ID A0A2C5XXH0_9HYPO Unreviewed; 546 AA.
AC A0A2C5XXH0;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=Sulfatase N-terminal domain-containing protein {ECO:0000259|Pfam:PF00884};
GN ORFNames=CDD81_725 {ECO:0000313|EMBL:PHH61157.1};
OS Ophiocordyceps australis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Ophiocordyceps.
OX NCBI_TaxID=1399860 {ECO:0000313|EMBL:PHH61157.1, ECO:0000313|Proteomes:UP000226192};
RN [1] {ECO:0000313|EMBL:PHH61157.1, ECO:0000313|Proteomes:UP000226192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Map64 {ECO:0000313|EMBL:PHH61157.1,
RC ECO:0000313|Proteomes:UP000226192};
RA De Bekker C., Evans H.C., Brachmann A., Hughes D.P.;
RT "Ant-infecting Ophiocordyceps genomes reveal a high diversity of potential
RT behavioral manipulation genes and a possible major role for enterotoxins.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- PTM: The conversion to 3-oxoalanine (also known as C-formylglycine,
CC FGly), of a serine or cysteine residue in prokaryotes and of a cysteine
CC residue in eukaryotes, is critical for catalytic activity.
CC {ECO:0000256|PIRSR:PIRSR000972-50}.
CC -!- SIMILARITY: Belongs to the sulfatase family.
CC {ECO:0000256|ARBA:ARBA00008779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHH61157.1}.
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DR EMBL; NJET01000114; PHH61157.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2C5XXH0; -.
DR STRING; 1399860.A0A2C5XXH0; -.
DR OrthoDB; 1365192at2759; -.
DR Proteomes; UP000226192; Unassembled WGS sequence.
DR GO; GO:0004065; F:arylsulfatase activity; IEA:InterPro.
DR GO; GO:0018958; P:phenol-containing compound metabolic process; IEA:InterPro.
DR CDD; cd16147; G6S; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR012083; Arylsulfatase.
DR InterPro; IPR024607; Sulfatase_CS.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR43108; N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43108:SF8; SD21168P; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR PIRSF; PIRSF000972; Arylsulf_plant; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR PROSITE; PS00523; SULFATASE_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000226192};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..546
FT /note="Sulfatase N-terminal domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013174626"
FT DOMAIN 18..362
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
FT MOD_RES 62
FT /note="3-oxoalanine (Cys)"
FT /evidence="ECO:0000256|PIRSR:PIRSR000972-50"
SQ SEQUENCE 546 AA; 60906 MW; 168EEFD87E196625 CRC64;
MLPLILGLAT LAAAASRPNF IFIMADDQDM HLGSLDYQPA VLKHFRDAGS WFVKHFCTVS
ICCPSRVSLL TGRAAHNTNV TDVELPYGGY HKFVAEGLND KYLPIWLQEA GYATYYTGKL
LNGVSATAPE KPRGWTRSAF LVEPGLYNYF NACMAIDHGP LQLYTGLYST DVIANHTIDF
LHDAMEADKP FFLGVAPTAP HGERVVDKTP IMFEAPVPAQ RHEHLFPDAK VARTPDFNQA
ADGSVSYFAV IPPLTDAQIT YSDTFYQRRL QALQALDELV DSVVTKLYTR PDLASNTYLI
YTSDNGYHIG QHRLPPGKTS NIDSDLNVPF FVRGPGIPSA KIITTPTSHT DIVPSIFKFA
GIPLRDEFDG EPMPWTGEGN RQEHVNVEFW GKRFTEGTVF DMEDDEALRN TYKTLRIVGS
DYDFSYTVWC TNEHELYDIK LDPWQMNNIY TNITATSGFS IPLLITRLDT LLLTLKGCTR
NVCRRPWEAL FPGGGVASLR DAMDPKYDAF FDQGQSRVGF SECLDGYETR AEGALFPVAF
GVNCSV
//
