ID A0A2C5X8H4_9HYPO Unreviewed; 475 AA.
AC A0A2C5X8H4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Xanthine/uracil permease {ECO:0008006|Google:ProtNLM};
GN ORFNames=CDD81_663 {ECO:0000313|EMBL:PHH61229.1};
OS Ophiocordyceps australis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Ophiocordyceps.
OX NCBI_TaxID=1399860 {ECO:0000313|EMBL:PHH61229.1, ECO:0000313|Proteomes:UP000226192};
RN [1] {ECO:0000313|EMBL:PHH61229.1, ECO:0000313|Proteomes:UP000226192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Map64 {ECO:0000313|EMBL:PHH61229.1,
RC ECO:0000313|Proteomes:UP000226192};
RA De Bekker C., Evans H.C., Brachmann A., Hughes D.P.;
RT "Ant-infecting Ophiocordyceps genomes reveal a high diversity of potential
RT behavioral manipulation genes and a possible major role for enterotoxins.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHH61229.1}.
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DR EMBL; NJET01000111; PHH61229.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2C5X8H4; -.
DR STRING; 1399860.A0A2C5X8H4; -.
DR OrthoDB; 35157at2759; -.
DR Proteomes; UP000226192; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337:SF3; PURINE TRANSPORTER; 1.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000226192};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 141..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 475 AA; 50920 MW; C4B5A3D7A8C980B9 CRC64;
MGLNAYFAFQ VVGINGSGKI PYRTALTAVF FEGLIFVVLA LTGMRQWLVR LVPTTIKTAT
GVGIGLFLTE IGLSYSAGIG AITGGGTSTP LALGGCPYEL LDAQTGMCKS GQMTSPKLWL
AVLGGGILSS LLLAFRVKFS LIIGIALVSI ASWPRNTAIT YFPDSHEGNS RFDFFQQIVA
WHPISSNTLN QIDWSLAVGG THFVLALFTF LYVDIIDTTA TLYSMVCFSG ANSRRKDGDF
NRSTLAYCID ALFISVAALL GCSPVTAFIE SGAGIAEGGR TGLTAIVTGL CFIASIFFAP
LFASIPPWAT GCTLILVGCT MIPQIRSINW DYIGDLLPSF IVMALIPLSY SVAYGLVAGI
LVYTLLNSLI GLVIYLSSGR IEPHHYDLKE YWSFRGTGRA PWFVRAYRAR RLRRQQLQLA
QASAPLGTAT AENHDMGRLR SSALTSHADS TAKDDAVIVA IPAPTLGPQP RASDH
//
