ID   A0A2C5XIP7_9HYPO        Unreviewed;       729 AA.
AC   A0A2C5XIP7;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   13-SEP-2023, entry version 15.
DE   RecName: Full=Ketopantoate reductase C-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CDD81_5061 {ECO:0000313|EMBL:PHH64068.1};
OS   Ophiocordyceps australis.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Ophiocordyceps.
OX   NCBI_TaxID=1399860 {ECO:0000313|EMBL:PHH64068.1, ECO:0000313|Proteomes:UP000226192};
RN   [1] {ECO:0000313|EMBL:PHH64068.1, ECO:0000313|Proteomes:UP000226192}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Map64 {ECO:0000313|EMBL:PHH64068.1,
RC   ECO:0000313|Proteomes:UP000226192};
RA   De Bekker C., Evans H.C., Brachmann A., Hughes D.P.;
RT   "Ant-infecting Ophiocordyceps genomes reveal a high diversity of potential
RT   behavioral manipulation genes and a possible major role for enterotoxins.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PHH64068.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; NJET01000037; PHH64068.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2C5XIP7; -.
DR   STRING; 1399860.A0A2C5XIP7; -.
DR   OrthoDB; 2727909at2759; -.
DR   Proteomes; UP000226192; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR013752; KPA_reductase.
DR   InterPro; IPR013332; KPR_N.
DR   PANTHER; PTHR21708; PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE; 1.
DR   PANTHER; PTHR21708:SF25; PROTEIN PAM1-RELATED; 1.
DR   Pfam; PF02558; ApbA; 1.
DR   Pfam; PF08546; ApbA_C; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000226192}.
FT   DOMAIN          10..167
FT                   /note="Ketopantoate reductase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02558"
FT   DOMAIN          200..323
FT                   /note="Ketopantoate reductase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08546"
FT   REGION          325..444
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          495..524
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          557..600
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          627..729
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        333..355
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        405..429
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        586..600
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        682..704
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        715..729
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   729 AA;  79441 MW;  47FB2C0CC7A5C2E4 CRC64;
     MAPMTPRLKI LSVGGNPVSA FLSWRLQATN ACDVTLVWKS GYEHVAQYGI SFKSPIFGNE
     RFKPRHVVRN PEDASSSRDG PFDYVVLCVK ALPDVYDLAS VIDAVVTPQH TCILINTTHT
     LGVEAAIEER FPTNVVLSLV SGAELTQLGQ SEFEHKGSSE IWVGPANRNS NIPQSIQEDM
     AQALAMTLST GQVECKVSPN IRQQQYDRVI GPIAFHPISV LFETPNHAAL LEKIGVKDMI
     SEVIDELLRL AAANGCEFPS GFKQKTIDDM TKPNLPESIM WQDYVARRPM EVETYLGSPI
     KLARDSKVSL PRIETLYAIL HNINTNNRNR PKPGEGLPPP GILAPGSPVV PSPMPRIPSQ
     QSHRPIMSGM PNGIPNGIPN GMPNGNGMPP RQPRPRNSSN FGPPGGMRRP PPMNGPGPNG
     FPRPPPSVNG GSRAPSRRGS MDGNDLEEFS HLVLYDDIPE GHEPVVSGES DLALRERELQ
     LRQRELALRE QEMRLRRGPP PGPMSRRGPH PMRHSHQAFD DDDDDDDLLD PTAITGIPTI
     DPDNFDMMSV TSRKNRKAAP TAAQFRRNPE FDAPAPSRGS RFRPSFGRNR ASQLSQVPSM
     TDNILEDPMM GFTSNRYATV DRGAMGAGSR ANSLTASRLD ELQYGPGPGG MPGMNGALPR
     RASQSPGNPY SPSLRGGGRP SPPNGYGPPM NGRPSPPDGV RQPVPRYPPG HGNSVAPQQV
     EQHVGRGQW
//