEMALA SAGIDSLVAL RLAARLRQDG
INIHALEILR AKRILDIAHL AASSARQDTV VGVNTNVDLA YESISDVLVP REDVEAVISC
APIQNAMLAE TAKDSKAYCN QISLAFDFGV TLNQIQSSFK ELVSLNPMLR SSFVELPNGH
FAQLILKKEA QRDVIRVFDG KSGGPAANIS IGLTQPLVIS LSQLSPESAP AAILHIHHAL
YDGWSLDMLR ADWSDLLRSK SVSPRPPFST VTAFFAQNQL IAKSNCSEFW ASHLNGWEPA
AFPHLSQWAR CDTAKVSNAS HVACLDRLSK SGLIRASRAL RCAPQTFFQT ALIWLLSQMT
ASSSVVIGNV FSGRTIPVPG IESVIGPCLA SLPLRTDLST TSSAAEALRL VHSTERVILD
YLAMPLRDIK KVIRAGPGTP LWNVLFAYQE TLVEAESLVH EIGHVDYSES DILVEIQPAG
DKYFCSITYN EMVLPSSVAE ILTKQLEESV FLLSTGAVNT LDEITLNLGN DLLSIYNPVH
EPLSRIPDVS VAFEQVVAQA PHKDALIFLK APVEAGTPPE IETLSYRDLN NCANQIARLI
QCIFPPTPTG GVVAVIMEKS PLLYKTILGI VKSGHAYLPL LPSTPHARVA TIIEHANVGL
CLVDSGTLET LGHSLNCQVV NLETSNLSSL SRESVWPSLD PNRPAYIIYT SGTTGVPKGV
VATHLNLLGN VDVLSKLYPV SENSRLLQAC SQAFDVSVFE IFWTWICGLP LCTGTKETLF
EDLEGAIREL KVTHLSMTPT VASLVRREAV PEVRFLVTAG EPMTEGVYRE WAVDGSLFQG
YGPSETTNIC TVKQMMPGEY IGHLGFSFTN TSSFVMSPSS LTALPIGSVG ELVFGGDQIT
AGYLNSPELT AAKYQMHPVY GRLYRSGDLG RMLPDGSLMI LGRIDDQLKV RGQRVDVGEI
NGIITNSGLG SASVTILVKD GLLSSFYVSN CGQSLSEKHK SLRKLVFSQL KSSLLSYMIP
SFVIPVGSVP LTPSGKIDRK SLVELFSRLS SEEAALFGTP VSGDGNSFLE AGSWSPHEKA
VSQAIATVLD IDVNTIGLWT PLTSLGLDSF AAIRAAKGLS LLLSCKVPVA SLFRFPTVAQ
LSKQIGPSSH AEPPRAEPTP DSWIDESFVA QTTAKFHDQG LVVEAVLPCL PLQTAMLASA
HEDTYLCRST FALKIPVSEV RALWTKIHSI RGILRTCFMP GPTIEFPFVQ VQLSASCELV
WISESDSIEG CFSRIKHALG SSVGSLRAPI GLGTVCENGQ DILCMLMHHA LYDGIAMDIL
FSEIDALASG TEVPPDADYG AFLRSALTLP TSTMSFWEAH FEGFTPNTFD KRPSVGYKSS
AEDLKSTVMR CNFSTRLSKL ESRAREAGVS LLPVFQAAWA TTIGLSLQMA DVCFGNVFAG
RNADVADFDC LVAPCFNTLP FRVNFDKHSF LQIIQLVKHF QSLNTETVPY TFTALRDIQR
QVVQRAGPGS LFNTLLLLQP PSSTSRDNAV WETLSDDSKM DVPIVCEVQL SSAADSFDVL
LHYDVSFVST PFVEKLIELL ACVLERIATL PFSSIPEFEL LPESLKLIRE HSPTLKDCTR
PPIQSTTDSY EWSHTELAIR AVFAKLSNVA ESKVKPYSTI YQLGLDSINA VQVASALRMQ
GFSVSGVDVL ECLSCASLAE RITITSNLQD QKYDTPASSD AIMTPRSSPE MTPVTGISGS
PPCEEMVFDC TPMQDTMIAE FIKTDGTAYF NHLVLQMDKS ITRHQIKNAL EGLVSAQPML
RAGFVPADLS SLGRATNQML VYPSILVPLQ EGDSHFDLHA WKTSCARSAL NDLSFPAWAV
ALFEDDKGSL ILAFALHHAL YDAASLQMIL TAFSDILRGN YVSASRIDLA VKKLESLHVS
SSVEAEKTWR EIGKAMVVND FPTLTPLSVS SKKSLSLSLS LSPSAAEIKQ SIRDNGISTQ
AYMQATWTRV LGAYLGETNV TFGIVLSGRT DPQLEDAPFP CVTTLPIVLC DSVNNRDLLE
ASSKSAMKMQ RYQYLRLSDI NCWVGRPNSR LFDTILVVQR DDNHADFPWQ ILEDEGTVTY
PVSLEISSNG AEGLLAKLIF WSDVVPSEQA KLMLQQIDAV FSDLIRNPDG SRDELWRDNK
QIVSVLPPAV PLIPTRHSLL HEFVENMARK QPEATALEFI DAIDGDQVAS RSWTYKQLDQ
