ID   A0A2C5Z7T9_9HYPO        Unreviewed;       610 AA.
AC   A0A2C5Z7T9;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Laccase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CDD80_2520 {ECO:0000313|EMBL:PHH75241.1};
OS   Ophiocordyceps camponoti-rufipedis.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Ophiocordyceps.
OX   NCBI_TaxID=2004952 {ECO:0000313|EMBL:PHH75241.1, ECO:0000313|Proteomes:UP000226431};
RN   [1] {ECO:0000313|EMBL:PHH75241.1, ECO:0000313|Proteomes:UP000226431}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Map16 {ECO:0000313|EMBL:PHH75241.1,
RC   ECO:0000313|Proteomes:UP000226431};
RA   De Bekker C., Evans H.C., Brachmann A., Hughes D.P.;
RT   "Ant-infecting Ophiocordyceps genomes reveal a high diversity of potential
RT   behavioral manipulation genes and a possible major role for enterotoxins.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the multicopper oxidase family.
CC       {ECO:0000256|ARBA:ARBA00010609}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PHH75241.1}.
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DR   EMBL; NJES01000227; PHH75241.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2C5Z7T9; -.
DR   STRING; 2004952.A0A2C5Z7T9; -.
DR   OrthoDB; 449862at2759; -.
DR   Proteomes; UP000226431; Unassembled WGS sequence.
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd13854; CuRO_1_MaLCC_like; 1.
DR   CDD; cd13880; CuRO_2_MaLCC_like; 1.
DR   CDD; cd13901; CuRO_3_MaLCC_like; 1.
DR   Gene3D; 2.60.40.420; Cupredoxins - blue copper proteins; 3.
DR   InterPro; IPR011707; Cu-oxidase-like_N.
DR   InterPro; IPR001117; Cu-oxidase_2nd.
DR   InterPro; IPR011706; Cu-oxidase_C.
DR   InterPro; IPR045087; Cu-oxidase_fam.
DR   InterPro; IPR008972; Cupredoxin.
DR   PANTHER; PTHR11709; MULTI-COPPER OXIDASE; 1.
DR   PANTHER; PTHR11709:SF394; PLASTOCYANIN-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00394; Cu-oxidase; 1.
DR   Pfam; PF07731; Cu-oxidase_2; 1.
DR   Pfam; PF07732; Cu-oxidase_3; 1.
DR   SUPFAM; SSF49503; Cupredoxins; 3.
PE   3: Inferred from homology;
KW   Copper {ECO:0000256|ARBA:ARBA00023008};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000226431};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..610
FT                   /note="Laccase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5013038984"
FT   DOMAIN          122..232
FT                   /note="Plastocyanin-like"
FT                   /evidence="ECO:0000259|Pfam:PF07732"
FT   DOMAIN          244..388
FT                   /note="Plastocyanin-like"
FT                   /evidence="ECO:0000259|Pfam:PF00394"
FT   DOMAIN          451..576
FT                   /note="Plastocyanin-like"
FT                   /evidence="ECO:0000259|Pfam:PF07731"
FT   REGION          32..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        33..51
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   610 AA;  67908 MW;  8EA6B09DAD82F86B CRC64;
     MAPFTRAICA LLASLPGGTW KNPFCVPGVE TQPGKLAQTS PPSSVEEPAQ SSPPGTIGRY
     HDEDEDENHL ILPGIVETCA GNTPTTRHKW CKHSIDTDYT RSSPTTGVVR EYWLEATDVI
     LAPDGVSRAL TVINGTVPGP TLYADWGDIV RVHFTNSLHT SHNGSSIHFH GIKQNHTVMS
     DGVPSITECP LAPGKTRTYE WKAEQYGSSW YHSHFELQAW QGIFGGLIIN GPATADYDED
     LGSIFLNDWG HEGPVPMDDK ATIFRGPPIM DSGLINGTNT FGNLGRRYNI AFEAGKSYRL
     RFINAAIDSH FKFMLDNHEM TVIASDFIPL EPYVTKIVDI AIGQRYDVII KANQQQVADN
     FWLRAIPQLP CSLNKNAHNI RAIVHYGKQP SEPTTTGYPF LDKCQDEKEL TPWFARDARE
     PNMTIPIVAS LKIVGDRVKW SVNGTIFTSD WSNPTLLQVI DQVPSFKPST LVVEVPDAEQ
     AFYMVLYNLT PFPHPIHLHG HDFAIISQGP GLLFAEEAIN AFTRTNPPRR DTATLPALGH
     LVLAIRTTNP GAWLMHCHIG WHTSEGFGLQ ILERAKDIPA LLDTERLRRE CQDWKEYQSR
     FSIEQSDSGI
//