ID A0A2C5Z0T2_9HYPO Unreviewed; 2685 AA.
AC A0A2C5Z0T2;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=TOG domain-containing protein {ECO:0000259|SMART:SM01349};
GN ORFNames=CDD80_2378 {ECO:0000313|EMBL:PHH75425.1};
OS Ophiocordyceps camponoti-rufipedis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Ophiocordyceps.
OX NCBI_TaxID=2004952 {ECO:0000313|EMBL:PHH75425.1, ECO:0000313|Proteomes:UP000226431};
RN [1] {ECO:0000313|EMBL:PHH75425.1, ECO:0000313|Proteomes:UP000226431}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Map16 {ECO:0000313|EMBL:PHH75425.1,
RC ECO:0000313|Proteomes:UP000226431};
RA De Bekker C., Evans H.C., Brachmann A., Hughes D.P.;
RT "Ant-infecting Ophiocordyceps genomes reveal a high diversity of potential
RT behavioral manipulation genes and a possible major role for enterotoxins.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GCN1 family.
CC {ECO:0000256|ARBA:ARBA00007366}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHH75425.1}.
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DR EMBL; NJES01000217; PHH75425.1; -; Genomic_DNA.
DR STRING; 2004952.A0A2C5Z0T2; -.
DR OrthoDB; 6844at2759; -.
DR Proteomes; UP000226431; Unassembled WGS sequence.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 6.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR022716; Gcn1_N.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR034085; TOG.
DR PANTHER; PTHR23346:SF7; EIF-2-ALPHA KINASE ACTIVATOR GCN1; 1.
DR PANTHER; PTHR23346; TRANSLATIONAL ACTIVATOR GCN1-RELATED; 1.
DR Pfam; PF21040; CEP104-like_TOG; 1.
DR Pfam; PF12074; Gcn1_N; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR SMART; SM01349; TOG; 1.
DR SUPFAM; SSF48371; ARM repeat; 3.
DR PROSITE; PS50077; HEAT_REPEAT; 3.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000226431};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1354..1589
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REPEAT 1531..1569
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 1649..1687
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 1993..2030
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REGION 845..864
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2645..2685
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2685 AA; 291510 MW; E8DB8425592EA4AD CRC64;
MPKAVISFNA NLYAMEKALA SSSTATRSAQ LRELEELVAI KTIDQELLGL YLELLFGTHA
LYHDRQSRKT VQRCLATAID AGATTETLLV LARTIYEECA KPGIAASSAF VLLEWCSVFM
QHLAASSRWP SLSNLILLAN AEALEKCLQP NSRNGLVRSA VSISRRGFRK LFAPSESRSN
NLQMAVSALT AKGNQPMAKN APLLGVIAGV CARQSALVPL FEAHKPQYRE FYIREIVNSR
APLPEHLTSG LSDFFAHFIT LDELEKDVIP AIEKGLLRAP EVILGGVLKS LATSLPAAMD