LGDVVAEMLC SHVQIDDVVA IHFDKCPEAY FAILGILKAG CAFLALDPSA PSARKQFILA
DSKATLVVCA SSGPTLDIDP NALLPLDVNT LMSRPVPERH PTSLARPDTR SYCLYTSGTT
GTPKGCELTH SNAVQGMKAF QHLFEGTVTS SSRCLQFAAF HFDVCVLEQY WTWSVGMPVV
AAPRDLILAD IEHTLATLRI SHVDLTPSLA ALVRPEKVPS LWNGVFITGG EQLRREILDS
WGPLKVIYNA YGPTEATIGV TMRQKVPENG RPANIGQQFP NVGSFVLAPG TDIPVLRGGV
GELCVSGPLV GKGYLGRPDL TEERFPILQT FGERVYRTGD LVRVLCDGSF DFLGRADDQV
KLRGQRLELG EISHAICTKV REIKHAVCLV AKHRVTGKDL LVAFVSEDAK SCATTATASG
QQQPHLIDTP LCNKAKAACK EKLPVYMIPT YILGISFMPL SSNNKAEVKQ LRAMFSELSP
SRLLQISRPP DVGSSARAHG DSLGIACDTE NTIIHALRDF SGLREVDRTS SFFDCGIDSI
SVARFVRLLR KHGLEGVSPA LVLQNPTSAE LAVALKEADS AGSAKIKEAA KRVAACDHLF
RSTAINALKV QSEAIEYVAP CTPLQDGMIS RAMINRDGIY FNPFVFRLRD GLDIQRLKES
WALLVEDNAI LRSAFVPTPA GYVQAALRST DICWKEVSLR HESGLSDLIA SLQSTWIEKN
HPVIRTPVEL TLVSTPAKKM MIVQIFHGVY DGESFGLILS QVASRLHPQR KVDIPNSVPS
FKEVLCYGPL WESQESKEFW ARHLAEWTPS KFSVPYSSSS SHPLPASVKA GIRLDCKPLI
TTQTTPGASW AGIALSLWMF ILSSHLSGNI TTGILAAGRA LELENTDFTI GPLFNTVPFH
LSLNGKETWT DVVLRCQEFL AGLHKVQHTS LRDLQKLFGG GKPLFESLFS YRTEQTQNWS
DLWQEIETPG AGANADYALA FEATKLAGHE MELVLVAKPG ILNEADLQGI LDELAVKVHS
FNAHLPFRVA LPMQSSSTTI SQPPSMSSLP KETLLSPLVK LLIAEFSVFS GIEISEINPS
SSVASLGLDS IDVVRFSSHL RTSANITLAP FNIMKHETVQ AIAEFLSSQS ALVPLEAEYE
AQRGDSKWKA LVQRISSSVN LSGLYDVEAV LPATPLQETM VAKMLQSDYE LYFNHDLREV
AAGVDICKLK SAFETLVRER PILRTCFAPI SDTTIDVSFA QVVRKGPFLV DSLDLGSLDR
LSQVISDART QAAAADSSVT PLFQVRFIAA EQKNFVLLSI AHALYDGWSL GLLHEDLISA
YHGCLTARPS PEPFLKGIFM TESQAASDFW KSYLSAASPT LIAPSRDASA DSSNASQLKL
VSLLSSAEVK SFAKSHSVSV QSLGLAVWSS VLSSLVSSLD VTFGVVLAGR DLPGAQGLMF
PTMNTVAVRA TLHGSMLEFV KYLDSGFGQL RQFQSYPLRK AVFGALKTSK STALFNTLFL
LQKKPSTESS RPSLFLNSAG DAQAEYPISI EMELSDDLVV WHASIDPEFR IDKILSMLDK
TLAVLVSRPN DHIAELSSSI ASGTNWSYIP RQQSIMEEIS DDYESPAEND EWTPAESIIR
DVLAQTSGLP LEDVVKSSTL YKLGLDSIIA IKVSAILKER GLHVTSRQLL TAEDIKSMAM
TSKPLIETSP SAKAPLLNSS SVSRLVWNPD ISSVASQLHI PTSDIAQVLP CLPMQPYMLT
ACHQSNGVVF CPSFTYKLSG VSIIDTPTIE AAWKSTVCSL PILRTVLIPN SSKEIPFMQV
VLTPLSRSLR DTLRVYHLPD AIPKFGKHEP LVRASISVSM DNSLSFILSI HHALYDANSL
PAIIEVFTNN IQDIQSNSTK NHAIVDMAPW EGLLYQPLLS TEKRKNFWTM KLFRGLSPRN
FENIKPVNPE VRTESFRPSL IPDLTAARGV CAREDISIQA FVFAIFAQEI STANGMCDVT
LGIYMGNSGA CPELHKTFPT LSLIPLSVSI AHGDSVVYTA KKIQSELHLL SDPILAQTGL
HEIYNWTGVS VPHFFNFLAP AVEFGDTRDG VMPVHATPLP PSSNAIAVTL SSRDMWQPVK
DAFWPSPLEA SFQHSIDVEA AVEDNKLNIG IFGAEEISRY RNMEEMVDRV RDKINGFR
//