LSATLSGKLL KPLLAAVKSS NPSIVKGVTR AYRPIAKHCS NLRAMDSLMV EIANPLASGK
LASPEQRVLH AKMLEATPLS EQGTRSATST LIAVASKEGN EAALAAEATA LSRCMVTLLK
SEKGVGKPVI DSLSKCLDDK KASSRRLWML RVGDVLRSLV DFEPRLGLTV FVDAVIPKLI
RNFEEVVSNA AAAAQSGILV GAFILVALTP ALQRQFPGSA ATTALTKAAV LTQAMSLVTK
QAVLLNARIY HKIGSAEELM WLSRALASIL PKIDGSTDKE VTLAWSDAMT YLIAAKTVPS
DVQQEAITSL STLYNQKPTA VFRIIVDGLW SSFAGGAAKQ GENKWAPSNL INVLKAVCPD
SNDLAKRETQ IDGKILESQA CALPVLARHE LIPRSSWIDM CLRMSIDPGK LAHDRLDELL
QEVERRTELG SQVCSRASSV FCLFLNANLQ SETIKKAAYN AAAELAFVAP DVVIPRLIKI
VSEDLNVSKI CDFGPVEAAI FRTPEGTCFV DVLSKQKQSK VPNKNDRDYD ILKWEDELRA
QLEQKKGQQR KLTPEETSKV NAQLKKESQI RESVRKAEAR LMRGVGFINS LATGPPTDAT
LWLGTAVTLL LGISDAGAGL IIADEAFAAY IACSKKVTAR LGFMRDYVGV ATLRARGFTE
LEGYGYERLE DLVTRVLYRL HFAGEQRPFD VVSLIYMFPL ILAVLNKGGF GDTDDERDAQ
LVLALEFLSF HTHVCEDEAL PRAELLAALI EAMQNYAQHY KLVKDCFADA CRCAAPNMNH
GEMMVLAKGA IVPQAGVRTT VLQSISAEVD MSDMSYSDEI WLACHDAVAE NHELGKEIWE
ESGFKLDATV PLKMVPYLES RDPQLRGAAA RALASSASSQ KECLGKVIPR LKSMYLELAK
PKLQQLDEFG MPRKMDLSDP WEARQGVATA FKELVSVLDK TQMDDLFDFL IESGPLGDKN
DDVRREMLDA AIRAADVHGR DMIDELMKKF ERILEQPDKG SDAADRVNEA VIIIYGALAQ
HLKAGDSKIP VVIERLLATL STPSETVQYA IAECLPPLVR ACPDKSSKYF ELVTDQLLNS
KKYATQRGAA YGLAGLVLGR GVSTLRDYRI MSMLKSAMEN KKDANQREAA LLGFELLSII
LGRLFEPYVI QVVPLLLSGF GDTNGDVRDA CLAAAKACFG KLSSYGVKKI MPTLLEGLDD
PQWRSKRGAC DLLGAMAYLD PNQLANSLPD IIPPLSGVLN DSHKEVRAAA NRSLKRFGEV
INNPEIKGLV DVLLKALSDP TKYGDEALES LIKVQFIHYL DAPSLALIAR ILQRGLGGRS
STKRKAAQVI GSLAHLTEKK DIVAHLPILV AGLKSAAVDP VPTTRATASR ALGSLVEKLG
EDALPDLIPG LMQTLKSDTG AGDRLGSAQA LSEVLAGLGT GRLEETLPTI LQNVESPTPS
VREGFMSLFI FLPVCFGNSF SNYLGRIVPP ILAGLADEVE SIRETALRAG RLLVKNFAMR
AIDLLLPELE RGLADDSYRI RLSSVELVGD LLFNLTGVKA AAENEDEADE VDDREAGVSL
KEVLGEEKRN KILSALYVCR CDTAGAVRSA AMAVWKVLVP SPRTLKELVP TLTQLLIRRL
GSSNMEHKVI ASNALGELIR KAGDGVLSSL LPTLEQGLQA STDSDAKQGI CLALRELISS
ASPEALEAHE KTLISVVRTA LTDSDEEVRE AAAEAFDSLQ QILGKRAVDQ VLPHLLSLLR
SDKEAENALS ALLTLLTETT RSNMILPNLI PTLISPPISA FNAKALASLS RVAGAAMNRR
LPNIINSLMD NEIKCQEDDL RTELEASFDI VIQSIDEYDG LNTVMNVLLG LLKHDDHKRR
ASTARHLGNF FSETDVDYSR YNQDIIRSLL ISFDDGDQDV VQAAWAALSQ LTKKLKKEEM
ESLVVSTRQA LQRVGVAGAN LRGFELPKGI GAILPIFLQG LMNGTTDQKV QAALGMSDIV
DRASETALKP FVTQMTGPLI RIVSERATDV KAAILLTLNN LLDKMPTALK PFLPQLQRTF
AKSLADPTSE VLRSRAARAL GTLIKYTPRI DPLVGELVTG SKTADVGVKT AMLKALFEVI
SRAGSNMGET SRSAVLSLID MEADERDDKM TVTNAKLLGA LIKNVAEDAA TSLLKNRVLT
THMSNSSAVA LNAVLVESPE TLLQSAMADE LPNLLCLGMA NKSTYIADNF ILATGKVLLS
SAPKSFESTK KVFEALAKVI EPGNPADSRR LALVIVRTLS RTNMEMVRPH VALLAPPIFA
SVRDLAIPVK LAAEAAFVEL FSVADEESRV FDKFMAGAGA DLPANTKRSM GDYFKRVAVR
LGNQARERRE AEGGQGGLGL SNDEQEDEKE IWSVGKLEAS AESFS
//
